核苗酸 的英文怎麼說

中文拼音 [hémiáosuān]
核苗酸 英文
nucleotide
  • 核 : 核構詞成分。
  • 苗 : 名詞1 （初生的種子植物） seedling; sprout; shoots 2 （初生的飼養動物） the young of some animals ...
  • 酸 : 酸構詞成分。
  1. There are many routes of dna vaccine immunization, including intramuscular injection, intradermal injection, subcutaneous injection, gene gun immunization, mucosa immunization, and so on

    核酸疫苗的接種有多種途徑，包括肌內、皮內、皮下注射途徑、基因槍免疫、黏膜免疫途徑等。
  2. Many advantages and principles of nucleic acid vaccine were reviewed in detail. the progress of its application and studies on malaria, schistosomiasis, cysticercosis and leishmaniasis were mentioned briefly

    本文較為詳細地敘述了核酸疫苗的優點、作用機理，簡略介紹了核酸疫苗在瘧疾、血吸蟲病、囊蟲病和利什曼原蟲病的應用與研究進展。
  3. With the increase of concentration of aqueous extract from peganum multisectum increased, root vigor, the contents of chlorophyll, soluble protein and nucleic acid in roots and shoots of alfalfa seedlings decreased, while the activities of protease and nuclease, the contents of o2 ( superscript - ), h2o2 and malondiadehyde ( mda ) increased, the activities of superoxide dismutase ( sod ), catalase ( cat ) and peroxidase ( pod ) first increased and then decreased

    幼苗根系活力和葉綠素、可溶性蛋白質、核酸含量隨水浸液濃度的提高而降低，蛋白酶和核糖核酸酶活性及超氧陰離子（ o2 （上標- ） ） 、 h2o2和丙二醛（ mda ）含量則增加，超氧化物歧化酶（ sod ） 、過氧化氫酶（ cat ）和過氧化物酶（ pod ）活性呈先升后降變化。
  4. In this study, the meaningful results have been achieved, which is the important basic work to research the pili subunit vaccine of avian e. coli, and detect pila gene by nucleric acid probe. moreover, it is significant to research molecular epidemiology, to diagnose, to prevent and treat avian colibacillosis

    本研究為雞源致病性大腸桿菌菌毛基因工程疫苗的研究，制備核酸探針檢測pila基因提供了重要材料，對雞大腸桿菌病的分子流行病學研究、診斷和防治研究具有重要意義。
  5. This modification includes : ( 1 ) selecting two important molecules as candidates, ( 2 ) choosing a promiscuous t - cell epitope, and two b - cell epitopes or conserved amino acid sequences from the two important molecules, ( 3 ) connecting them adequately through analysis by the molecule designing software. therefore, the synthetic new antigen may interfere with the process of fertilization by multiple ways and its contraceptive effects may be enhancing. based on the molecule designing methods, the b - lymphocyte cell epitope of sperm / testis specific protein sp17 and cyritestin which interfere with fertilization in mouse, as well as the promiscuous th cell epitope of the ribonuclease ( rnase ) in bovine were selected

    本研究以蛋白質分子設計的理論和方法研究避孕疫苗，將sp17和cyritestin關鍵表位和牛核糖核酸酶非選擇性th細胞表位合理組合，獲得新抗原- 35肽序列；並在合成、純化後分別與弗氏佐劑、免疫刺激復合物（ iscoms ）混合后免疫不同遺傳背景的雌性小鼠，觀察血清和生殖道內的特異性抗體滴度的動態變化、生育力的改變以及免疫后小鼠重要臟器的組織病理學改變：以及在ivf下，新抗原的特異性抗血清對精卵相互作用的影響及抗原在精子表面的特異性定位。
  6. Effect of exogenous spermine on proteinase and rnase in wheat seedling under water stress

