gene vaccine 中文意思是什麼

gene vaccine 解釋
基因疫苗
  • gene : n. 【生物學】基因。 dominant gene顯性基因。
  • vaccine : adj. 牛痘的；預防疫苗的；種痘的。n. 1. 疫苗，牛痘苗；菌苗。2. 【計算機】免疫程序軟體，抗病毒軟體。
  1. In recent years, the outbreak of nd appear some new characters, it is reported that the amount of immunity defeat on nd increased, even chicks with high hi titer can be infected by ndv virulent strain. the gene - engineering vaccine is badly needed to control nd outbreak. so newcastle disease virus strain b95, a naturally avirulent and heat stable strain, was introduced from australia

    新城疫是國際獸疫局公布的16種烈性傳染病之一。近年來，新城疫的爆發出現了許多新特點，免疫失敗報道增多，甚至抗體水平較高的雞群也發病。為控制新城疫的爆發，急需研製基因工程苗。
  2. Researches of schistosomiasis vaccines have gone more than 60 years, approximately including from the stages of dead vaccine and live vaccine ( irradiated attenuated cercariae vaccine ) to gene engineered vaccine, etc. many different forms of vaccines have been tested in animal models, including gluthathione s - transferase, paramyosin, irv - 5, triose phosphate isomerase, sm23, fatty acid binding protein ; which were considered promising by who / tdr. but none of them steadily accomplished the pre - set target level of 40 % protection. in order to enhance the protective capacity further, it is essential to develop novel vaccine antigens and / or vaccine adjuvants

    血吸蟲病疫苗研究已有60多年的歷史，大致經歷了死疫苗、活疫苗（照射致弱尾蚴疫苗）和基因工程疫苗等研究階段，產生了一些who / tdr推薦認為很有希望的疫苗候選分子，如谷胱甘肽- s -轉移酶（ gst ） 、副肌球蛋白（ sm97 ） 、照射致弱疫苗抗原5 （ irv - 5 ） 、磷酸丙糖異構酶（ tpi ） 、曼氏血吸蟲膜內在蛋白（ sm23 ）和脂肪酸結合蛋白（ fabp ， sm14 ）等，但其對宿主的保護作用均不甚理想，未能穩定地達到40或以上的保護力水平，因此有必要繼續尋找新的疫苗抗原分子和/或疫苗佐劑，進一步提高其保護力。
  3. Since the important roles of eo protein in the viral infection. immunity and virus - host interaction. the homology of 21 csfv strains was investigated by sequence analysis of eo genes in this study, which will provide some evidence for epidemiological study. in addition, the eo gene of hog cholera lapinized vaccine ( hclv ) strain was expressed in the prokaryotic and eucaryotic systems, and the recombinant proteins were preliminarily analyzed by immunological method

    鑒于eo蛋白在病毒感染，誘導機體免疫及與宿主細胞相互關系中的作用，本研究克隆了2株豬瘟病毒eo基因並將其與其它毒株eo基因進行了序列分析，揭示了我國豬瘟病毒流行株之間的遺傳演化關系，為豬瘟病毒的流行病學研究提供依據。
  4. There are many routes of dna vaccine immunization, including intramuscular injection, intradermal injection, subcutaneous injection, gene gun immunization, mucosa immunization, and so on

    核酸疫苗的接種有多種途徑，包括肌內、皮內、皮下注射途徑、基因槍免疫、黏膜免疫途徑等。
  5. In this study, the meaningful results have been achieved, which is the important basic work to research the pili subunit vaccine of avian e. coli, and detect pila gene by nucleric acid probe. moreover, it is significant to research molecular epidemiology, to diagnose, to prevent and treat avian colibacillosis

    本研究為雞源致病性大腸桿菌菌毛基因工程疫苗的研究，制備核酸探針檢測pila基因提供了重要材料，對雞大腸桿菌病的分子流行病學研究、診斷和防治研究具有重要意義。
  6. The purpose of this study was to clone the major structural protein vp3 gene of gpv hl isolate after pcr, and express by protokaryotic and eukaryotic expressing system, then develop molecuiar diagnostic reagent of goose piaque and construct recombillat fowlpox vina life vector vaccine

