等位基因連鎖 的英文怎麼說
中文拼音 [děngwèijīyīnliánsuǒ]
等位基因連鎖
英文
allele linkage- 等 : Ⅰ量詞1 (等級) class; grade; rank 2 (種; 類) kind; sort; type Ⅱ形容詞(程度或數量上相同) equa...
- 位 : Ⅰ名詞1 (所在或所佔的地方) place; location 2 (職位; 地位) position; post; status 3 (特指皇帝...
- 因 : Ⅰ動詞[書面語] (沿襲) follow; carry on Ⅱ介詞1 [書面語] (憑借; 根據) on the basis of; in accord...
- 連 : Ⅰ動詞1 (連接) link; join; connect 2 (連累) involve (in trouble); implicate 3 [方言] (縫) ...
- 鎖 : Ⅰ名詞1 (安在開合處使人不能隨便打開的器具) lock 2 (姓氏) a surname Ⅱ動詞1 (上鎖) lock up 2 ...
- 連鎖 : linkage; kettung; (山脈) catena; chain連鎖反應 chain reaction; circular reaction; circular resp...
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Restriction enzymes and dna probes are used to determine the exact sequence, but it is possible to get a rough estimate by analyzing the frequency of recombination between the alleles of linked genes
雖然可以利用限制性內切酶和dna探針精確的分析出特定序列,但是在分析連鎖基因等位基因間的重組序列時,會出現不準確的估計。Linkage analysis localizes a gene solely on the basis of its location, without regard to its biochemical function. transmission disequilibrium test ( tdt ) is one of the methods being used. the basic thought of tdt is : if the marker locus is in the neighborhood of the disease locus, then a specific marker allele associated with the disease allele will have higher frequency among diseased individuals compared to normal individuals
該檢驗統計量的基本思想是:若標識基因座在疾病基因座附近,那麼與疾病等位基因相關聯的標識等位基因將以更高的頻率出現在生病的個體中(相對正常體) ,這個關聯的標識等位基因相對于另一個標識等位基因的不平衡傳遞表明了標識基因座和疾病基因座之間存在連鎖。
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