核酸研究 的英文怎麼說

中文拼音 [hésuānyánjiū]
核酸研究 英文
nucleic acids research
  • 核 : 核構詞成分。
  • 酸 : 酸構詞成分。
  • 研 : 研同 「硯」
  • 究 : Ⅰ動詞（仔細推求; 追查） study carefully; go into; investigate Ⅱ副詞[書面語] （到底; 究竟） actually; really; after all
  • 核酸 : [生物化學] nuclein; nucleic acid核酸聚合酶 nucleic acid polymerase; 核酸酶 nuclease; 核酸內切酶 [生物化學] endonuclease
  • 研究 : 1. （探求） study; research 2. （考慮或商討） consider; discuss; deliberate
  1. A microdialysis study of excitatory amino acid levels of the monkey s caudate nucleus during the delayed go no - go task

    延緩go no - go任務操作中猴尾核興奮性氨基酸水平變化的微透析研究
  2. Chemotaxis mediated by chemokine receptors, such as cxcr4, play a key role in lymphocyte homing and hematopoiesis as well as in breast cancer metastasis. we have previously demonstrated that ? - arrestin2 functions to attenuate cxcr4 - meidated g protein activation and to enhance cxcr4 internalization. here we further show that expression of ( - arrestin2 in both hela and hek293 cells significantly enhanced the chemotactic efficacy of stromal - cell derived factor 1 ( ( sdf - 1 ( ), the specific agonist of cxcr4

    - arrestin2是趨化因子受體的一種重要的調節蛋白，本研究工作發現在hek - 293或hela細胞中升高- arrestin2的表達水平會顯著增強cxcr4介導的趨化作用，反之當- arrestin2的表達被它的反義核苷酸或rnai所抑制， cxcr4介導的趨化作用則被明顯抑制。
  3. It ' s meaningful to study the function of rab proteins in ciliates and further to explicit the mechanism of vesicular trafficking. the rob gene was amplified from macronuclear dna of euplotes octocarinatus. the size of gene was 783 bp long with an orf of 624 bp encoding eorabl protein and containing three in - frame tga codes

    本研究利用pcr技術從游仆蟲（ euplotesoctocarinatus ）大核dna中擴增出rab基因，並對該基因進行序列分析，該基因全長為783bp ，兩端為端粒序列，編碼框為624bp ，編碼207個氨基酸，開放讀框中有3個tga ，在此編碼半胱氨酸。
  4. Degenerate oligonucleotides to highly conserved regions of cucumis melo 1 - aminocyclopropane - 1 - carboxylic acid ( acc ) oxidase gene were used to prime the amplification of fragment of 128bp by ploymerase chain reaction ( pcr ) in samples of genomic dna from fruit of cucumis melo l. cv hetao flesh, which was cloned into plasmid vector pmd - 18 - t. the clon of antisense orientation were selected, and it was inserted downstream of camv35s promoter and enhancer " " of tmv into the plant expression vector pbinyxw, antisence expression vector pbinya was constructed. at the base that pollination and fertilization of cucumis melo l. cv hetao was studied, using pollen tube pathway transformate cucumis melo l. cv hetao, 76 fruit had been obtained, moreover, hardness and content of sugar were analysed

    本實驗以河套蜜瓜果肉基因組dna為模板，用甜瓜acc氧化酶基因特異寡核苷酸鏈為引物進行pcr擴增，得到128bp的擴增產物。將得到的擴增產物克隆到質粒載體pmd - 18 - t上，篩選反向克隆，然後將其反向構建到植物表達載體pbinyxw的camv35s啟動子和tmv增強子「 」的下游，構建成反義表達載體pbinya 。並在對河套蜜瓜授粉受精生物學研究的基礎上，通過花粉管通道法轉化河套蜜瓜，共獲76顆瓜，並進行了硬度和含糖量的分析。
  5. In this thesis, the development of emulsion polymerization theory and related new technologies are comprehensively reviewed, and the synthetic technologies of acrylate latex modified by organosilicon both at home and abroad are also reviewed. based on the current development and research in this field, attentions of this study are focused on three ways for preparing novel acrylate latexes modified by organosilicons, that is, 1 ) the acrylate monomers are copolymerized with unsaturated silicons by emulsion copolymerization ; 2 ) a new latex with microphase separation morphology is synthesized, which shows a core - shell structure character ; 3 ) soap - free polymerization is explored for preparing a higher - performance latex using an unsaturated silicon monomer, different acrylates and a reactive emulsifier. by using techniques of delaying addition of organosilicon monomer and a hydrolysis inhibitor, the hydrolysis and condensation of 3 - ( trimethoxysilyl ) propyl methacrylate during polymerization can be effectively prevented, as a result, organosilicon content in the macromolecular chain is increased

