谷氨酸受體 的英文怎麼說
中文拼音 [gǔānsuānshòutǐ]
谷氨酸受體
英文
glutamate receptors, ionotropic-
Recently, ldl apheresis has been applied in clinic and achieves a satisactory effect. in this dissertation, the tripeptide, serine - aspartic - glutamic acid ( sde ), which existes in the cooh - terminal end of the seven repeats in the ligand binding domain of the ldl receptor and plays an important role in identifying ldl, was synthetized and immobilized onto the polyacrylamide ( paam ) beads as a bionic adsorbent for selective removal of ldl from plasma
本論文以絲氨酰-天冬氨酰-谷氨酸( sde )負電性三肽(此三肽廣泛存在於ldl受體配體結合域7個重復序列的羧基末端,對ldl受體特異性識別ldl起著重要作用)作為配體固定到聚丙烯酰胺微球載體上製成仿生性ldl親和吸附劑,考察其對人血漿中ldl及hdl的吸附功效。Regulation of excitatory amino acid release by n - methyl - d - aspartate receptors in rat hippocampus
天冬氨酸受體對清醒大鼠海馬谷氨酸釋放的調節作用It consists of fusiform neurons with intensely expressed neuropeptides in the fibers, terminals, and neuronal somata. functional connections between the mrd and hippocampus, amygdala and the basal nucleus of meynert were identified by c - fos expression method [ 14 ]
Nmdar在谷氨酸中樞神經系統的許多功能上具有關鍵作用, nmda受體激活后可引起神經元細胞膜對na + 、 k +和ca2 +通透性增強,產生興奮性突觸后電位。Its neuroprotective effect may be due, at least in part, to interact with presynaptic binding sites and inhibit glutamate and other transmitters release
因此, ginkgolideb的神經保護作用很可能或至少部分是由於它可以與突觸前膜的paf受體結合而抑制谷氨酸等神經遞質的釋放。Mechanism of glutamate - induced inhibition of pulmonary surfactant lipid synthesis ? mda receptor ( nmdar ) antagonist mk - 801 could reverse glutamate - induced inhibition of [ 3h ] - choline incorporation in lung explants ; ? he expression of nmdar1 subtype existed in alveolar type ii epithelial cells ; ? he effect of glu on pc synthesis required l - arginine in cultured lung explants, nos activity and no production were increased significantly in lung explants with glu treatment ; and mk - 801 and nos inhibitor l - nna could block the increase of nos activity and no production induced by glu ; l - nna also could reverse the inhibition of [ 3h ] - choline incorporation induced by glu ; ( 4 ) mda content increased and sod level decreased in cultured lung explants of glu treament groups, mk - 801 and l - nna could reverse these effects ; ( 3 ) mk - 801, l - nna could block the release of ldh induced by glu
谷氨酸對肺表面活性物質脂質合成抑制的機制研究nmda受體拮抗劑mk - 801能逆轉glu所致肺組織[ ~ 3h ] -膽堿摻入減少的效應;肺泡上皮細胞有nmda受體nmdar1亞單位的表達; glu對ps脂質合成的影響依賴l -精氨酸的存在, glu可使肺組織勻漿中nos活性、 no合成量升高; mk - 801 、 nos的抑制劑l - nna均可阻斷glu所致的這些效應; l - nna可逆轉glu所致肺組織[ ~ 3h ] -膽堿摻入減少的效應; glu可使肺組織勻漿中mda碩士學位論文中文摘要含量增高、 sod水平下降。 mk七0 、 l nna能阻斷q所致的這些效應; mk80 、 l nna還能阻斷gill誘導的ldh釋放增多的效應。The effects of metabotropic glutamate receptors in synaptic plasticity
代謝型谷氨酸受體在突觸可塑性中的作用研究進展Effect of the metabotropic glutamate receptor antagonist on diffuse brain injury through stereotactic injection into brain ventricle
立體定向腦室注射代謝性谷氨酸受體拮抗劑對彌漫性腦損傷影響的實驗His professional interests include the study of regulation of pulmonary surfactant synthesis, the function of clara cells, and the molecular mechanisms of acute lung injury
細胞抗肺纖維化及外周谷氨酸受體過度激活在急性肺損傷發生中作用的研究。Yu sp, yeh ch, strasser u, et al. nmda receptor mediated k + efflux and neuronal apoptosis j. science, 1999, 284 : 336
張錦華,張曉琴,章軍建.迷走神經刺激對戊四氮致癇大鼠丘腦網狀核谷氨酸受體的影響j .中國神經免疫學和神經病學雜志2002 , 9 ( 3 ) : 1252. formalin - induced nociceptive behavioral responses included two phases, and subcutaneous pretreatment of cpccoet or mpep significantly suppressed the tonic responses without effects on the acute nociceptive responses
第i組代謝型谷氨酸受體的拮抗劑cpccoet或mpe屍,可以明顯減弱福爾馬林注射引起的痛行為反應的第二相,而對第一相行為反應無明顯影響。A change in functional properties of the nmda receptors has been invoked as a potential mechanism contributing to the loss of synaptic plasticity during brain maturation. from this, it is important to well understand the structural and functional diversity of nmda receptors in relation to nmda receptor subunit composition and spatial distribution at excitatory synaptic sites during development
近幾年來,在哺乳動物中樞神經系統中,對離子型谷氨酸受體如何定位到興浙江大學醫學院碩士論文nrzb亞單位的c末端胞內區影響n協da受體裝配、運鈞以及表面表達的分子機制奮性突觸的研究有了長足的發展。Gene expression of neural related genes was identified by semi - quanti - tive rt - pcr analysis and genechip assay. 4 and 10 days after neural induction, gene expression pattern was analysed by genechips, which showed the expression of some neural stem cells and mature neurons specific and related genes, repectively. especially the expression of gabar and glutamate dehydrogenase ( gad ), which meant the induced cells could be gabanergic neurons
2 .基因晶元檢測到未分化escs 、神經幹細胞及成熟神經細胞的相關基因,並由半定量rt一pcr證實基因晶元檢測未分化細胞表達胚胎幹細胞特異基因;誘導后第4天細胞高表達神經幹細胞特異性基因;誘導后第10天細胞高表達成熟神經細胞特異性基因,且有gaba受體、谷氨酸脫梭酶( gad )表達,說明誘導后細胞大多為以ba能神經元。The mrd, firstly discovered by us with neuroanatomical and immunohistochemical methods, was a flat, pan - shaped structure at the caudomedial margin of the neostriatum and surrounding the rostrolateral edge of the globus pallidus in brains of the rat [ 12 ], cat [ 12 ], monkey [ 13 ] and human
研究的目的及意義:谷氨酸是哺乳類動物中樞神經系統的一種興奮性神經遞質,其受體分為離子型和代謝型兩類。離子型具有完整的陽離子通道,而代謝型( mglut )則通過蛋白轉到胞內信號系統而起作用。N - acetylcysteine is the acetylation of l - cysteine as the donor of sulfhydrylgruppe ( - sh ), not only has the great antioxidation, but also supplies the reduced glutathione in the body efficiently, and pretects the cell not to be injuried. the preventive effective of n - acetylcysteine against acute lung injury has been supported by the animal experiment and clinic research
N -乙酰半胱氨酸是l -半胱氨酸的乙酰化物,作為巰基的供體,不僅具有強大的抗氧化作用,還能有效補充機體內降低的還原型谷胱苷肽,保護細胞免受損傷,其對急性肺損傷的防治作用已獲得動物實驗和臨床研究結果的支持。分享友人