特異抗體 的英文怎麼說
中文拼音 [tèyìkàngtǐ]
特異抗體
英文
specific antibody- 特 : Ⅰ形容詞(特殊; 超出一般) particular; special; exceptional; unusual Ⅱ副詞1 (特別) especially; v...
- 異 : 形容詞1 (有分別; 不相同) different 2 (奇異; 特別) strange; unusual; extraordinary 3 (另外的;...
- 抗 : Ⅰ動詞1 (抵抗; 抵擋) resist; combat; fight 2 (拒絕; 抗拒) refuse; defy 3 (對等) contend with...
- 體 : 體構詞成分。
- 特異 : 1 (特別優異) exceptionally good; excellent; superfine2 (特殊) peculiar; distinctive特異功能 s...
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In view of the common property of dendritic cells and complement, namely their ability to link innate and acquired immunity, and with no reports, to date, addressing the direct effects of complement on the biological functions of dendritic cells, we decided to study the interaction between the complement system and dendritic cells
本研究的完成有助於在免疫應答的調控機制方面獲得新的認識,並對補體和dc在連接天然免疫和獲得性免疫之間的作用及相互關系能有更全面的理解,為進一步從新的角度和思路深入研究dc在抗原特異性免疫應答與免疫耐受中的作用及其機制奠定基礎。It has been demonstrated that complement activating and cr2 cross - linking on b lymphocytes set up a bridge between innate and acquired immunity. the interaction of c3 and cd21 on b lymphocytes will benefit initiating immune response and regulating primary antibody response. cd21 / cd35 is important in the process of antibody avidity maturing, this is critical to b lymphocyte activation especially in the state of low antigen concentration
現己證實補體的活化以及b細胞表面crz的交聯在先天和獲得性免疫之間架起了重要的橋梁,表現為c3與b細胞cdzi的相互作用有利於啟動抗體應答反應,並對初級抗體應答反應有調節作用: cdzi cd35對于抗體的親和性成熟具有重要作用,在抗原濃度低的情況下,對于活化b細胞是至關重要的,而且mlgm (交聯有利於特異的低親和性b細胞對t細胞依賴性抗原和t細胞非依賴性抗原產生免疫應答。On the other hand, there is substanial evidences tha dcs mediate tolerane. the gm - csf - stbolated mouse bone mwderived mhc class ii + dc progendors tha are deficient in cell surface erpression of the costbolatory molecules b7 - l and b7 - 2 can induce alloanginspecific t ceil anergy in vbo. systendc adchstraion of these donor - derived dc progendors to recipients intravenously 7 days before transplantation prolonged the median graft survival tane from 9. 5 days to 22 days wbout additional twnosuppressions in a mouse cardinc twlanation model
1995年, lul等報道表面缺乏共刺激分子,特別是缺乏cd80 ( b7 - 1 )和cd86 ( b7 - 2 )的未成熟型dc能在體外誘導同種抗原特異性的t細胞無能,而對dc的適當處理能夠使未成熟型dc潛在的耐受原性得以放大和增強,使得dc在誘導免疫耐受中具有相當重要的作用及潛在的應用價值。Compared with the known antibodies, the antiserum we prepared is highly specific and rules out the possibility of cross - reacting with angiotensin fragments. 4
與己有抗體相比,本實驗制備的抗agt多克隆抗血清不僅具有較高的特異性,而且排除了與血管緊張素短片段的交叉反應。This work produced large amounts of high - purity envelope protein antigens and envelope - specific antisera, and established detection systems for envelope antigens as well as antibodies
通過以上工作,得到了大量、高純的被膜蛋白抗原和被膜蛋白特異的抗血清,建立了被膜蛋白抗原、抗體的檢測體系。Anti - keratin auto antibody ( ak auto ab ) is accepted generally as a significant component of natural auto antibody ( naa ) which is found in human as well as vertebrate, and is of characteristic of polyreactivity, low avidity, extensive connectivity and shorting of specificity to the species
