結瘤基因 的英文怎麼說

中文拼音 [jiēliújīyīn]
結瘤基因 英文
nodulation gene
  • 結 : 結動詞（長出果實或種子） bear （fruit）; form （seed）
  • 瘤 : 名詞（瘤子） tumour
  • 因 : Ⅰ動詞[書面語] （沿襲） follow; carry on Ⅱ介詞1 [書面語] （憑借; 根據） on the basis of; in accord...
  1. In addition, axud1 has a high homologue with transforming growth facotr beta ( tgf - ) induced apoptosis protein 2 and 12 using blast exploration at genebank database. these suggest that axudl may have a tumor - suppressor function in these organs and may play an important role in tgf - - induced apoptosis

    通過genkbank上blast的搜索結果表明， axud1與tgf -誘導的凋亡蛋白2 、 12 （ taip - 2 、 taip - 12有較高的同源性，提示axud1可能是一個具有腫瘤抑制功能的基因，並可能在tgf -誘導的細胞凋亡中起著重要作用。
  2. Tumor necrosis factor ( tnf ), a cytkine that exerts many pro - atherosclerotic effects in vivo, causes up - regulation of acat - 1 gene expression in human blood monocytes. by luciferase activity assay, tnf - a enhanced acat - 1 p7 promoter activity in thp - 1 monocytic cell line

    細胞因子tnf -即腫瘤壞死因子大量存在於人動脈粥樣硬化斑塊中，本實驗通過熒光素酶活性和rt - pcr測定結果表明， tnf -處理人血單核細胞和單核細胞株thp - 1均增強acat - 1基因p7啟動子活性。
  3. We conclude that the gene we studied is a new loci required for efficient nitrogen fixation and for competitive nodulation of soybeans by bradyrhizobium japonicum strain gx201

    我們認為在突變體菌株gx217中tn5gusa5所插入的開放閱讀框架是一個新的與競爭結瘤有關的基因。
  4. Pp38 was found to have immunosuppressive effect on chicken in vivo and the copy number of 132 - bpr was found to be associated with the attenuation of the virus in vitro, meq was believed to be a potential oncogene, based on its leucine zipper structure and proline - rich domain characteristic of jun / fos family of transcription factors, and may plays an important role in the pathogenicity or oncogenicity of mdv

    其中， meq與132 - bpr兩個基因是mdv - 1所特有，已證實132 - bpr的拷貝數與毒株的體外致弱程度有關， pp38則被證實可抑制機體的免疫應答。 meq基因由於具有與致瘤基因jun fos家族類似的分子結構，因此，我們有理由認為meq基因在mdv致病、致瘤中可能發揮重要的作用。
  5. The env protein deduced from env gene encodes the hydrophilic surface protein ( su ) and the hydrophobic transmembrane domain ( tm ) that determine the specific interaction between virus particles and cell surface receptors during retroviral entry. the su of retroviruses is a highly variable genetic element, containing receptor binding sites and major antigenic determinants. exjsrv - specific dna probes were derived. by using these dna probes in tissue hybridization. we successfully identified jsrv mrna expression and proviruses dna in sheep lung tissues infected with jsrv and control group has no postive signals, validating the use of exogenous virus - specific dna probes in the analysis of oncogenic proviral integration sites and identification of integrated exogenous proviral sequences

    用地高辛隨機引物法標記exjsrv特異的env片段，制備探針，原位雜交檢測spa肺組織中的rna及前病毒dna ，結果表明spa患羊肺組織內有jsrvenv基因mrna的表達，同時也檢測到了前病毒dna ，而相應的陰性對照卻無陽性信號，證實外源性病毒特異的dna探針在致瘤性前病毒的整合位點和整合的外源性前病毒的檢測中具有可信度。
  6. The symbiosis between mesorhizobium huakuii and astragalus sinicus is a chinese - characteristic symbiotic nitrogen fixation system, while molecular genetic study on its early symbiotic interaction is still at primary stage

    本文對新型報告基因?綠色熒光蛋白基因在華癸中生根瘤菌-紫雲英共生固氮體系早期結瘤階段分子遺傳學中的應用進行了探索性研究。
  7. This novel and efficient vaccine, with the non - cellular structure and no exogenous gene modification, is potential to be not toxic to the recipients. together with characters that it is easy to prepare, this non - cellular vaccine is promising in clinic

