胞膜受體 的英文怎麼說
中文拼音 [bāomóshòutǐ]
胞膜受體
英文
cell-membrane receptor-
Comprehensive cellular responses was found in human amnion fl cells following exposure to low concentration of mnng, such as the lowering of dna replication fidelity resulted from alteration of dna polymerase profile ; activation of a lot of transcription factors, such as api, creb, nf - kb etc ; clustering of egfr ( epidermal growth factor receptor ) and tnfr ( tumor necrosis factor receptor ) and activation of camp - pka - creb and jnk / sapk signal pathways
我們發現,低劑量mnng處理后的人羊膜fl細胞有廣泛的細胞反應,並有多個信號轉導通路的激活和基因表達的改變。例如dna復制保真度下降, dna聚合酶譜發生改變,應用報告基因技術和底物磷酸化檢出技術證明細胞一系列轉錄因子如ap1 、 creb 、 nf b等被激活,細胞表面受體如表皮生長因子受體、腫瘤壞死因子受體發生聚簇,細胞信號轉導通路camp - pka - creb和jnk sapk被激活。Activation of rat liver microsomal glutathione s - transferase by chlorambucil and cyclophosphamide in vitro
高糖對人腎小球系膜細胞過氧化物酶體增殖物激活受體家族表達的影響This ion channel, present in the membrane of many nociceptors, responds not only to capsaicin, the pungent ingredient in chili peppers, but also to distressful heat and to protons ( the hydrogen ions that make substances acidic ) ; protons are unusually abundant in inflamed tissue
該受體是一種離子通道,出現在許多痛覺受器的細胞膜上,不只對辣椒的辛辣成份起反應,也對傷人的熱及質子(造成酸性的氫離子,在發炎組織中特別多)起反應。Translocation from endocytic compartments to the cytosol is the essential and rate - limiting step in the intoxication process of most toxins such as ricin, diphtheria toxin, shiga toxin and pseudomonas exotoxin ( pe ). a number of these toxins are transported to trans - golgi network ( tgn ), and in many cases such transport to the tgn is required for the translocation and cytotoxicity. in deed, 5 % of the ricin endocytosed by cells has been shown to reach the tgn
蓖麻毒素進入細胞的機理不甚明了,一般認為是rtb先與細胞膜受體結合,主要經過受體介導的內吞作用進入吞噬體,然後沿著內體、高爾基體、內質網等逆向分泌途徑,有序地運輸到內質網,最後從內質網轉位進入細胞漿,在胞漿內攻擊核糖體,從而抑制蛋白質的合成,導致細胞死亡。For example, the signal transduction of g protein - coupled receptor is mediated by g protein and can generate intracellular messages ; there exist some transmembrane proteins in the membrane of endoplasmic reticulum, and some of them are related with the synthesis and transportation of some proteins, while others are related with substance metablism, such as glucose - 6 - phosphatase ( g6pase ). in addition, after binding with the 7 - tm receptors affiliated to frizzled protein family, wnt can activated disheveled protein in cytoplasm which is essential to embryonic development
如g蛋白偶聯受體通過g蛋白介導產生胞內信使( camp , cgmp , dg , ip _ 3 )將胞外信號傳遞到胞內,從而引起生物學效應;內質網上也存在著一些跨膜蛋白,其中一些與蛋白質的合成及運輸有關,一些與物質代謝有關,如葡萄糖- 6 -磷酸酶。It consists of fusiform neurons with intensely expressed neuropeptides in the fibers, terminals, and neuronal somata. functional connections between the mrd and hippocampus, amygdala and the basal nucleus of meynert were identified by c - fos expression method [ 14 ]
Nmdar在谷氨酸中樞神經系統的許多功能上具有關鍵作用, nmda受體激活后可引起神經元細胞膜對na + 、 k +和ca2 +通透性增強,產生興奮性突觸后電位。Ip3 - ip3 receptor ( ip3r ) interaction mediates the release of ca2 + from the endoplasmic reticulum in response to many different extracellular stimulus. for higher plants, however, though it is now generally accepted that ip3 participates in signal transduction in many important cellular processes, only limited evidence is available for the presence and properties of the ip3r - like protein so far. here, using the immunological methods with an antibody raised against a mammalian inositol 1, 4, 5 - triphophate receptor ( type 1 ), we found that, 1 ) the antibody across - reacted the proteins with about 200kd in microsomes from oryza sativa and about 200kd from arabidopsis thaliana respectively
本實驗用sds - page電泳和免疫印跡的方法,用哺乳動物大鼠三磷酸肌醇受體的多肽做抗體對類三磷酸肌醇受體蛋白鑒定,結果表明:抗體與水稻和擬南芥微粒體蛋白分子量大約為200kd的蛋白交叉反應,同時還發現在水稻微粒體蛋白62kd和擬南芥微粒體蛋白45kd處有交叉反應的蛋白條帶存在,表明在植物中有類三磷酸肌醇受體蛋白的存在;用免疫膠體金方法,發現類三磷酸肌醇受體蛋白主要分佈於液泡膜和細胞質膜上。These interactions are primarily dependent upon the coordinated actions of ovarian progesterone and estrogen, moreover, many other factors, such as growth factors, cytokines, ecm, adhension molecules, oligosaccharides and proteases, regarded as local mediators, endometrium and embryo have also expressed some specific receptors, via intracellular signal transduction chains and express some key genes, making receptivity of the uterus and synchronized development of the embryo to the blastocyst stage
