特異精子抗原 的英文怎麼說
中文拼音 [tèyìjīngzikàngyuán]
特異精子抗原
英文
sperm-specific antigen- 特 : Ⅰ形容詞(特殊; 超出一般) particular; special; exceptional; unusual Ⅱ副詞1 (特別) especially; v...
- 異 : 形容詞1 (有分別; 不相同) different 2 (奇異; 特別) strange; unusual; extraordinary 3 (另外的;...
- 精 : Ⅰ形容詞1 (經過提煉或挑選的) refined; picked; choice 2 (完美;最好) perfect; excellent 3 (細)...
- 子 : 子Ⅰ名詞1 (兒子) son 2 (人的通稱) person 3 (古代特指有學問的男人) ancient title of respect f...
- 抗 : Ⅰ動詞1 (抵抗; 抵擋) resist; combat; fight 2 (拒絕; 抗拒) refuse; defy 3 (對等) contend with...
- 原 : Ⅰ形容詞1 (最初的; 原來的) primary; original; former 2 (沒有加工的) unprocessed; raw Ⅱ動詞(原...
- 特異 : 1 (特別優異) exceptionally good; excellent; superfine2 (特殊) peculiar; distinctive特異功能 s...
- 精子 : [生理學] sperm; spermatozoon (pl spermatozoa); spermium (pl spermia)精子活率 sperm motility r...
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This modification includes : ( 1 ) selecting two important molecules as candidates, ( 2 ) choosing a promiscuous t - cell epitope, and two b - cell epitopes or conserved amino acid sequences from the two important molecules, ( 3 ) connecting them adequately through analysis by the molecule designing software. therefore, the synthetic new antigen may interfere with the process of fertilization by multiple ways and its contraceptive effects may be enhancing. based on the molecule designing methods, the b - lymphocyte cell epitope of sperm / testis specific protein sp17 and cyritestin which interfere with fertilization in mouse, as well as the promiscuous th cell epitope of the ribonuclease ( rnase ) in bovine were selected
本研究以蛋白質分子設計的理論和方法研究避孕疫苗,將sp17和cyritestin關鍵表位和牛核糖核酸酶非選擇性th細胞表位合理組合,獲得新抗原- 35肽序列;並在合成、純化後分別與弗氏佐劑、免疫刺激復合物( iscoms )混合后免疫不同遺傳背景的雌性小鼠,觀察血清和生殖道內的特異性抗體滴度的動態變化、生育力的改變以及免疫后小鼠重要臟器的組織病理學改變:以及在ivf下,新抗原的特異性抗血清對精卵相互作用的影響及抗原在精子表面的特異性定位。This conceptual article describes our original thoughts of the future development of immunocontraceptives , preferably , based on immunoglobulins rather than vaccines , against human sperm specific antigens and seminal plasma immunosuppressive factors
本文描述就未來免疫避孕藥具開發的原始想法,最理想的避孕藥具可能是基於針對人類精子特異性抗原和精漿免疫抑制因子的免疫球蛋白。
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