前肽 的英文怎麼說

中文拼音 [qiántài]
前肽 英文
propeptide
  • 前 : Ⅰ名詞1 （在正面的） front 2 （次序在先的） first; top 3 （過去的; 較早的） ago; before; preceding...
  • 肽 : 名詞[化學] （有機化合物） peptide
  1. The contents of this studies include : 1 ) according to the researches on the correlation between the function and structure of the cmiv from bombyx - moxi before by others, especially by lixinlal in naigin normal university of china, we have designed and sythesized the mutation i of the gene of cmiv that was different from the natural cmiv about 50 % in amino sequence, using the favorable condon of the ecoli. after cheked the result of synthesis by sequence, we have cloned the gene into 3 " of the gene of thioredoxin in the thio - fusion expression vector ( ptxfus ), and the fusion protein of thio - cmiv was highly expressed in soluble form

    本研究的內容包括：一、在前人對抗菌肽cmiv研究的基礎上，對n端和c端進行氨基酸保守變換，設計和合成了該基因，充分使用大腸桿菌偏愛的密碼子，並將該基因5端與硫氧還蛋白基因3端融合，通過ptxfus表達載體獲得較高可溶性表達（在15 sds - page膠上可見明顯的表達蛋白帶） 。
  2. The formed ca - h radicals lead to the variations of the dihedral angles and. thus verified our own hypothesis. as for the calculation of small molecule ' s c - h bde, density functional theory ( dft ) b3lyp is employed

    量子化學計算表明，多肽鏈的ca - h的解離焓（ bde ）較小，易抽氫，且抽氫前後多肽鏈構象發生了很大的變化，這可以從構象角、的變化看出，從而從理論上驗證了我們的觀點。
  3. The changes of these endopeptidase are different during the former vasing of " samatha " and " belami ". the main eps in petals of " samatha " are the acid thiol - proteinase, metallo - proteinase and the alkali serine proteinase and the main eps in petals of " belami " are the acid thiol - proteinase and serine proteinase. during the later vasing the acid metallo - proteinase and the alkali serine proteinase become main eps in petals of " samatha " and " belami "

    這3種內肽酶在兩種切花瓶插初期（盛開以前）的表現不同： 『薩蔓莎』花瓣中以酸性金屬蛋白酶、巰基蛋白酶和堿性絲氨酸蛋白酶起主要作用， 『貝拉米』花瓣以酸性巰基蛋白酶、絲氨酸蛋白酶起主要作用，後期『薩蔓莎』和『貝拉米』花瓣均以酸性金屬蛋白酶、堿性絲氨酸蛋白酶起主要作用。
  4. The separation and preparation of the formica rufa linnaeus samples by reversed - phase high - performance liquid chromatography. in this part, the author has sequentially seperated the above mentioned components by reversed - phase high - performance liquid chromatography. as the result, each component is separated and prepared to get three components by this experimentation

    紅褐林蟻樣品的反相高效液相色譜分離、制備本部分利用反相高效液相色譜把前面所得的兩個組分繼續進一步分離，每個組分分別分離、制備各得到了三個組分，共六個組分；經紫外檢測方法檢測，結論為所得組分為多肽蛋白質。
  5. 2. the sequence of si gene from ibv - lx4 strain was consisted of 1614 bp from initiation codon atg to the possible cleavage site of spike glycoprotein, encoding for a 18 - amino signal - peptide with the n terminus of si protein and a polypeptide of 537 - amino acids. 19 highly conserved, potential glycosylation sites and 17 cysteines residues were characterized with si protein, homology analysis showe that there were gene deletion -

    S1基因：其全序列共1614bp （從起始密碼子atg到s前體蛋白裂解位點） ，編碼537個氨基酸，其氨基端有一編碼18個氨基酸的信號肽序列，第12 13位氨基酸殘基構成了信號肽的切割位點， 14 19位與111 124位氨基酸殘基為s1蛋白的跨膜區域。
  6. This paper introduces their mechanism, function and clinical research, illustrates their advantages compated with heparin, believing that both hirudin and hirulog are new promising antithrombotic agents

    本文介紹了他們的作用機理及其臨床研究，敘述了他們與肝素相比的優越之外，認為水蛭素與水蛭肽是兩類非常有前途的抗栓新藥。
  7. They are involved both in the production of mature proteins, acting as processing enzymes, and in the degradation of damaged or non - functional proteins [ 1 " 8l in plant plastids, proteases function in protein degradation seem to act to adjust the stoichiometry of subunits in supramolecular complexes, as well as to regulate the stoichiometry between different supramolecular complexes in response to environmental changes and process the nuclear - encoded preproteins in the stromal

    除了在相關蛋白質轉錄和翻譯方面的調控外，專一降解這些蛋白的蛋白酶活性以及轉錄翻譯量的上升也會加強對這些蛋白質的降解。雖然到目前為止對光系統中蛋白酶的了解尚且不如對光系統中各種多肽以及蛋白色素復合體的了解，但是對類囊體和葉綠體中蛋白酶的研究已經進展到相當深度了。
  8. Design of a novel macrocyclic sulfonamide peptidomimetics and synthesis of the precursors

