phospholipase c 中文意思是什麼
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This response was mediated by gi and subsequent activation of phospholipase c ( plc ), which triggered two pathways : protein kinase c ( pkc ) led to repulsion, and inositol 1, 4, 5 - triphosphate ( ip3 ) receptor activation led to attractive turning
信號轉導機制的研究表明， sdf - 1和baclofen激活了生長錐表面的g蛋白耦聯受體，通過gi將信號傳遞給plc ，進而激活pkc和ip3信號通路。 -
Pretreatment with the phospholipase c inhibitor u73122 ( 5 umol / l ) significantly inhibited the il - 2 - induced depression of contraction. conclusion : it is concluded that the effect of il - 2 on contraction of ventricular myocytes is mediated via the cardiac k opioid receptor, and the post - receptor signal transduction pathway includes a ptx sensitive g protein and phospholipase c. 2 effect of interieukin - 2 on intracellular calcium tran
5 200u ffil ）濃度依賴性地降低單個心室肌細胞電刺激誘導的鈣瞬變幅度，使舒張末鈣水平升高； （ 2 ） il 2 （ 200u ml ）使咖啡因誘導的肌漿網內貯鈣的釋放降低： （ 3 ） 50偷i熱失活！ -
Spla 2 can significantly inhibits egf - induced egf receptorautophosphorylation, which also resulted in the inhibitionon egf - induced phospholipase d activation and tyrosine phosphorylation of phospholipase c - g 1. under the same condition, spla 2 can induce intracellular ceramidegeneration. moreover, exogenous ceramide analogs can also significantly inhibit such biologicalevent induced by egf, suggesting that ceramide may play an important role in spla 2 - induced cell death and the signaling events
在相同的條件下，分泌型磷脂酶a亦能誘導細胞內神經酰胺生2成的增加；外源性的神經酰胺類似物也能有效的抑製表皮生長因子誘導的這些生物事件，提示神經酰胺在分泌型磷脂酶a所介導的細胞死亡和信號傳導事件2中起著重要的作用。 -
The newly identified gene, nyd - sp27 has structural similarity to an isoform of phospholipase c. nyd - sp27 was expressed endogenously in human pancreatic - duct cells and upregulated in cystic fibrosis. researchers has proved that suppression of the gene resulted in augmentation of phospholipase - c - coupled calcium - ion release and protein kinase c activity, improvement in the amount of mutated cftr reaching the plasma membrane, and thus restoration of pancreatic anion secretion
Nyd - sp27內源性表達在人體的胰腺導管上皮細胞，並在囊性纖維化時表達增高，顯示該基因可能與病變有關。研究人員發現通過抑制該基因在人體囊性纖維化胰腺導管細胞中的表達，可以糾正缺陷的胰腺陰離子分泌。
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