成功的植入是處于接受態的子宮內膜和具有侵入性的胚胎間的同步協調反應。植入過程受多種生長因子及其受體、細胞因子、粘附分子、蛋白水解酶、寡糖等的精細調控,通過胞內信號轉導及關鍵基因的表達使子宮內膜發生一系列復雜變化。The cyst cells enclosing spermatomeres maybe synthesize a kind of scf - like protein, which can recognize specially the c - kit receptor on the cellular membrane of spermatomeres. then c - kit is activated, dimerizing and autophosphorylating. at the same time, the tyrosine kinase domain of c - kit is activized, which phosphorylates the proteins that have sh2 domain
精母細胞周圍的囊細胞可能合成scf樣蛋白,特異地識別精母細胞膜上的c - kit受體,並刺激c - kit發生二聚化、自體磷酸化,激活胞內酪氨酸激酶活性,活化具有「 sh _ 2結構域」的靶蛋白,可能通過一系列信號級聯,最終激活與減數分裂的相關蛋白或基因。Conclusion : folate - bsanp could be delivered into tumor cells via folate receptor - mediated endocytosis and significantly targeted to tumor cells with rich folate receptors
結論葉酸偶聯白蛋白納米粒能通過細胞膜上的葉酸受體介導內吞入胞,可顯著靶向于葉酸受體豐富的腫瘤細胞。Subject covers all major areas of cellular and molecular neurobiology including excitable cells and membranes, ion channels and receptors, synaptic transmission, cell type determination, axon guidance and targeting, neuronal cell biology, synapse formation and plasticity
本學科涵蓋了細胞分子神經生物學的所有主要領域,包括興奮細胞和細胞膜、離子通道和受體、突觸傳遞、細胞類型決定、軸突導向和定位、神經元細胞生物學、突觸形成和可塑性。Disruption of lipid rafts and caveolae by depleting cellular cholesterol with cholesterol - binding reagent, - methylcyclodextrin or filipin, blocks the igf - 1 receptor signaling in 3t3 - l1 preadipocyte. both hormone induced adipocyte differentiation and mitotic clonal expansion are inhibited by lipid rafts and caveolae disruption. however, a nonspecific lipid binding reagent, xylazine, does not affect adipocyte differentiation or mitotic expansing
利用膽固醇結合試劑,如甲基環糊精和菲律賓菌素,減少細胞膽固醇的含量,破壞細胞膜上脂質筏/質膜微囊的結構,抑制了igf - 1受體信號誘導的3t3 - l1前脂肪細胞的分化以及克隆擴增。Cellular membrane is the possible action site for elf - emf, and the related studies confirmed that the receptors on cell membrane could be clustered by physical stress factor, and the receptors transduced the signal into cells via cellular signal pathway
細胞膜是電磁場信號的可能耦合位點,相關研究也證實了細胞膜受體在細胞轉導物理性應激因子中的作用。This hypothesis provide a new thinking on the action of steroid hormone on neurons, and is both a challenge and a supplement to the traditional genomic theory, which held that the action of steroid hormone is solely mediated by its intracellular cytosolic receptor within the cell nucleus
年代首次在國際上提出糖皮質激素作用於神經元的快速、非基因組機制或膜受體假說。這是對傳統崽體激素基因機制或細胞學說的挑戰與補充,受到國際學術界的高度評價,曾應邀在第Thus, we also investigated the effects of elf - mf exposure on clustering of egf, tnf receptors in cultured cells
因此本文又進一步探索了極低頻磁場對細胞膜受體聚簇的作用。Superposition of noise magnetic fields inhibits clustering of fibroblast membrane surface receptors induced by 50 hz magnetic fields in chinese hamster lungs
工頻磁場誘導肺成纖維細胞膜受體聚簇及噪聲磁場的干預作用Some trends in the studies of cellular inorganic chemistry have been described in this review, which mainly contains the aspects of effects of metal ions including calcium ions and lanthanide ions and activated small molecule on ion channels, receptor proteins in the membrane, intracellular receptor proteins and cellular function
摘要本文評述了當前細胞無機化學研究中的幾個方面,主要是包括鈣離子和稀土離子在內的金屬離子和活性小分子對細胞膜離子通道、膜受體蛋白、胞內受體蛋白以及對細胞功能的影響。Dr. gilbert eriani 法國 cnrs search for essential nucleotides of yeast trna ( arg ) by in vivo selection of lethal mutants ( 03. 12. 16
廖侃研究員本室細胞膜結構在細胞膜受體信號轉導中的作用。 ( 03 . 12 . 11 . )The notch receptor is a cell surface molecule conserved from worm through man, and involved in cell fate determination of various cell lineages in many tissues throughout development
Notch是一種細胞膜受體, notch基因及其編碼產物的結構和功能從線蟲到人類幾乎所有生物中都是保守的,它們在發育中發揮著不可替代的作用。It is one kind is passed with distinctive, the cellular film that mixes high in person accepts put oneself in another ' s position union, adjust the polypeptide that the cell grows to wait for much effect with other cell function kind material
是一類通過與特異的、高親和的細胞膜受體結合、調節細胞生長與其他細胞功能等多效應的多肽類物質。分享友人