天然自身抗體( naa )廣泛存在於人和脊椎動物體內,具有多反應性、親和力低、締和性廣及種屬特異性差的特點。From dead chickens, one virrus was isolated by using eggs and chicken embryo fibroblast. lt was able to agglutinate chicken ' s erythrocytes and this heamagglutination could be inhibited by newcastle disease antiserum. this strain ' s biological property was tested by barren spot, cross - enutralization and cross - heamagglution inhibited and it was found that it was homological with the standard newcastle disease virus ( ndv ) virulent strain and avirulent strain but it had some diference with the standard strain
本實驗採用spf雞胚及雞胚原代成纖維細胞,從河北省某雞場新城疫免疫抗體很高的病死雞的腦組織中分離得到一株病毒。此株病毒能凝集雞的紅細胞,並且這種凝集可以被特異性抗血清所抑制。The target gene was then subcloned into plasmid vector and induced by iptg for its expression. after that, the recombinant protein was purified and used for the identification and characterization of its immunogenicity. the effect of the induced specific ige antibody on the hepatic granuloma formation and fibrosis after challenge infection with schistosome cercariae was evaluated
Niptg誘導表達,產物沉澱中於約45kda處顯見高合蛋白表達帶, westernblot分析表明,該蛋白帶可被篩庫血清中特異性lge抗體識別;而載體本身表達的26gst蛋白帶則否。However, the receptor and translocation domains of the colicin ia can only recognize the inner and outer membrane receptors of the escherichia coli, therefore the wild type colicin ia can not be developed into antibiotics against other types of bacteria
然而由於其信號識別結構域只能識別大腸桿菌外膜和內膜上的特異受體,因此野生型大腸菌素難以拓展成為對抗它種細菌的抗菌素。Confirmation is accomplished by demonstration of specific antibodies or by isolation studies.
特異性抗體的證明或病原分離可以用來確診。The child ' s skin is more delicate, fight cold ability inferior, some child usually arrive rarely outdoor activity, lack the capacity of counteractive chill, or because of certain idiosyncrasy, when coming in the winter, if carelessly heat preservation, with respect to incidental chilblain
小孩的皮膚比較嬌嫩、抗寒能力較低,有的小孩平素很少到室外活動,缺乏反抗嚴寒的能力,或因某些特異體質,冬天到來的時候,假如不注重保暖,就輕易發生凍瘡。Confocal microscopy observation followed immune - fluorescence staining with anti - gp130 showed that gp130 could interact with tle1 at the cytomembrane region. moreover, this interaction inhibited the concentration of tle1 into nucleus
為了進一步證實上述發現,我們表達並純化了gst - gp130胞漿區融合蛋白和gst - tle1獨特性片段融合蛋白,並制備了特異性抗tle1多克隆抗體。Second, ca - np30 conjugate was made by binding ca with np30. then immunized balb / c mice with ca - np30, and evaluated its effects on protective immunity, serum specific igg antibody levels and delayed type hypersensitivity ( judged by footpad test )
將鈣納米顆粒ca與np30制備成ca皿30結合物( ca np30 ) ,主動免疫b從b兒, j 、鼠,觀察其對, j 、鼠抗血吸蟲感染的保護作用、對血清特異性屹g抗體的影響和足墊反應。After giving birth to a child, give a new life for a short while inject is vaccinal or second liver is distinctive antibody
生了小孩后,第一時間給新生兒注射疫苗或者乙肝特異抗體。Studies of genes related to heart development in drosophila contribute to reveal the mechanisms of human heart development and the congenital heart diseases. to clone and identify new genes that control the heart development, by a way of chemical mutagen, ems, we have established 1, 200 balanced - lethal lines on chromosome 2 and 3. with the screening the 330 stocks with immunochemical method using heart - specific antibody, mab. no. 3, we detected 60 lethal lines showing heart mutant phynotype