    利用pcr方法擴增和克隆gpvh1分離株主要免疫原性蛋白基因vp3 ，並對其進行原核和真核表達，是建立小鵝瘟分子診斷方法、構建vp3基因重組禽痘病毒活載體疫苗的基礎，具有極為重要理論和實踐意義。
  7. So gaining vp7 gene and its expressing product is key to the preparaion of the new type vaccine and specific diagnosis anigen

    因此，該基因的克隆及表達，對于制備新型疫苗和特異性診斷抗原具有重要意義。
  8. Sequence comparison indicated that the nucleotide homologies between the ha gene and those from eight other h3 subtype sfv isolates from china are over 95 %, and nucleotide identities between h3 sfv isolates in china and a typical h3 subtype avian influenza virus ( aiv ) strain dkuk1 - 63 are 95 % to 100 %. these might tell us that the ha gene of all h3 subtype sives isolated in china was originally from aiv although the vaccine based on ha do not protect against different subtype of influenza virus, it can provide favorable resistance to infection with antigenic variants within a subtype

    通過與其它7株國內siv分離株和6株genebank中的h3流感病毒ha序列比較分析，結果表明分離自我國不同地區的8株h3siv核苷酸序列同源性均在95 %以上，且與禽流感病毒（ aiv ）經典代表株dkuk - 63序列同源性在95 - 100 %之間，證實我國h3sivha基因來源於禽的流感病毒。
  9. This paper is a study on the expression of the protective gene of bont / a in the prokaryotic and eukaryotic. it indicates the possibility to produce the recombinant protein in quantities. it has also laid down a good foundation for the further research on vaccine or antibody of bont / a

    本論文進行了人工合成的a型肉毒毒素hc段基因在原核和真核表達系統中的表達研究，使制備大量bont a保護型抗原的重組蛋白成為可能，為進一步進行a型肉毒毒素的疫苗或抗體研究奠定了一定的基礎。
  10. Construction and identification of dna vaccine containing chimeric gene gag - gp120 of hiv

    120嵌合基因核酸疫苗的構建與鑒定
  11. Css is the one of the colonization factor antigens which is a protective antigen can cause immune reaction by the means taking orally. in this study, carrot was separately transformed with agrobacterium tumefacience strain lba4404 that contains ctb or ctb - cs3 fused gene in order to get oral diarrhea vaccine. this is a potent strategy to produce etec oral vaccine

    本研究期望通過農桿菌轉化系統將ctb （霍亂毒素b亞基，可作為佐劑和載體）基因和ctb - cs3融合基因分別轉入胡蘿卜植株，使ctb和ctb ? cs3融合基因穩定整合到胡蘿卜基因組內，希望以此獲得以胡蘿卜為受體的etec口服疫苗，使服食者在進食的同時就可獲得腹瀉免疫。
  12. Construction of recombinant fowlpox virus coexpressing aiv ha and ndv f. for the construction of transfer vector pfgs11haf, aiv ha gene of f strain in puc18ha and ndv f gene of f48e8 strain in puc19f were removed and inserted into pfgs11. recombinant fowlpox viruses ( rfpv ) coexpressing aiv ha gene and ndv f gene were constructed by using different promoters of ps and pe / l. recombinant rfpvs were derived by dosper liposome - mediated transfection with the two transfer vectors on chicken embryo fibroblast ( cef ) monolayer cultures which were infected by wild type fpv chinese vaccine strain 282e4 3 - 4 hours earlier

