telomere 中文意思是什麼

telomere 解釋
端區（端粒）
  1. Expression of telomere regulating factor tankyrase in gastric adenocarcinoma

    在胃腺癌中的表達
  2. Introduction telomerase is a ribonucleoprotein reverse transcriptase that synthesizes telo - meric dna sequences using its rna as template. it can remedy the loss of te - lomere after cellular mitosis, maintain telomere length and stabilize chromosome

    前言端粒酶（ telomerase ）是一種核糖核蛋白逆轉錄酶，能以自身的rna為模板，從頭合成染色體末端的端粒dna ，彌補細胞分裂時端粒dna的丟失，維持端粒的長度並穩定染色體。
  3. Telomerase is a ribonucleoprotein complex ( rnp ) composed by its rna component and protein subunits. telomerase can synthesize telomeric dna onto chromosomal ends using its own rna component as a template, elongate the length of telomere, increase cell life and even induce cell immortalization

    端粒酶（ telomerase ）是由端粒酶rna和蛋白質組成的一種核糖核蛋白復合物（ rnp ） 。端粒酶含有引物特異識別位點，能以自身rna為模板，逆轉錄合成端粒dna並加到染色體末端，使端粒延長，從而延長細胞的壽命甚至使其永生化。
  4. The telomere reserve of neonatal stem cells suffices for about a decade, judging from the age of onset of dyskeratosis congenita a disease associated with inadequate telomere maintenance

    從先天性角化不良癥（一種端粒維護不當的相關疾病）發作年齡來判斷，新生兒的幹細胞端粒儲備足夠滿足約10年。
  5. Telomere of yeast is rich in g and a that is ideal target of mms

    酵母端粒末端序列富含g和a ，是mms作用的主要靶點。
  6. Other chromosome elements, telomere and ars, have also been cloned for constructing artificial chromosome. arabidopsis telomere was cloned from pcr products using telomere repeat primers without other template. a 2000bp fragment of ars was released from arabidopsis genomic bac clone t14a4 by claidigestion and subcloned into clai digested pbluescript

    擬南芥的端粒是利用端粒的重復序列進行無模板的pcr擴增得到的；約2000bp的ars片段是從擬南芥的bac克隆t14a4中用限制性內切酶c1a1切下，然後亞克隆到通用載體pbluescript上。
  7. Objective through measure telomere length ( mean length of telomere restriction fragment, trf ) of dermal and intramuscular, and study it ' s length correlating with the different human " s age. the trf was examined by southern blotting. the formula to age estimating was obtained by regression analysis between the trf and the age

    目的應用southern雜交技術，對皮膚、肌肉端粒dna片斷長度（ meanlengthoftelomererestrictionfragment ，簡稱： trf ）進行觀察，測定不同年齡段人群的端粒dna片斷長度值，以期初步探明不同年齡段人群的端粒dna片斷長度的變化規律，繪制出端粒dna片斷長度值隨年齡變化的標準曲線，比較性別、籍貫對端粒dna片斷長度的影響，以期為法醫實踐工作中對無名屍體年齡推斷提供理論依據。
  8. Overall, the study participants had an average telomere loss of 21 nucleotides ( structural units ) per year

    總的來說，該項研究的參與者每年平均損失21個核甘酸（結構單位） 。
  9. Discussion the ends of linear chromosomes are protected by telomeres that consist of double - stranded repetitive sequences complexed with specific telomere - binding proteins

    討論端粒由雙鏈重復序列dna及特異的端粒結合蛋白組成，能保護線性染色體的末端。
  10. Therefore mms has potential function of damaging yeast telomere

    因此， mms有潛在損傷酵母端粒結構的作用。
  11. Telomerase is at end of the telomere, it helps to keep the sequence of dna, to offset or postpone the continuously shortening of the telomere while the cell division takes place

    端粒酶位於端粒末端，作用是合成端粒dna序列，以抵消或延緩端粒隨細胞分裂的不斷縮短。
  12. " such a relationship between leukocyte telomere length and physical activity remained significant after adjustment for body - mass index, smoking, socioeconomic status and physical activity at work, " the authors wrote

    「在對身體質量指數、吸煙、社會經濟狀況以及工作時的身體活動等因素進行調整后，白血球端粒和身體活動之間的這種關系依然明顯， 」這位作者寫道。
  13. The pot1 ( protection of telomeres ) protein binds the singlestranded overhang and is required for both chromosomal end protection and telomere length regulation

    Pot1蛋白與單鏈的突出端結合併被認為是保護染色體末端和調節端粒長度所必需的。
  14. In the former situation, 5s is near the telomere

    前一情況， ssn3na位於臂的遠端。
  15. Hence, permanent abolition of telomere elongation - - throughout the body - - might have no serious side - effects for about a decade, except on male fertility

    因此，全身端粒加長的永久廢除大約10年內沒有什麼嚴重副作用（雄性生殖力除外） 。
  16. This may be because of a residual telomere maintenance capacity stimulated by the genomic instability that having short telomeres confers

    這可能是由於殘余的端粒維持能力被基因組不穩定性（賦予短的端粒）所刺激。
  17. Expression of human telomere repeat binding factor1 in acute leukemia cells and its correlation with telomerase activities

    人端粒重復序列結合因子在急性白血病細胞中的表達及與端粒酶活性的關系
  18. Such cells could potentially give rise to cancers - - especially when they became functionally impaired by short telomere length - - but the progression of such cancers would be minimal because no telomere elongation system could be activated even by hypermutation

    這樣的細胞可能潛在地會長癌（特別是因端粒短而使它們的功能受到削弱） ，但這樣的癌癥進展是微不足道的，因為沒有端粒延長系統可以被激活（哪怕是高突變率也不能激活） 。
  19. Telomerase is a celler reverse transcriptase which catalyzes the synthesis and extension of telomeric dna. telomerase activation is not observed in normal tissues of somatic origin but in almost 90 % of human cancer, with the result the telomere shorten progressively with cell division and thus is a critical step for multistep carcinogenesis

    正常人體細胞（非生殖細胞）中端粒酶活性的表達很低，或用目前的方法幾乎檢測不到，而在90以上的惡性腫瘤中可檢測到端粒酶活性，相應的良性腫瘤則為陰性或僅有少數陽性。
  20. Can telomerase and alt both be eliminated without deleterious effects on the cell or tissue that are independent of telomere length

    端粒酶或alt二者都能被排除而對不依賴于端粒長度的細胞或組織無不良效應嗎？
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