致弱毒株 的英文怎麼說

中文拼音 [zhìruòdúzhū]
致弱毒株 英文
attenuated strain
  • 致 : Ⅰ動詞1 （給與;向對方表示禮節、情意等） deliver; send; extend 2 （集中於某個方面） devote （one s ...
  • 弱 : Ⅰ形容詞1 （氣力小; 勢力差） weak; feeble 2 （年幼） young 3 （差; 不如） inferior 4 （接在分數或...
  • 毒 : Ⅰ名詞1 （對生物體有害的性質或物質; 毒物） poison; toxin 2 （毒品） drug; narcotics 3 （姓氏） a s...
  • 株 : Ⅰ名詞1. （露在地面上樹木的根和莖） root and stem of a tree above the ground 2. （植株） individual plant; plant Ⅱ量詞（棵）
  1. Pp38 was found to have immunosuppressive effect on chicken in vivo and the copy number of 132 - bpr was found to be associated with the attenuation of the virus in vitro, meq was believed to be a potential oncogene, based on its leucine zipper structure and proline - rich domain characteristic of jun / fos family of transcription factors, and may plays an important role in the pathogenicity or oncogenicity of mdv

    其中， meq與132 - bpr兩個基因是mdv - 1所特有，已證實132 - bpr的拷貝數與毒株的體外致弱程度有關， pp38則被證實可抑制機體的免疫應答。 meq基因由於具有與致瘤基因jun fos家族類似的分子結構，因此，我們有理由認為meq基因在mdv致病、致瘤中可能發揮重要的作用。
  2. The vaccine was developed by passaging eiav strain liaoning ( eiav l ) in donkeys in vivo, obtaining a donkey - adapted virulent equine infectious anemia virus ( eiav da ) and then passaging it in donkey leukocyte cultures for more than 120 times in vitro

    該毒株是將eiavl株（ eiavl ）通過驢體傳代，使其毒力明顯增強，然後在驢白細胞培養物上連續傳代致弱獲得的。
  3. Avian paramyxovirus type 1 ( apmv - 1 ) may cause diseases, named differently in different poultry species, including chicken newcastle disease, goose paramyxovirus disease, pigeon paramyxovirus type 1 disease. the virulence and pathogenicity of apmv - 1 field isolates are different among the poultry species. there is not a technique available for the rapid diagnosis of the disease in all the species and the determination of virulence of the virus at the same time

    禽型副粘病毒（ avianparamyxovirustype1 ， apmv - 1 ）引起的相關疾病主要有雞新城疫、鵝副粘病毒病、鴿型副粘病毒病，但不同禽源的apmv - 1分離株對其它禽類的毒力和致病性都有所差異，雖然apmv - 1在多種禽類廣泛流行，目前仍未有一種既可檢測所有禽源的apmv - 1 ，同時又能鑒別其毒力強弱的快速診斷方法。
  4. The comparative analysis of sequences indicated that the sequences of meq in different pathotypes are relatively conserved and the homology of the amino acid sequences is very high. the significant differences include two mutations in both mdv - 1 vaccine strains cvi988 / rispens and 814 strain : the deletion of a proline ( no. l93aa ), and this mutation is just exactly located in a 15 - amino - acid ( eelcaqlcstppppi ) repeat sequence within the c - terminal transactivation domain of meq protein ; and a point mutation with a shift from alanine ( a ) of all virulent strains to serine ( s ) was occurred on the no. 71 aa

    結果發現， mdv不同致病型的meq基因序列相對比較保守，它們相互間核苷酸和氨基酸序列的同源性均很高；但是，與所有七個致瘤性的mdv毒株相比，二個型弱毒疫苗cv1988 rispens株和814株均出現了兩個特徵性的突變：即第194位的p缺失性突變和第71位氨基酸由a變成了s的位點突變；缺失性突變恰恰位於meq基因中轉錄激活域內的一個多脯氨酸的重復序列（ pppp ）之中。
  5. A few years latter the research showed, vp2 hydrophilic region and antigen variant and virulence of ibdv had very affinity. in order to lucubrate difference of virulence and antigen, and validate correntness of sequencing result, the test adopted sandwich enzyme - liked immunosorbent assay ( elisa ) and antigen caprure - elisa to determine virulence and antigen. and validate correntness of above - mentioned result

    而近幾年的研究表明， vp2高變區與ibdv的抗原變異和毒力強弱有密切的關系，為進一步了解強弱毒株毒力和抗原的差別，並進一步證實測序結果的正確性，本試驗採用雙抗夾心elisa和ac - elisa的方法分別對其毒力和抗原進行了測定，並通過動物試驗證實了，其結果與序列分析結果基本一致。
分享友人
分享到 Line

分享到臉書