腫瘤結構基因 的英文怎麼說
中文拼音 [zhǒngliújiēgòujīyīn]
腫瘤結構基因
英文
neoplastic structural gene- 腫 : Ⅰ名詞(隆起處) swelling Ⅱ動詞(突起) swell; be swollen
- 瘤 : 名詞(瘤子) tumour
- 結 : 結動詞(長出果實或種子) bear (fruit); form (seed)
- 構 : Ⅰ動詞1 (構造; 組合) construct; form; compose 2 (結成) fabricate; make up 3 (建造; 架屋) bui...
- 因 : Ⅰ動詞[書面語] (沿襲) follow; carry on Ⅱ介詞1 [書面語] (憑借; 根據) on the basis of; in accord...
- 腫瘤 : tumour; core (綿羊體內的); neoplasm; phyma
- 結構 : 1 (各組成部分的搭配形式) structure; composition; construction; formation; constitution; fabric;...
-
This novel and efficient vaccine, with the non - cellular structure and no exogenous gene modification, is potential to be not toxic to the recipients. together with characters that it is easy to prepare, this non - cellular vaccine is promising in clinic
的確,由於exosomes具有非細胞結構、未經基因修飾和外源基因導入、對機體潛在危害作用小、制備簡單易行等優點受到大家的重視,成為研究新型腫瘤生物治療制劑和腫瘤疫苗的新方向。In order to further investigate the role of axudl in human tumor carcinogenesis and the potential association between the axudl gene expression status and the stimulation of transforming growth factor beta in human cancers, the present study was performed in three aspects as follows : ( 1 ) cloning full length enconding region cdna of axudl and construction of eukaryotic vector that expression the fusion protein of axud1 and influenza virus hemagglutin ha epitope tag ; ( 2 ) exploring the time and dose effects of tgf - 1 on the expression - of axudl gene in hepg2 hepatoma cells and spc - a1 lung carcinomas cells, and studying the effects of overexpression of axud1 on the expression of cell cycle and apoptosis related protein in hepg2 hepatoma cells ; ( 3 ) construction and expression of human axudl in e. coli m15. the following main results and conclusions can be obtained from the present study : 1. the full length ecnoding region of human axudl cdna from human peripheral blood lymphocytes was successfully cloned using one step rt - pcr method, and constructed into a eukaryotic expression vector which can be expressed a ha - axud1 fusion protein with axud1 and influenza virus hemagglutin ha epitope tag. the recombinant plasmid was identified by polymerase chain reaction, restriction endonuclease maping and sequencing, this expression vector might be instrumental to further study the function of axud1 protein in tumor cells
為了進一步研究axud1在人類腫瘤發生中的作用及axud1基因的表達狀況與tgf -介導的信號通路的關系,本實驗研究分為三個部分: ( 1 ) axud1基因cdna全長編碼區的克隆和ha表位標記的axud1基因表達載體的構建; ( 2 )探討肝癌細胞hepg2和肺腺癌spc - a1細胞中tgf - 1誘導的axud1基因表達的時間、劑量效應以及誘導表達的可能機理,並研究axud1的過表達對細胞周期和細胞凋亡相關蛋白表達的影響; ( 3 ) axud1原核表達載體的構建及其在大腸桿菌中的表達。本實驗的主要結果和結論如下: 1利用一步法rt - pcr成功地從人類外周血淋巴細胞中克隆出axud1基因編碼區cdna ,並將其構建入真核表達載體中,編碼的ha - axud1融合蛋白帶有流感病毒凝血素ha的表位標記肽段。Then using the technique of patent analysis and the following indicators such as patent numbers of past years, technology life circle, patent technology area, the competitive ability of facilities and so on. we analysed the patents in the area of gene therapy for cancers. swot method is also used to analyse the results from patent analysis, and then the developmental countermeasures are put forward
方法:通過對國內外生物制藥行業發展現狀的總體分析,及針對國內外腫瘤基因治療領域運用專利歷年數量、技術生命周期、地區分佈情況、專利技術內容、機構競爭力等專利分析指標與方法來進行對比分析,將分析結果結合運用swot分析法,提出相應發展對策。8kb cdna with 1362bp orf and codes 454 amino acids with only a sh2 domain. the gene was named as sh2a at chromosome 8p22. we study its structure by blast homologous analysis and its expression by rt - pcr and northern blot
本文將通過蛋白質分析軟體研究其結構和同源性,利用rt - pcr和northern印跡雜交技術研究該基因的表達情況及該基因與腫瘤的關系。分享友人