    同時採用有機硅單體延遲滴加及添加水解抑制劑等技術，有效防止了-甲基丙烯酰氧基丙基三甲氧基硅烷在乳液聚合過程中的過渡水解及縮合反應，提高了聚合物大分子鏈中有機硅鏈節的含量；利用紅外光譜與差示掃描量熱儀對產物分子結構進行了表徵，並通過對共聚產物力學和吸水率的測試，證實了本研究所制備的有機硅改性丙烯酸酯共聚物具有比純丙烯酸酯聚合物更優良的力學及耐水性能；從分子設計角度出發，利用醇解反應合成出水解、縮合反應速率較慢的兩種新型不飽和有機硅單體： ?甲基丙烯酰氧基丙基三乙氧基硅烷和?甲基丙烯酰氧基丙基三異丙氧基硅烷；利用核磁共振對新型硅烷單體結構進行了證實；研究表明利用新型硅烷單體可以制備出高硅烷含量的有機硅改性丙烯酸酯乳液，且其聚合產物具有較高的力學及耐水性能。
  6. Dna damages caused by so2 and lead acetate were studied with the single cell microgel electrophoresis technique ( or comet assay ) in order to confirm the damaging degree of lead ( as an important component of atmosphere particle matter ) on dna from male mice exposed to so2. the migrating distances of dna of brain, lung, spleen and kidney cells of mice increased significantly, compared to the control group under conditions of single and combined poisoning of so2 ( 42mg / m3 ) and lead acetate ( 0. 2 % ), and lead could strengthen dna damage degree by so2 in nuclear dna of brain, kidney, spleen cells. damaging degree of so2 on nuclear dna of lung cell of mice was more severe than that of lead

    為了明確大氣顆粒物中的重要組分? ?鉛在二氧化硫所致dna損傷中的作用程度，利用單細胞凝膠電泳技術（ singlecellgelelectrophoresis ， scge ，或稱彗星實驗， cometassay ）研究了鉛與二氧化硫的聯合污染，結果表明在42mg m ~ 3so _ 2和0 . 2醋酸摘要一abstract鉛單獨及聯合染毒條件下，小鼠腦、肺、腎、脾細胞dna遷移距離均比對照顯著增加;鉛加劇了50 :對腦、腎、脾細胞核dna的損傷程度; 50 :對肺細胞核dna的損傷程度要比鉛的損傷大，小鼠肺細胞核dna遷移距離在50 :和醋酸鉛聯合作用組與醋酸鉛單獨作用組間有極顯著性差異（ p < 0 . 01 ） ，而與502單獨作用組間沒有顯著性差異。
  7. Many advantages and principles of nucleic acid vaccine were reviewed in detail. the progress of its application and studies on malaria, schistosomiasis, cysticercosis and leishmaniasis were mentioned briefly

    本文較為詳細地敘述了核酸疫苗的優點、作用機理，簡略介紹了核酸疫苗在瘧疾、血吸蟲病、囊蟲病和利什曼原蟲病的應用與研究進展。
  8. G gene of rabies virus m, the of two main regions ( about 1000nt ), ranging from 3161nt to 4162nt and ranging from 4012nt to 4863nt of glycoprotein gene of rabies virus strain m, isolated from mouse in he nan, china were amplified by reverse transcriptase - polynerase chain reaction ( rt - pcr ) in order to complete glycoprotein gene of strain m. these regions were sequenced by the produce of pcr directly. comparison and analysis of nucleotide sequence and amino acid sequence deduced with that of other strains published was performed by computer with dnasisv 2. 5demo software

    本研究對我國河南某地野鼠體內分離的狂犬病野毒株mrv基因的3161位? 4162位（ 1001個堿基）和4012位? 4863位（ 851個堿基）片段進行了反轉錄pcr擴增和序列測定，得到mrv的糖蛋白基因全序列，用dnasisv2 . 5demo分析軟體，與已發表的代表性毒株g基因全序列進行核苷酸和氨基酸序列的比較分析，結果表明在同一基因型中， mrv和國際標準攻毒株cvs的同源性最高（ 96 . 5 ） ，和中國減毒株ctn的同源性最低（ 79 . 8 ） 。
  9. " for his work on nucleotides and nucleotide co - enzymes

    研究核苷酸和核苷酸輔酶
  10. These studies are helpful for elucidating the mechanisms of dna recognition and repair, and the design of novel synthetic nucleases

    此項研究會對闡明生物體內dna的識別修復機理、合理設計新的人工核酸酶提供理論指導。
  11. Researchers can figure out the evolutionary relations of opsins in the various classes of cones and from different species by examining the sequences of nucleotide bases ( or dna “ letters ” ) in the genes that code for these proteins

    透過比對視蛋白基因的核苷酸鹼基（或稱dna字母）序列，研究人員就能找出不同錐細胞視蛋白以及不同物種間視蛋白的演化關系。
  12. The best studied inducible and repressible enzyme in phytopathogenic prokaryotes is endo - pectate lyase in e. carotovora

