粘連因子 的英文怎麼說
中文拼音 [niánliányīnzi]
粘連因子
英文
adhesion factor- 粘 : 粘動詞(粘附) glue; stick; paste; adhere to; bond
- 連 : Ⅰ動詞1 (連接) link; join; connect 2 (連累) involve (in trouble); implicate 3 [方言] (縫) ...
- 因 : Ⅰ動詞[書面語] (沿襲) follow; carry on Ⅱ介詞1 [書面語] (憑借; 根據) on the basis of; in accord...
- 子 : 子Ⅰ名詞1 (兒子) son 2 (人的通稱) person 3 (古代特指有學問的男人) ancient title of respect f...
- 粘連 : adjoin; adhesion; synechia; adhaesio; accretion; anchylo-; ankylo-; ancylo-
-
Studies revealed that p - catenin dissociated from ccc and translocated into free catenin pool in cytosol after it has been phosphorylated at tyrosine or serine residues, and in this situation, the ccc has been disrupted and cell adhesion function disturbed. a large amount of the free p - catenins in the cytosol can be degraded by the tumor suppressor apc, and the remains translocate into nucleus and bind to transcriptional factor tcf / lef in the nucleus and then promote cell proliferation related gene or anti - apoptosis gene transcription
當-連環蛋白酪氨酸或絲氨酸殘基磷酸化后,就與ajs發生解離而游離到細胞漿中,此時細胞的粘附功能也發生障礙,游離到胞漿中的-連環蛋白,一部分被抑癌因子apc降解,一部分則轉移到細胞核內,與核內的轉錄因子tcf lef結合,啟動與細胞增殖有關的基因轉錄。Levels of fasting blood glucose and 24h urinary microcontent of albumin 24 h malb were determined dynamically ; the serum glycosyl hemoglobin hba1c was determined after the last medication ; the ultrastructural changes of kidney were observed by transmission electron microscope ; the expressions of collagen, fibronctin, laminin ln, and the ecm metabolism influencing factors, including mmp2, tissue inhibitor of metalloproteinase timp2, transfer growth factor 1 tgf 1 in renal tissue were detected by immunohistological chemistry and image collecting analytical system
動態檢測各組大鼠空腹血糖fbg 24h尿微量白蛋白24h malb ,末次給藥后測定大鼠血漿糖化血紅蛋白hba1c透射電鏡觀察各組大鼠腎臟超微結構改變,應用免疫組化技術及圖像採集分析系統測定各組大鼠腎臟組織中型膠原c纖維連接蛋白fn層粘連蛋白ln的表達,測定影響ecm代謝的基質金屬蛋白酶2 mmp2基質金屬蛋白酶抑制劑2 timp2及轉化生長因子1 tgf 1的表達。There is a relationship between catenin phosphorylation, translocation and tumoregenesis, further more, in this relationship, cell signaling cascade and mitogen and their receptors are involved. base on these evidences, people are trying to disturb the key molecules in this signaling cascade for anti - tumor purpose
表皮生長因子( egf )能使p120 ~ ( ctn )酪氨酸磷酸化,磷酸化使bel - 7404細胞的粘附能力降低而遷移行為增強; p120 ~ ( ctn )在細胞內的分佈出現明顯的核內轉位, -連環蛋白也出現相似的變化。Cell adhesion to surface of the substrate is essential to development of the anchorage - dependent cells. only after adhering to surface followed by spreading can cells develop and proliferate. most synthetic polymers used as orthopaedic matrix substitute present hydrophobicity, which may correlates to the low degree of cell attachment. modification with cell adhesion protein / peptides can be benificial to the cell adhesion on polymers and then affect the cell proliferation and differentiation. cell attachment to substrate is primarily mediated by integrins, a widely expressed family of heterodimeric surface receptors. most extrcellular matrix proteins such as fibronectin, osteopontin, collagen type i, bone sialoprotein and vitronectin contain an arg - gly - asp ( rgd ) sequence which is specific to the fixation of cell membrane receptors like integrin. the main aim of this research is to measure, assess adhesion, proliferation of rabbit marrow stromal cells ( mscs ) on the polymers coated by fibronectin, collagen type i or biotie gen, which includes : ( 1 ) biologic characteristics of rabbit mscs were observed by two types of separating method in primary culture. ( 2 ) adhesion, proliferation and differentiation of mscs cultured on polymers coated with biotiegen were assessed. ( 3 ) also, adhesion, proliferation and differentiation of mscs were assessed on plga film or porous plga substrates coated with fibronectin, or collagen type i respectively. ( 4 ) bone formation was observed on the porous plga substrates coated with collagen type i in vivo. this research aims to give new way to make novel synthetic bone with cell adhesion and high bone induction capabilities
因此將這些蛋白包被、固定到材料表面,觀察骨組織工程種子細胞mscs細胞的粘附、生長特性是本研究的中心環節,並從以下方面進行探討: ( 1 )採用不同原代細胞分離方法,研究其對mscs細胞的生物學特性影響。 ( 2 )檢測基因勝肽膠對mscs細胞粘附、增殖及分化的影響。 ( 3 )分別採用型膠原及纖維粘連蛋白( fibronectin , fn )包被聚乙醇酸-乳酸共聚物( poly ( 1actide - co - glycolide ) , plga )膜及多孔塊型plga材料,觀察細胞在單層或三維培養狀態下,型膠原及fn對mscs細胞粘附、增殖及向成骨細胞分化效應及能力。By use of the stress free conditions on crack and the continuity conditions of stress and displacement on ideal bonded material interface, the stress field of an bi - material infinite plate with an elliptical inclusion and a deminfinite interface crack are given on the base of the complex potentials solutions obtained above. and the corresponding stress intensity factor k is given
在該復勢解的基礎上,根據裂紋表面的零應力條件和理想粘接界面上的位移和應力連續條件,通過求解hilbert問題,得到了含有夾雜和半無限界面裂紋的無限大板的應力場,並由此給出了裂尖的應力強度因子k 。The pcr products were purified and linked with pmd 18 - t vector respectively. the positive recombinants were selected and digested with double restriction enzymes respectively. goat fsh - a and p subunit genes which had sticky ends were purified and linked respectively with pf which also had the corresbonding sticky ends and were purified
將所得的山羊fsh - 、亞基基因分別用加相應限制性內切酶酶切位點的引物大量擴增,回收后與pmd18 - t連接,篩選出陽性重組子,大量雙酶切回收獲得帶粘性末端的山羊fsh - 、亞基基因,將它們分別與同兩個酶大量雙酶切回收獲得的帶粘性末端的pf質粒進行連接,篩選陽性重組子。分享友人