    外源精胺對水分脅迫下小麥幼苗蛋白酶和核糖核酸酶活性的影響
  7. Rt - pcr was used to amplify the cdna of the genome. these cdna fragments were cloned into the plasmid pucm - t. the result indicated that the seguence of the genome was obtained. the genome of aev - nh937 composed of 7055 nucleotides, potentially encodes a polyprotein of 2134 amino acids. the genome of aev - nh937 has 94. 3 % nucleotides identity with the calnek vaccine strain of aev

    把它們分段克隆在pucm - t載體上，經序列分析，獲得了aev - nh937毒株的基因組全序列及推導的氨基酸序列，基因組全長為7055個核苷酸，與calnek疫苗株具有94 . 3的同源性，編碼一個含2134個氨基酸的多聚蛋白。
  8. Construction and identification of dna vaccine containing chimeric gene gag - gp120 of hiv

    120嵌合基因核酸疫苗的構建與鑒定
  9. Cell immune response induced by hepatitis b virus dna vaccine in mice

    乙肝病毒核酸疫苗誘導小鼠細胞免疫應答的研究
  10. Preliminary study of purification process for the production of tuberculosis dna vaccine

    結核病核酸疫苗純化過程的初步研究
  11. Construction of helicobacter pylori hpaa nucleic acid vaccine and detection of its immunogenicity

    核酸疫苗的構建及免疫原性檢測
  12. This paper summarizes the elements of the nucleic acid vaccine, the preparation, the method and mode of inoculability, the effect of immunity and the securiy of vaccine in fish

    就核酸疫苗的作用機理、魚用核酸疫苗的構建、接種的方法和途徑、免疫效果以及安全性問題的研究作了概括。
  13. All the result showed that ndv f48e9 strain has its own speciality compared with other five ndv strains, and there were many difference between velogenic strains and lentogenic strains. so the infectious cdna of rnesogenic strains and lentogenic strain was far from enough to understand the replication, pathogenicity of ndv and the interaction between ndv and host cells, and the infectious cdna of velogenic strains ( eg. f48e9 ) was required to explain the relationships between structure and function

    本研究成功地獲得了ndvf48e9 t因組的核昔酸序列，並構建了表達ndvf48e9基因組cdna的低拷貝表達載體休f48e9 ，為構建新城疫病毒強毒株f48e9株的感染性cdna奠定了物質基礎，進一步研究ndv的生物學特性、結構與功能的關系；進一步探討影響ndv毒力的因素、以及研製新型疫苗載體提供了可靠保證。
  14. Construction and identification of a recombinant attenuated salmonella typhimurium vaccine strain expressing helicobacter pylori hpaa gene

    亞單位的重組減毒鼠傷寒沙門菌核酸疫苗的構建
  15. This study provides the basis evidence for the research of nucleotide sequence evolution relationship between domestic and exterior countries. it also establishes foundation for further research about developing gpv molecular diagnostic reagent and genetic engineering vaccine

    本研究為了解國內外鵝細小病毒核苷酸序列演化上的關系，為開發研製新型分子診斷試劑和抗鵝細小病毒感染的基因工程疫苗提供了理論依據。
  16. Sequence analysis indicated that the opening reading frame of ns1 gene is 1056nt in length, encoding 352 amino acids, identical to the sequence of strain sa 14 - 14 - 2 deposited in genbank. ns1 gene in the pmd18 - t - ns1 was cut by bamhi and hindiii, was cloned into the expression plasmid pet - 30b ( + ) treated with the same enzymes, resulting in a recombinant plasmid pet - 30b - ns1. the pet - 30b - ns1 was identified by pcr, restriction digestion, and sequencing

