bispecific antibody 中文意思是什麼
-
The bispecific antibody tilers of ascites fluid and culture supernatant of 3 - hn are 1 : 16000 and 1 : 64. at the same time the anti - p24 antibody and the anti - human rbc type a antibody in the ascites fluid of hybrid - hybridoma 3 - hn are tested, and their titer is 1 : 800 and 1 : 16000 respectively
為89士9條j十； ；的腹水型和上清型雙特異性抗體的效價分別為1 ： 16000和1 ： 64 ，同時測定腹水型抗體抗p24抗體活性及抗人a型紅細胞凝集抗體活性，效價分別為1 ： 800和1 ： 16000 。 -
2 - e4 - a and 82 - 6 are hybridized during their log growing time, and the hybrid - hybridomas are cloned for 3 times and produce 6 hybrid - hybridoma cells. the chromatosome of hybrid - hybridoma 3 - hu and hybridoma 2 - e4 - a and s2 - b are counted, and the antibody of ascites fluid or culture supernatant of 3 - hn is prepared. the positive clones are detected by three methods at the same time : rbc agglutination for monospecific anti - human rbc type a antibody, indirect elisa for anti - p24 antibody, and rbc solid - phase adherence for bispecific antibody
選其中一株3 - h _ （ 11 ）做雜交-雜交瘤細胞染色體計數，同時計數兩母株2 - e _ 4 - a和s _ 2 - b的染色體數：制備腹水型和上清型抗體，用三種方法同時檢測其中的雙特異性抗體、單特異性抗人紅細胞抗體和抗p24抗體，即紅細胞固相吸附法測雙特異中文摘要性抗體，紅細胞凝集試驗測單特異性抗人a型紅細胞抗體，間接elisa法測抗p24抗體；用腹水型抗體做耐熱性及耐凍融實驗。 -
This bispecific antibody companied with another anti - p24 monospecific monoclonal antibody can build a new way of indirect rbc agglutination to detect p24 antigen, and this new way is preliminarily applied to detect serial diluted p24 to determine the sensitivity
用雙特異性抗體致敏人a型紅細胞做指示劑，以抗p24單特異件單克隆抗體9a7做交聯劑，建立間接血凝檢測p24抗原的新方法，並初步應用於檢測系列稀釋的p24抗原以確定測定的敏感性。 -
Therefore the hybrid - hybridoma can secrete not only bispecific antibody but also anti - human rbc type a monospecific antibody and probably anti - p24 monospecific antibody. the mixed antibodies purified by ammonium sulfate is further purified by p24 affinity chromatography. the unsp
這樣，分離出雙特異性抗體，並證實雜交雜交瘤除分泌抗p24和人紅細胞的雙特異性抗體外，還分泌抗p24單特異性抗體和抗人a型紅細胞單特異性抗體。 -
The ascites fluid antibody purified by 33 % ammonium sulfate is further purified by chromatography. the p24 affinity chromato - graphic column done to purify the bispecific antibody is in the brcn activated sepharose 4b. after washing the unspecific proteins, change the washing buffer and the anti - p24 / anti - human rbc type a bispecific antibody and the anti - p24 monospecific antibody are gained respectively
方法是先用硫酸綏鹽析，再過親和層析柱，即33飽和硫酸按沉澱后，透祈過夜，上p24抗原做配體的濱化氰活化的sepharose4b柱，流洗掉雜蛋白和抗人紅細胞單特異性抗體后，再洗脫並收集雙特異性抗體。 -
To answer this question, a bispecific, trifunctional antibody constructs which can not only target block virus incorporated rca, but also can induce complement activation by it ' s fc fragment were designed and constructed and iv the role of this kind of bispecific antibody in virus neutralization was studied. 1. to test our idea, human immunodeficient virus ( hiv ) and enveloped extracellular virus ( eev ) of vaccinia virus ( vv ) were selected in our study because of their complex immune evasion stratiges, their threaten to humans, and because both these two kinds of virus can escape complement attack by incorporating host rca into their envelope
以嚴重危害人類健康，且具有復雜免疫逃避機制的有包膜的hiv病毒及痘苗病毒的eev病毒為研究對象，首先對它們逃避補體攻擊的現象進行了驗證，探討了宿主膜補體調節蛋白cd55 、 cd59與hiv病毒及eev病毒免疫逃避的關系，評價了病毒結合的這兩種補體調節蛋白作為本研究提出的，通過消除病毒逃避補體攻擊的機制來恢復病毒對補體攻擊的敏感性，提高補體抗病毒效率這一抗病毒策略的靶點的可能性。 -
This means when the bispecific antibody binds to healthy tissues away from light, it cannot activate t - cells, resulting in far fewer side effects
這就是說，當雙功能抗體與遠離光線的健康組織結合時，它不會激活t細胞，這樣就極少由副作用。 -
Fortunately, recently widely used bispecific antibody technique provided us a good model for target rca blocking for it ' s dual antigen binding activity and for the availablity of high
為了進一步探討用基因工程的方法制備抗病毒雙特異性抗體的可能性，我們又在現有的條件下構建、表達了 -
Objection : this study is to prepare a kind of bispecific antibody of anti - hiv p24 antigen and anti - human rbc type a antigen, and to build a new way to detect hiv p24 antigen with this bispecific antibody
目的：制備抗hivp24和抗人a型紅細胞雙特異性抗體，建立檢測hivp24抗原的新方法。
分享友人