陰囊纖維變性 的英文怎麼說
中文拼音 [yīnnángxiānwéibiànxìng]
陰囊纖維變性
英文
fibrosis of scrotum- 陰 : Ⅰ名詞1 （中國古代哲學認為宇宙中通貫物質和人事的兩大對立面之一） （in chinese philosophy medicine ...
- 囊 : 囊名詞1. （口袋） bag; pocket; sack; purse 2. （像口袋的東西） anything shaped like a bag 1. （姓氏） a surname
- 纖 : 纖形容詞（細小） fine; minute
- 維 : Ⅰ動詞1 （連接） tie up; hold together; link 2 （保持; 保全） maintain; safeguard; preserve; keep ...
- 性 : Ⅰ名詞1 （性格） nature; character; disposition 2 （性能; 性質） property; quality 3 （性別） sex ...
- 陰囊 : [解剖學] scrotum; oschea; ocheus; oscheo-; osche-; scrot-; scroti-; scroto-陰囊炎 scrotitis; oscheitis
- 纖維 : fibre; staple; filamentary
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Cystic fibrosis is caused by mutations in the gene encoding an ion - transport protein, the cystic - fibrosis transmembrane conductance regulator ( cftr ). defective secretion of anions is the primary cause of many of the clinical manifestations of cystic fibrosis, including pancreatic insufficiency
囊性纖維化是由作為陰離子通道的跨膜電導調節器（ cftr ）的基因突變所致，而陰離子分泌缺損是囊性纖維化的多種臨床表現（包括胰腺功能缺陷）的主要原因。The research team of prof chan hsiao chang, director of the epithelial cell biology research centre, in collaboration with zhejiang academy of medical sciences, demonstrated that cystic fibrosis transmembrane conductance regulator cftr is involved in transporting bicarbonate into sperm, and thus, is vital to sperm fertilizing capacity and male fertility. cftr is an anion channel, mutations of which cause cystic fibrosis, a disease characterized by defective cl - and hco3 - transport with clinical manifestations in a number of organ systems
由陳小章教授領導的香港中文大學上皮細胞生物學研究中心的研究人員，與浙江醫學科學院合作，證實囊性纖維化跨膜電導調節器（ cftr ）負責輸送碳酸氫根進入精子，對精子授精能力及男性生育能力非常重要； cftr是一個陰離子通道，其基因突變會導致囊性纖維化，因為氯離子和碳酸氫根（ hco3 - ）分泌缺陷，引發一系列器官病徵。The newly identified gene, nyd - sp27 has structural similarity to an isoform of phospholipase c. nyd - sp27 was expressed endogenously in human pancreatic - duct cells and upregulated in cystic fibrosis. researchers has proved that suppression of the gene resulted in augmentation of phospholipase - c - coupled calcium - ion release and protein kinase c activity, improvement in the amount of mutated cftr reaching the plasma membrane, and thus restoration of pancreatic anion secretion
Nyd - sp27內源性表達在人體的胰腺導管上皮細胞，並在囊性纖維化時表達增高，顯示該基因可能與病變有關。研究人員發現通過抑制該基因在人體囊性纖維化胰腺導管細胞中的表達，可以糾正缺陷的胰腺陰離子分泌。
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