    的確，由於exosomes具有非細胞結構、未經基因修飾和外源基因導入、對機體潛在危害作用小、制備簡單易行等優點受到大家的重視，成為研究新型腫瘤生物治療制劑和腫瘤疫苗的新方向。
  8. Results : gene therapy for cancers in the whole world is under the stage of r & d recently, but still no drugs come into market. after zealously pursued for several years, gene therapy for cancers has gone into a stable developing stage gradually

    結果：通過專利分析發現世界腫瘤基因治療領域正處研發階段，尚無藥品正式上市，在經過狂熱期后已逐漸進入穩步發展期。
  9. Formation of infection thread and nodules at early symbiotic stage between 2 - 33 and a. sinicus were monitored in situ by using laser confocal scanning microscope ( lcsm ) and fluorescent microscope. an effective vector system and an examination method were established for further molecular genetics study on rhizobium - legume symbiosis

    6 ，以華癸中生根瘤菌jssa16 （ phn109 ）和7653r （ g萬， mut3 ）進行競爭結瘤實驗的結果與預期相符，初步證明了g公助帥mut3雙重報告基因在華癸中生根瘤菌占瘤率研究中的應用潛力。
  10. These genes then were analyzed in 48 additional breast or colorectal tumors, which turned up an additional 365 mutations in 236 of the genes

    然後在另外48例乳腺或結直腸腫瘤中分析這些基因，在236個基因中又出現了365處突變。
  11. In the first large - scale screen of genetic changes in cancer cells, researchers have found that a typical breast or colorectal tumor results from mutations in about 90 genes, with different sets of mutations producing the same type of cancer

    在首次癌細胞遺傳改變的大規模篩選中，研究者發現典型乳腺或者結直腸腫瘤源於約90種基因突變，不同的突變組合產生同種類型的癌癥。
  12. Cea is probably the most extensively characterized human tumor associated antigen. it was discovered in colorectal and pancreatic carcinomas in 1965 and it " s full cdna was cloned in 1987. it is a kind of glycoprotein and it " s molecular weight is 180kd

    癌胚抗原（ carcinoembryonicantigencea ）是一種最常見的腫瘤相關抗原（ taa ） ，也是國際上公認的腫瘤標志物，於1965年首次在人結腸癌和胰腺癌中發現， 1987年克隆出它的全長基因序列。
  13. The comparative analysis of sequences indicated that the sequences of meq in different pathotypes are relatively conserved and the homology of the amino acid sequences is very high. the significant differences include two mutations in both mdv - 1 vaccine strains cvi988 / rispens and 814 strain : the deletion of a proline ( no. l93aa ), and this mutation is just exactly located in a 15 - amino - acid ( eelcaqlcstppppi ) repeat sequence within the c - terminal transactivation domain of meq protein ; and a point mutation with a shift from alanine ( a ) of all virulent strains to serine ( s ) was occurred on the no. 71 aa

    結果發現， mdv不同致病型的meq基因序列相對比較保守，它們相互間核苷酸和氨基酸序列的同源性均很高；但是，與所有七個致瘤性的mdv毒株相比，二個型弱毒疫苗cv1988 rispens株和814株均出現了兩個特徵性的突變：即第194位的p缺失性突變和第71位氨基酸由a變成了s的位點突變；缺失性突變恰恰位於meq基因中轉錄激活域內的一個多脯氨酸的重復序列（ pppp ）之中。
  14. In order to further investigate the role of axudl in human tumor carcinogenesis and the potential association between the axudl gene expression status and the stimulation of transforming growth factor beta in human cancers, the present study was performed in three aspects as follows : ( 1 ) cloning full length enconding region cdna of axudl and construction of eukaryotic vector that expression the fusion protein of axud1 and influenza virus hemagglutin ha epitope tag ; ( 2 ) exploring the time and dose effects of tgf - 1 on the expression - of axudl gene in hepg2 hepatoma cells and spc - a1 lung carcinomas cells, and studying the effects of overexpression of axud1 on the expression of cell cycle and apoptosis related protein in hepg2 hepatoma cells ; ( 3 ) construction and expression of human axudl in e. coli m15. the following main results and conclusions can be obtained from the present study : 1. the full length ecnoding region of human axudl cdna from human peripheral blood lymphocytes was successfully cloned using one step rt - pcr method, and constructed into a eukaryotic expression vector which can be expressed a ha - axud1 fusion protein with axud1 and influenza virus hemagglutin ha epitope tag. the recombinant plasmid was identified by polymerase chain reaction, restriction endonuclease maping and sequencing, this expression vector might be instrumental to further study the function of axud1 protein in tumor cells