    植物病原原核生物中研究得最清楚的是胡蘿卜軟腐菌的果膠酸內裂解酶。
  13. In this study, the meaningful results have been achieved, which is the important basic work to research the pili subunit vaccine of avian e. coli, and detect pila gene by nucleric acid probe. moreover, it is significant to research molecular epidemiology, to diagnose, to prevent and treat avian colibacillosis

    本研究為雞源致病性大腸桿菌菌毛基因工程疫苗的研究，制備核酸探針檢測pila基因提供了重要材料，對雞大腸桿菌病的分子流行病學研究、診斷和防治研究具有重要意義。
  14. The research development of single nucleotide polymorphism

    單核苷酸多態性研究進展
  15. Synthesis of riboflavin tetrapropanate by solid superacid sulphate ion on zirconium dioxide

    2催化合成核黃素四丙酸酯的研究
  16. This modification includes : ( 1 ) selecting two important molecules as candidates, ( 2 ) choosing a promiscuous t - cell epitope, and two b - cell epitopes or conserved amino acid sequences from the two important molecules, ( 3 ) connecting them adequately through analysis by the molecule designing software. therefore, the synthetic new antigen may interfere with the process of fertilization by multiple ways and its contraceptive effects may be enhancing. based on the molecule designing methods, the b - lymphocyte cell epitope of sperm / testis specific protein sp17 and cyritestin which interfere with fertilization in mouse, as well as the promiscuous th cell epitope of the ribonuclease ( rnase ) in bovine were selected

    本研究以蛋白質分子設計的理論和方法研究避孕疫苗，將sp17和cyritestin關鍵表位和牛核糖核酸酶非選擇性th細胞表位合理組合，獲得新抗原- 35肽序列；並在合成、純化後分別與弗氏佐劑、免疫刺激復合物（ iscoms ）混合后免疫不同遺傳背景的雌性小鼠，觀察血清和生殖道內的特異性抗體滴度的動態變化、生育力的改變以及免疫后小鼠重要臟器的組織病理學改變：以及在ivf下，新抗原的特異性抗血清對精卵相互作用的影響及抗原在精子表面的特異性定位。
  17. When using the nuclear acid sequence and the predicted amino acid sequence of scghr to blast the fugu genome, we found that there were two contigs which shared the most similarity with scghr. therefore we realized there maybe were two ghrs encoded by different genes in teleosts. then, by means of nuclear acid sequence joining, orf of fghr1 and fghr2 were predicted from fugu genomic sequences using cohoghr isf1, cohoghr isf2, chghr and other related ghr amino acid sequence available at ncbi database

    當利用南方鯰ghr的核苷酸、氨基酸序列blast東方?的基因組時，發現有兩個contig與其氨基酸序列非常相似，因此意識到魚類可能存在兩種不同基因編碼的ghr 。隨後主要利用已經克隆得到的cohoghrisf1 、 cohoghrisf2 、 chghr以及其他魚類ghr核苷酸和氨基酸序列blast東方純的基因組，採用序列拼接的方法從東方?基因組中分離出兩種不同基因編碼的fghr1和fghr2 （本研究把和傳統ghr相似的叫做ghr1 ，把另外一種叫做ghr2 ） 。
  18. Pka, receptor tyrosine kinase ( trk ) and classical nuclear receptor of gc were not involved in the gc " s activation of mapks the second part studied the nuclear translocation of gc activated mapks, mainly p38 and jnk, with laser confocal microscopy. the results showed that : 1

    Gc激活的mapks的激活不需要pka酪氨酸激酶受體trk及經典gc核受體的參與第二部分是研究gc激活的mapks的核轉位，主要是p38和jnk ，用激光共聚焦顯微鏡觀察到以下結果： 1
  19. Found the phenomenon observed in the nematode caenorhabditis elegans for the first time in 1998, consequently similar processes have been described for drosophila melanogaster, trypanosome, mammals including humans. the mechanism is that sirnas is the mediator, which can induce the risc to the target mrna and degrade it. recently there was great progress in the specific gene therapy and anti - virus, and rnai has been a focus of rna molecular therapy

    自1998年fire等在研究線蟲時首次發現以來，相繼在果蠅、渦蟲、錐蟲、小鼠及哺乳動物細胞中發現rnai現象。一般認為： rnai第四軍醫大學碩士學位論文效應作用機制是sirnaskmallinterferinguaduplex ）作為中介分于，引導risc （ rnaiinducingsuppresscomplex ）至靶基因m洲a處，隨后核酸內切酶將之降解。
  20. Advances in the research on fetal nucleic acids analysis from maternal plasma

    孕婦外周血中胎兒核酸研究進展
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