    新型大環磺酰胺肽模擬物的設計及其關鍵前體的合成
  9. Injected group, 0. 1 % saccharin ( 1. 5 ~ 2ml / rat, in 5min ) intraoral infused group and cta group. the expression of endogenous leucin - enkephalin ( lek ) in the rat brain was observed and 5 parts of the thalamus including laterodorsal thalamic nucleus ( ld ), lateral part of mediodorsal thalamic nucleus ( mdl ), ventroposterolateral thalamic nucleus ( vpl ), ventroposteromedial thalamic nucleus ( vpm ) and reticular thalamic nucleus ( rt ) were comparatively researched before and after the acquisition of cta applying lek - immunocytochemistry. in behavioral experiment, 18 adult male sd rats were divided into normal cta group ( control ) and 2 naloxone i. p

    為探討cta形成過程中enk的作用，本實驗用成年雄性sd大鼠35隻，分為空白對照組、生理鹽水（ 2體重）腹腔注射組、 0 . 15mlicl溶液（ 2體重）腹腔注射組、 0 . 1糖精溶液口腔灌流組（ 1 . 5 - 2ml只， 5min ）和cta建立組，採用免疫細胞化學方法，觀察了亮腦啡肽（ lek ）陽性神經元在大鼠腦內的分佈情況，並比較了各組大鼠丘腦外側背核（ ld ） 、丘腦內側背核外側部（ mdl ） 、丘腦腹后外側核（ vpl ） 、丘腦腹后內側核（ vpm ）以及丘腦網狀核（ rt ）等5個腦區內lek表達水平的差異；另外將成年雄性sd大鼠18隻，分為正常cta建立組以及在cta建立前或cta建立后阿片受體拮抗劑納洛酮（ 2mg kg體重）腹腔注射組，對內源性阿片樣物質對于cta建立和保持的影響進行了行為學研究。
  10. Conformation analy / e of ptsp in dmso - d6 with nmr spectra in the dissertaion, ptsp was obtained by sollid phase method. its solution in dmso - d6 was examined by 2d nmr technique

    抑前胸腺肽溶液構象的nmr研究本文利用500mhz的nmr研究了ptsp在dmso - d _ 6溶液中的構象。
  11. Dissecting the prothoracic glands, by using silkworms " prothoracic glands in vitro culture and h - ecdysteroid - radioimmunoassay, the biological activities of those analog peptides were examined, and their active features, chemical parameters, as well as the relationship between structures and functions of those peptides were analyzed and compared. with an exception of 899808 having the sequence of awqdlsaw that affected like bom - ptsp, 899805 ( awqdlns ) and 899809 ( awqdlnsgaw ) partially stimulated ecdysteroidogenesis in a dose dependent manner, whereas 899803 ( dlnsaw ), 899804 ( awqdlnsa ), 899806 ( awqdln ) as well as 899807 ( awqdlnsawa ) had both stimulatory and inhibitory effects on ecdysteroidogenesis, depending on the concentrations

    研究結果表明，類似多肽89980呂（ awq uawaw ）的生物學功能與抑前胸腺肽的相同而且活性近似：類似多肽899805 （ awqdlns ） 899809 （ awqdlns … ）對家蠶前胸腺蛻皮激素的生物合成表現出隨濃度增加而增加的促進作用，而低濃度下幾乎不促進； 899803 （ dlnsawawl899804 （ awqdmsa ） 、 899806 （ awqdln ）和899807 （ awqdlnsawa ）類似多肽對家蠶前胸腺蛻皮激素的生物合成的促進和抑制作用與它們的濃度有著依賴關系。
  12. A approximately 460bp dna fragment was amplified by pcr from lactococcus lactis nizo r5 genome. the primers used in this study comprised the following nucleotide sequences : 5 " - cgcgaattcgatataggtttattgagt - 3 " and 5 " - atgaagcttatccatgtcagaactaa - 3 ". conditions used for the pcr consisted of 30 cycles of 94 ? for0. 5min, 45 ? for imin and 72 ? for 1. 5min, plus one additional cycle of 72 for 10min

    根據已發表的乳鏈菌肽前體基因的dna序列，設計兩條引物並引入酶切位點。以lactococcuslactisr5基因組dna為模板， pcr反應條件： 94變性30s ， 45退火60s ， 72延伸90s ，反應進行30個循環。成功擴出一條約460bp的dna片段。
  13. " the finding was unexpected and is consistent with the hypothesis that frequent tanning may be driven in part by a mild dependence on opioids, most likely endorphins, " said steven feldman, a professor of dermatology at the university. " the nausea and jitteriness induced by the medication are consistent with symptoms of mild opiate withdrawal.