    為了進一步研究axud1在人類腫瘤發生中的作用及axud1基因的表達狀況與tgf -介導的信號通路的關系，本實驗研究分為三個部分： （ 1 ） axud1基因cdna全長編碼區的克隆和ha表位標記的axud1基因表達載體的構建； （ 2 ）探討肝癌細胞hepg2和肺腺癌spc - a1細胞中tgf - 1誘導的axud1基因表達的時間、劑量效應以及誘導表達的可能機理，並研究axud1的過表達對細胞周期和細胞凋亡相關蛋白表達的影響； （ 3 ） axud1原核表達載體的構建及其在大腸桿菌中的表達。本實驗的主要結果和結論如下： 1利用一步法rt - pcr成功地從人類外周血淋巴細胞中克隆出axud1基因編碼區cdna ，並將其構建入真核表達載體中，編碼的ha - axud1融合蛋白帶有流感病毒凝血素ha的表位標記肽段。
  15. Then using the technique of patent analysis and the following indicators such as patent numbers of past years, technology life circle, patent technology area, the competitive ability of facilities and so on. we analysed the patents in the area of gene therapy for cancers. swot method is also used to analyse the results from patent analysis, and then the developmental countermeasures are put forward

    方法：通過對國內外生物制藥行業發展現狀的總體分析，及針對國內外腫瘤基因治療領域運用專利歷年數量、技術生命周期、地區分佈情況、專利技術內容、機構競爭力等專利分析指標與方法來進行對比分析，將分析結果結合運用swot分析法，提出相應發展對策。
  16. 8kb cdna with 1362bp orf and codes 454 amino acids with only a sh2 domain. the gene was named as sh2a at chromosome 8p22. we study its structure by blast homologous analysis and its expression by rt - pcr and northern blot

    本文將通過蛋白質分析軟體研究其結構和同源性，利用rt - pcr和northern印跡雜交技術研究該基因的表達情況及該基因與腫瘤的關系。
  17. In summary, we used the cdna microarrays to analyze the differentially expressed genes in the arsenic trioxide induced k562 cells. our results further confirmed in gene expression level that growth arrest and apoptosis could be induced by arsenic trioxide. such induced apoptosis may also involve the functional inhibition of igf

    應用基因晶元技術研究aszo3作用前後k562細胞的基因表達變化，與以往的研究結果相一致，也是通過抑制細胞生長、誘導細胞凋亡而發揮抗腫瘤的作用，在這個過程中， aszo3可能對胰島素樣生長因子有抑制作用。
  18. To gain a molecular understanding of tumor angiogenesis, we compared gene expression patterns of endothelial cells derived from blood vessels of normal and malignant colorectal tissues

    為了能夠在分子水平上了解腫瘤的血管造影照片，我們對比了從正常和惡性結腸癌組織的血管分離到的上皮細胞的基因表達模式。
  19. Sequences flanking tn5 - 1063a can be recovered from the genome of mutant by excision, self - ligation and transfer to e. coli. the total dna of mutant was excised with ecori, which cut the genome frequently but not cut the transposon. after sequencing the self - ligated transpon, dna fragment flanking tn5 was obtained. the result showed 042bm - x1 contains a tn5 insertion in the gene smc00190, which function was unknown and was demonstrated to be related to salt tolerance by this study, and the gene was named as rst - 0x1

    通過ecori酶切突變株基因組，得到完整的tn5 （含有在大腸桿菌中起始復制的oriv ）及其側翼的序列片段，該片段自連后轉化大腸桿菌，以tn5兩端已知的序列設計引物進行測序。 blast的分析測序結果表明， 042bm - x1和042bm - x2中tn5分別定位在苜蓿中華根瘤菌1021染色體上smc02682和smc00419基因內部，本實驗證明它們和042bm耐鹽相關，命名為rst - 0x1和rst - 0x2基因。
  20. And p4. 8 comparison were performed between the 3 t - cell vaccine and plasmid dna vaccine expressing hcv structural gene on therapeutic effects in hcv transplanting tumor murine model. the result showed that the former was obviously superior the latter, which indi

    將3種丁細胞疫苗與表達v結構基因的質粒a疫苗在v移他瘤小鼠捎型內進行治療對比，發現djj者明顯憂於後者，提示， t細胞疫祈在ncv感染的防治研究中可能具有較奸的發展汕景。
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