Injected group, 0. 1 % saccharin ( 1. 5 ~ 2ml / rat, in 5min ) intraoral infused group and cta group. the expression of endogenous leucin - enkephalin ( lek ) in the rat brain was observed and 5 parts of the thalamus including laterodorsal thalamic nucleus ( ld ), lateral part of mediodorsal thalamic nucleus ( mdl ), ventroposterolateral thalamic nucleus ( vpl ), ventroposteromedial thalamic nucleus ( vpm ) and reticular thalamic nucleus ( rt ) were comparatively researched before and after the acquisition of cta applying lek - immunocytochemistry. in behavioral experiment, 18 adult male sd rats were divided into normal cta group ( control ) and 2 naloxone i. p
為探討cta形成過程中enk的作用,本實驗用成年雄性sd大鼠35隻,分為空白對照組、生理鹽水( 2體重)腹腔注射組、 0 . 15mlicl溶液( 2體重)腹腔注射組、 0 . 1糖精溶液口腔灌流組( 1 . 5 - 2ml只, 5min )和cta建立組,採用免疫細胞化學方法,觀察了亮腦
啡肽( lek )陽性神經元在大鼠腦內的分佈情況,並比較了各組大鼠丘腦外側背核( ld ) 、丘腦內側背核外側部( mdl ) 、丘腦腹后外側核( vpl ) 、丘腦腹后內側核( vpm )以及丘腦網狀核( rt )等5個腦區內lek表達水平的差異;另外將成年雄性sd大鼠18隻,分為正常cta建立組以及在cta建立前或cta建立后阿片受體拮抗劑納洛酮( 2mg kg體重)腹腔注射組,對內源性阿片樣物質對于cta建立和保持的影響進行了行為學研究。
Injections of α-endorphin acted as a tranquilizer and a mild analgesic.
注射內
啡肽後起鎮靜作用,也起和緩的止痛作用。
According to behavioral studies in adult rats, intrathecal administration of nociceptin, anandamide and win - 55, 212 ( win - 2 ) ( cannabinoid receptor agonists ) produces an antinoceptive effect in versatile pain models including acute, tonic and chronic pain models ( see mogil & pasternak, 2001 ; pertwee, 2001 for review ). thus, it could be concluded that nociceptin - orll receptor and anandamide - cannabinoid receptor systems constitute an important part of endogenous antinociceptive system. however, cellular mechanisms underlying the actions of orl1 and cannabinoid receptors on nociceptive information transmission in the spinal cord are still unknown
行為學研究也觀察到鞘內注入nociceptin和大麻受體的激動劑如win55 , 212 - 2 ( win - 2 ) 、 anandamide等均可在多種痛模型上(包括急性痛、持續性痛和慢性痛模型等)產生明顯的抗傷害性作用( seemogil pasternak , 2001 ; pertwee , 2001forreview ) ,由此可見nociceptin ?孤
啡肽受體系統和anandamide ?大麻受體系統構成了內源性鎮痛系統的重要組成部分。
Enkephalin ( enk ) is one of endogenous opiate like substance and could induce psychological euphoria and modulate function of learning and memory. however there has no report available about the role of enk in acquisition of sprague - dawley rats as materials
腦
啡肽( enk )是內源性阿片樣物質的一種,可參與情緒反應調節,引起精神欣快感,並對學習記憶具有調製作用。
Anti - beta - endorphin serum anti - dynorphin a1 - 13 serum
抗強
啡肽al - 13血清
There was much evidence showing that substantia gelatinosa ( sg ) of the spinal dorsal horn plays an important role in nociceptive information transmission from the periphery to central nervous system. thus, the present study firstly investigated the effect of nociceptin on membrane current of spinal dorsal hom substantia gelatinosa ( sg ) neurons by use of the whole - cell patch - clamp technique
故灘究首先應用脊髓薄片膜片鉗全細胞記錄技術觀察了在電壓鉗制下孤
啡肽受體的內源性配體nociceptin對脊髓背角sg神經元膜電流的影響作用以及其對脊髓背角興奮性和抑制性突觸傳遞的作用,其次觀察了nand
Changes in beta - endorphin immunoreactive positive neurons of hypothalamus arcuate nucleus and serum related hormone levels in ovariectomized rats
內
啡肽免疫反應陽性神經元數量及血清相關激素水平變化
" the finding was unexpected and is consistent with the hypothesis that frequent tanning may be driven in part by a mild dependence on opioids, most likely endorphins, " said steven feldman, a professor of dermatology at the university. " the nausea and jitteriness induced by the medication are consistent with symptoms of mild opiate withdrawal.
浸信醫學中心皮膚學教授斯蒂芬費德曼說: 「這個發現很令人意外,但剛好和之前的假設一致,那就是頻繁美黑也許是由於對如內
啡肽等類鴉片藥物的微弱依賴造成的,而那些藥物引起的惡心顫抖也與缺少鴉片的狀況一致。 」
Gamma oryzanol, comprised of sterols and ferulic acid esters, appears to increase testosterone levels and the release of endorphins, as well as the growth of lean muscle tissue
伽瑪-谷維素由甾醇酯和阿魏酸構成,可以提高睪丸素水平和促進釋放內
啡肽,還可促進精益肌肉組織的成長。
Watch at least one wholesome, funny show a week. laughing produces feel - good endorphins in your body that help ward off disease. and laughing keeps you optimistic
每一周至少觀看一場健康的、有趣的演出,歡笑會在你的體內產生出感覺良好的內
啡肽,這會幫助你抵禦疾病,而且歡笑還會讓你保持樂觀。
Methods the levels of orphanin fq in the plasma and the myocardial tissue of rat with internal capsule hemorrhage were determined by radioimmunoassay ( ria )
方法通過建立大鼠內囊出血模型,用放免法( ria )測定血漿及心肌組織勻漿中孤啡肽含量。