phospholipase kinase 中文意思是什麼
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This response was mediated by gi and subsequent activation of phospholipase c ( plc ), which triggered two pathways : protein kinase c ( pkc ) led to repulsion, and inositol 1, 4, 5 - triphosphate ( ip3 ) receptor activation led to attractive turning
信號轉導機制的研究表明， sdf - 1和baclofen激活了生長錐表面的g蛋白耦聯受體，通過gi將信號傳遞給plc ，進而激活pkc和ip3信號通路。 -
The newly identified gene, nyd - sp27 has structural similarity to an isoform of phospholipase c. nyd - sp27 was expressed endogenously in human pancreatic - duct cells and upregulated in cystic fibrosis. researchers has proved that suppression of the gene resulted in augmentation of phospholipase - c - coupled calcium - ion release and protein kinase c activity, improvement in the amount of mutated cftr reaching the plasma membrane, and thus restoration of pancreatic anion secretion
Nyd - sp27內源性表達在人體的胰腺導管上皮細胞，並在囊性纖維化時表達增高，顯示該基因可能與病變有關。研究人員發現通過抑制該基因在人體囊性纖維化胰腺導管細胞中的表達，可以糾正缺陷的胰腺陰離子分泌。
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