    通過序列分析結果表明， jev - ns1基因編碼區核苷酸序列長度為1056bp ，編碼352個氨基酸，序列分析和比較表明本實驗克隆到的ns1蛋白基因與genbank中收錄的疫苗株sa14 - 14 - 2的核苷酸序列一致，表明盡管該疫苗株在我國應用多年，但ns1基因並未發生變異，提示該疫苗株遺傳性狀比較穩定，是一株優良的疫苗株。
  17. The comparison of meq gene sequences of different pathotypes of marek ' s disease virus meq genes of different pathotypes of marek ' s disease virus ( mdv ) were amplified, in the whole opening reading frame ( orf ) by polymerase chain reaction ( pcr ) technique, sequenced and compared with the published sequence of ga strain ( representing vmdv ). cvi988 / rispens and 814, commercial vaccine strains popularly used worldwide and in china respectively ; 648a, representing very virulent plus ( vv + mdv ) and 6 field isolates, originated from guangxi commercial chickens with visceral lymphomas and vaccine breaks, representing high pathogenic ( hpmdv ) and two of them ( g2 and n ) were proved to be vvmdv, were used

    本研究通過三個方面進行了研究，取得了如下主要實驗結果： 1mdv不同致病型（ pathotypes ）毒株meq基因序列的比較研究應用pcr技術擴增了不同致病型mdvs ，即國際通用型疫苗毒cv1988 rispens株和中國特有的疫苗毒814株、特超強毒648a株（ vv + mdv ）以及6個廣西分離到的野毒株共9個毒株的meq基因，進行核苷酸序列的測定並與標準強毒ga株（ vmdv ）進行核苷酸和氨基酸序列的比較。
  18. The comparative analysis of sequences indicated that the sequences of meq in different pathotypes are relatively conserved and the homology of the amino acid sequences is very high. the significant differences include two mutations in both mdv - 1 vaccine strains cvi988 / rispens and 814 strain : the deletion of a proline ( no. l93aa ), and this mutation is just exactly located in a 15 - amino - acid ( eelcaqlcstppppi ) repeat sequence within the c - terminal transactivation domain of meq protein ; and a point mutation with a shift from alanine ( a ) of all virulent strains to serine ( s ) was occurred on the no. 71 aa

    結果發現， mdv不同致病型的meq基因序列相對比較保守，它們相互間核苷酸和氨基酸序列的同源性均很高；但是，與所有七個致瘤性的mdv毒株相比，二個型弱毒疫苗cv1988 rispens株和814株均出現了兩個特徵性的突變：即第194位的p缺失性突變和第71位氨基酸由a變成了s的位點突變；缺失性突變恰恰位於meq基因中轉錄激活域內的一個多脯氨酸的重復序列（ pppp ）之中。
  19. After transfection, we also testified the co - expression of pp38 and pp24 by ifa and by western - blotting with anti - gst - pp24 sera. we cloned and sequenced the pp38 and pp24 gene amplified from 814, cvi988 ( mmdv ), ga ( vmdv ), md5 ( vvmdv ), md11 ( vvmdv ), rblb ( vvmdv ), 648a ( vv + mdv ), and other 7 isolated strains from china. sequence analysis shows pp24 and pp38 gene are very conservative

    對包括型mdv疫苗毒、強毒、超強毒、特超強毒共7個國際參考株與7個中國分離野毒株的pp24基因和pp38基因分別進行了克隆測序，序列分析結果表明，型mdv的pp24基因和pp38基因均非常保守，比較的15個毒株的pp24基因的核苷酸和氨基酸之間的同源性分別高於98 . 9和98 . 1 ，同時比較的14個毒株的pp38基因的核苷酸和氨基酸之間的同源性分別高於99 . 4和99 . 0 。
  20. To explore the feasibility of ib edible vaccine, we have transformed si gene of ibv into potato and researched the immunogenicity of it ' s expression product. the findings are as follows : 1. a pair of primers for ibv si gene were designed and synthesized according to the published nucleotide sequence of ibv si gene and multiclone sites of expression vector pbi121

    為了探索ibv可食性疫苗的可行性，我們進行了轉基因馬鈴薯表達ibv免疫原基因及其表達產物免疫原性的研究，取得以下結果： 1根據周繼勇等報道的ibv - zj971毒株s1基因核苷酸序列和pbi121植物表達載體的多克隆位點，設計併合成引物，以含s1pbs質粒為模板擴增s1基因，將擴增片段定向克隆到pbi121質粒的35s啟動子下游。
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