為了克隆和鑒定控制心臟發育的新基因,本研究利用化學誘變劑甲磺酸乙酯大規模地誘變果蠅,並且建立了1200個第二和第三染色體的平衡致死系,利用心臟組織特異抗體mab . no . 3對其中330個品系進行免疫化學方法篩選,觀察到有60個致死系表現出心臟突變表型, 20個品系的心臟突變表型有待進一步證實。In the paper, with m4g3 monoclonal antibody to breast cancer prepared in our hospital previously, we have successfully accomplished the cloning and expressing of one specific antigen gene in breast cancer by construction of cdna library and screening techniques. we believe that it will provide reliable proof for clinical usage of this antibody and dependable evidence for profound establishment of the mechanisms in form ation and progression of breast cancer
本研究針對我院前期制備的一株乳腺癌單克隆抗體( m4g3 ) ,利用cdna文庫的構建和篩選技術,完成了此乳腺癌特異抗原基因的克隆與表達,為此抗體的臨床應用及進一步闡明乳腺癌發生、發展機制提供了可靠的依據。The expressive gene fragment was 333bp long. analyses of the tcr y fragment shpwed that it contained three epitopes. it was showed that specific anti - idiotypic antibody could be found since four weeks after the first immunization and came to the climate on the sixth week. the antibody titers of the same time were higher in group pcdna3 / tcr y - il - 2 than in group pcdna3 / tcr y ( po. 01 ). the highest antibody titer was 1 : 640 in the group pcdna3 / tcr y - il - 2, whereas the highest was 1 : 160 in the group pcdna3 / tcr y. there were mrna expression in skeletal muscle cell could be found in group pcdnas / tcr y and group pcdna3 / tcr y - il - 2 on fifth day after inoculation
用tcryvi獨特型dna重組載體作為疫苗免疫小鼠,結果表明pcdna3汀cry組及pcdna3廳cry ? il ? 2組小鼠1血肩中全部產生了特異性抗獨特ffo抗體,抗體滴度在第4周開始增高,第6周時達到高峰。在同一取血時間, w兒1 ry一幾一二組小鼠抗體滴度均高於pcdna3 tcry組( p 0 1 ) 。 pcd a3 tcry組小鼠抗體滴度最高達1 : 16小pc 。Natural autoantibody ( naa ) refers to antibodies that are present in the surum of healthy individuals in the absence of deliberate immunization with the targeted antigen. previous studies have showed that human immunity system includes a huge and complicated autoantibody repetoire. to date, several hundred naa have been found and proved to exist in normal individuals, including autoantibody targeted rbc, mhc, dna, transferrin, keratin, diphosphatidyglycerd, idiotype of igg, etc. naa, characterized by binding to various and nonspecific antigen, reacting rapidly, keeping conservative relatively, has been widely claimed to be an important constituted component of innate immunity. lt was proposed that the production of naa was related to positive selection of b lymphocytes
對naa的研究表明,健康人體免疫系統中存在著一個龐大而復雜的自身抗體網路。包括抗角蛋白自身抗體( antikeratinautoantibody , akautoab )在內,迄今已經發現並證實的naa有數百種,如抗rbc 、 mhc 、 dna 、轉鐵蛋白、脂類和多糖的抗體以及jerne免疫調節網路中的抗獨特型抗體( anti - idiotypeantibody )等。由於個體出生即有naa ,且naa具有作用范圍廣、沒有特異的選擇性、反應出現快、有相對的穩定性等天然免疫的特點, naa被認為是天然免疫( innateimmunity / naturalimmunity )的重要組成部分。Human or animal serum containing antibodies that are specific for one or more antigens
抗毒血清,抗毒素包含對一種或多種抗原的特異抗體的人體或動物血清Bleeds were taken from all mice 2 weeks after each immunization. then we assayed the influenza virus specific antibody and the ratio of igg1 to igg2a in mice serum
每次免疫后尾部采血,檢測血清中的流感病毒特異抗體和抗體中的iggi / iggza比值,以確定免疫反應的主要類型( thz / thl ) 。分享友人