    Puc18ha和sk質粒同時經hind 、 kpn酶切后連接得中間質粒skha ；將質粒skha用bamhi酶切回收ha基因插入到插入載體pfgs11中的bamhi位點，通過酶切鑒定獲得了pfgs11ha ；將含ndvf基因的質粒puc19f用hind 、 sal酶切經klenow酶補平插入到經sma酶切后的skifn中pe / l啟動子下獲得中間質粒skf ，再將質粒skf和puc18質粒先分別用ecor 、 xho酶切klenow補平，后再共同用sac酶切連接得puc18pelf ， sal酶切回收pe / l - f基因盒插入到pfgs11ha的sal位點，通過酶切鑒定獲得了pe / l - f與ps - ha同向的表達載體pfgs11haf 。
  13. Living vaccine and killed vaccine have some formidable drawback, so biological technology vaccine, for example, gene vaccine and genetic engineering vaccine, is under the circumstances

    現在使用的弱毒苗和滅活苗都存在著一些難以克服的缺點，基因免疫和基因工程疫苗等生物技術疫苗的研製已勢在必行。
  14. The product cloned will provide reliable evidence for the establishment of quick and accurate molecular biological diagnostic method and lay a profound foundation for the stu dy of gene engineering vaccine of ai

    所克隆的基因為建立快速準確的分子生物學診斷方法提供了可靠的依據，同時為基因工程疫苗的研製奠定基礎。
  15. In this study, the recombinant fowl - poxvirus was transfected into expressing the vp3 gene of isolated gpv h1 strain into the cef cells with fpv - 017 by liposome, which have the lacz reporter gene, earlier / latter promoters lp2ep2 of fpv, promoters p7. 5 and p7. 1 of vaccinia virus, replication unnecessary region of fpv - 017. following 6 cycles screenings, clonings, purification of blue plaques, detection of pcr and dot - elisa, which verified the genetic stable vp3 - fowlpox virus recombinant constructed successfully. this study provided the theoretical and practical foundation for development of gpv recombinant fowl - poxvirus genetic engineering vaccine, as well as provided substance preparatory for prevention the high mortality gpv

    本研究採用脂質體轉染方法，將含有完整gpvh1分離株vp3基因、報告基因lacz 、禽痘病毒早晚期啟動子lp2ep2 、痘苗病毒啟動子p7 . 5 、 p11和fpv - 017復制非必須區的轉移載體質粒psy681vp3lacz與fpv - 017共轉染雞胚成纖維細胞，經6輪蝕斑克隆、篩選、表達， pcr鑒定和dot - elisa檢測，證明該重組病毒已構建成功，並獲得了遺傳性狀穩定的鵝細小病毒vp3基因的重組禽痘病毒。
  16. The result shows that a vvibdv strain was obtained, the above work lay a important role for further studying on the molecular biological mechanism of antigenic drift and virulence variation of ibdv, molecular epedimiology, it also provided the basis for recombinant and gene deleted vaccine of ibdv

    本實驗可以幫助我們進一步探討ibdv抗原性漂移和毒力變化的分子生物學機制，追溯ibdv的起源，理解病毒的傳播方式。同時也為研製開發基因重組疫苗和缺失疫苗打下一定的基礎。
  17. The plant gene vaccine series of products, jointly developed by the group and jianyang practical techniques research institute of china, have experimented through the broad farmland in china for three years running and won the approval of all farmer friends by its miraculous efficiency, safety, dependable and stable effect

    該集團與中國簡陽實用技術研究所合作開發的植物基因疫苗系列產品，在中國經過三年大田試驗，以其神奇的功效，安全、可靠、穩定的效果贏得農民朋友的認可
  18. Preparation of carcinoembryonic antigen positive tumor gene vaccine capsules for oral use

    癌胚抗原腫瘤基因疫苗膠囊的研製
  19. The result of this experiment provide an important basis for further study on gene vaccine and genetic engin eering vaccine of strain ha

    本研究結果為進一步研究mgh _ 3株的基因免疫和基因工程疫苗等奠定基礎。
  20. Construction of porcine reproductive and respiratory syndrome virus m protein gene vaccine and immunological experiment on mice

    蛋白基因疫苗的構建及在小鼠的免疫試驗
分享友人
分享到 Line

分享到臉書