    浸信醫學中心皮膚學教授斯蒂芬費德曼說： 「這個發現很令人意外，但剛好和之前的假設一致，那就是頻繁美黑也許是由於對如內啡肽等類鴉片藥物的微弱依賴造成的，而那些藥物引起的惡心顫抖也與缺少鴉片的狀況一致。 」
  14. Research on the insect brain neuropeptides and neuroendocrine system is one of the important fields of modem molecular biology, and is also a frontier field of beneficial insect utilization and biological pesticides development

    昆蟲腦神經肽和昆蟲神經內分泌系統（ neuroendocrinesystem ）的研究是現代分子生物學的重要領域之一，也是益蟲利用、害蟲生物防治的前沿研究領域。
  15. Dendritic cells ( dc ) is the most powerful apc, which can markedly increase the antigen - presentation capacity by maximizing the pepitide - mhc complexes on the cell surface and upregulating the co - stimulatory ligands b7 - 1 and b7 - 2, adhesion moleculees such as il - 12 that promote full activation of lymphocytes. full activation of antigen - specific t cells requires two signals - one signal coming via the tcr and the other signal through engagment of co - stimulatary molecules. t cells receiving one signal via their tcr are turned off by mhc ( major histocompatibility complex ), via t cell cd28 binding to b7 on the dc induce tlymphokine and t cell proliferatiion

    T細胞介導的細胞免疫在控制腫瘤生長方面發揮著重要作用， t細胞在發揮抗瘤效應（分泌細胞因子和直接殺傷）之前必須先經過活化，體內專職抗原提呈細胞（ apc ）細胞並使其活化，樹突狀細胞（ dendriticcell ， dc ）為t細胞的激活提供雙重信號， t細胞藉助tcr識別由dcmhc分子遞交的抗原肽后，通過tcr - cd3復合體傳遞抗原特異性識別信號（第一信號） ，以cd28為主的t細胞表面輔佐分子識別dc表面b7分子，傳遞非特異性協同刺激信號（第二信號） ，在機體抗腫瘤免疫應答中處于核心地位。
  16. Intraenous atrial natriuretic peptide ( anp ) improes cardiac sympathetic nere actiity ( csna ) and preents left entricular ( l ) remodeling in patients with first anterior acute myocardial infarction ( ami ), japanese researchers reeal

    日本研究人員揭示，靜脈內注射心房利鈉肽（ anp ）可以改善心臟交感神經活性（ csna ）並預防首發前壁心肌梗死（ mi ）患者左室重塑。
  17. At present, in an attempt to stimulate specific antitumor immunity, experimental models and clinical studies are currently evaluating the potent antigen - presenting capacity of dc combined with single or multiple tumor antigen epitopes. however, there are several problems in utilizing pulsing dc with synthetic immunodominant peptides from identified antigens. 1 ) the potential induction of tolerance ; 2 ) the need to determine the patient ' s hla haplotype, the limitation of therapy to patients whose tumors express defined specific tumor antigens in the context of the correct hla phenotype, the unavailability of peptides for all hla haplotypes ; 3 ) the lack of cd4 help cell - related epitopes for most antigens ; and 4 ) the ctl resulting from such protocols have a good in vitro capacity to kill peptide - pulsed target cells but only a modest capacity to kill tumor cells

    但是，學者們發現這一療法存在著如下的缺陷：單一ctl表位抗原肽的應用其抗腫瘤作用弱於多種腫瘤抗原的聯合應用，且有誘導免疫耐受的潛在危險，有時反而會促進腫瘤的生長；事先需對患者的hla單倍型進行鑒定，以確定ctl表位與hla單倍型是否匹配，目前尚缺乏能與所有hla單倍型相匹配的ctl表位，從而限制了這一療法的應用；這一療法所產生的ctl在體外能有效殺傷經腫瘤抗原肽共孵育過的靶細胞，但對腫瘤細胞的殺傷能力較弱：這種l表位抗原肽缺乏cd4汀h細胞相關的表位，因此，不能誘導有效的th細胞免疫應答。
  18. The single peptide of bt - r3 protein is a a helix which orients from inside to outside, and the transmembrane domain is also a helix which orients from outside to inside

    Bt - r3受體蛋白最前端的信號肽是一個由內向外a螺旋，跨膜區域（ tmd ）是一個由外向內的a螺旋。
  19. Our monthly capacity reaches 4, 000 purified peptides. it probably possesses one of the biggest capacity with state - of - the art facilities in custom peptide in the world

    目前，公司每月產量達到4000條純化肽，是目前中國多肽合成及純化規模最大品種最全的企業。
  20. The cdna sequence with 789 bp encodes an uncompleted open reading frame ( orf ) of 263 amino acids, which included a signal peptide of 18 amino acids, a proposed propeptide of 171 amino acids, a partial mature protein of 74 amino acids. the sequences of signal peptide and propeptide are very similar to ones from wannan agkistrodon acutus reported by fan chunyan, but it only contains partial amino acids of mature protein. the 800 bp is likely to be a part of gene encoding metalloproteinase agkistrodon acutus from guangxi province

    結論： 600bp產物和已報道的皖南五步蛇纖溶酶金屬蛋白酶氨基酸序列相比較，有90 . 6 %的同源性； 800bp產物中信號肽及前肽和已報道的皖南五步蛇金屬蛋白酶很相似，同源性為97 . 9 % ，但僅含有部分金屬蛋白酶成熟肽的氨基酸序列，推測此片段為廣< wp = 6 >西五步蛇金屬蛋白酶原基因的一部分。
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