phospholipase d 中文意思是什麼
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Spla 2 can significantly inhibits egf - induced egf receptorautophosphorylation, which also resulted in the inhibitionon egf - induced phospholipase d activation and tyrosine phosphorylation of phospholipase c - g 1. under the same condition, spla 2 can induce intracellular ceramidegeneration. moreover, exogenous ceramide analogs can also significantly inhibit such biologicalevent induced by egf, suggesting that ceramide may play an important role in spla 2 - induced cell death and the signaling events
在相同的條件下，分泌型磷脂酶a亦能誘導細胞內神經酰胺生2成的增加；外源性的神經酰胺類似物也能有效的抑製表皮生長因子誘導的這些生物事件，提示神經酰胺在分泌型磷脂酶a所介導的細胞死亡和信號傳導事件2中起著重要的作用。 -
Both spla 2 and ceramidehave been shown to inhibit bradykinin -, and pma - induced phospholipase d activation. these results indicated the existence of a subtle intertwined regulatory interaction between intracellular phosphoglycerol lipids and sphingolipids signaling pathways. in addition, we also found that spla can 2 down regulate theepidermal growth factor ( egf ) receptor activation
此外，我們還發現分泌型磷脂酶a能下調表皮生長因子受體的活化，它能明顯的抑製表皮生長因子誘導2的受體自身磷酸化，並抑製表皮生長因子誘導的磷脂酶d活性和磷脂酶c - g的1酪氨酸磷酸化。
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