核苷類似物 的英文怎麼說
中文拼音 [hélèisìwù]
核苷類似物
英文
nucleoside analogues-
Fatal lactic acidosis has been reported to patients who received didanosine and other antiretroviral agents
有報道同時應用核苷類似物的患者可能發生乳酸酸中毒，有時是致命的。The first drug approved for use against hiv, zidovudine ( azt ), is a nucleoside analogue as well
第一個上市對抗hiv的藥物是疊氮胸苷（ azt ） ，也是核苷的類似物。Mechanism of action : stavudine, a nucleoside analogue of thymidine, inhibits the replication of hiv in human cells in vitro
司他夫定是胸苷核苷類似物，可抑制hiv病毒在人體細胞內的復制。《 international hepatis 》 ： regarding to nucleoside analogs with hepatitis b antiviral treatment, the drug - resistance raised genetic barriers they, how do you understand genetic resistance barrier ? do you agree
《國際肝病》 ：關于抗乙肝病毒治療的核苷類似物，藥物耐藥性導致基因屏障概念的提出，你如何理解基因耐藥性屏障？你同意這種說法嗎？Research interests : organic synthesis, including synthetic methodology, divergent oriented organic synthesis, asymmetric synthesis, asymmetric synthesis of small molecules with biological significance ( alkaloids, amino acids, pheromones, nucleosides analogues, enzyme inhibitors, receptor agonists and antagonists, bioactive heterocycles etc ) and chiral drugs
研究興趣：主要從事有機合成化學及相關的化學生物學研究，包括合成方法學、多樣性導向有機合成、不對稱合成、有機小分子調節劑（生物堿，氨基酸，昆蟲信息素，酶抑制劑，受體拮抗劑，核苷類似物等）和手性藥物的不對稱合成。When treatment is deemed necessary the second difficult issue is whether to use interferon or analogues
治療時必需面對的第二個棘手的問題是是否使用干擾素或核苷類似物。Its km for sacilin at50 andph5. owas3. 73mg / ml. with the analysis of kinetics, the p - glucosidase showed synergistic action to the endoglucanase and the endoglucanase inhibited the p - glucosidase. the mechanism for their interaction was explained that the endoglucanase was combined with its products and the inhibition of these products to endoglucanase was removed by its hydrolysis by p - glucosidase
經兩組分共同作用的酶反應動力學分析后發現，兩組分這種相互作用機制的核心是：內切酶和?葡萄糖苷酶與內切酶的水解產物，也是其底物類似物? ?纖維二糖和纖維寡糖的結合以及-葡萄糖苷酶對該產物的水解。This article reviews the latest progress of nucleoside analogues on the treatment of multiple myeloma in recent years and introduces the mechanism of action, preclinical study and clinical application of fludarabine and gemcitabine in treating multiple myeloma
綜述了近年來核苷類似物治療多發性骨髓瘤的最新研究進展，介紹核苷類似物氟達拉濱和吉西他濱治療多發性骨髓瘤的作用機制、基礎研究和臨床應用。We have to admit however that, at least in the west, this patient profile is rarely encountered and most physicians would favour long - term treatment with analogues
我們不得不承認，至少在西方，大部分醫師選擇有利於長期治療的核苷類類似物。My first question is if hbv nucleoside analogues happened with the resistance there, then the solution is to add - on other nucleoside drugs for combination therapy, or switch another nucleoside drugs
《國際肝病》 ：乙肝用核苷類似物出現耐藥后，是加用其他核苷類藥物，還是轉換另外一種核苷類藥物？Because we know that treatment for hbv with analogues would be a very long term therapy, so their pre - resistance will be a very important one
因為我們知道慢乙肝用核苷類似物進行治療是一個長期的過程，所以基線耐藥是很重要的考慮因素。Viral dynamic studies showed more rapid decline of serum hbv - dna and eventually viral eradication in combination therapy of two different nucleoside analogues
病毒動力學研究表明：通過兩種不同的核苷類似物聯合治療，血清中的hbv - dna含量會快速下降，最終徹底消除。Background : in chronic hepatitis b, long - term use of alpha interferon is hampered by side effects, and long - term treatment with nucleos ( t ) ide analogues is burdened by drug - resistant mutants
背景：慢性乙型肝炎治療，長期使用-干擾素有副作用，而使用核苷類似物進行長期治療容易出現抗藥性突變體。Q : my first question is if hbv nucleoside analogues happened with the resistance there, then the solution is to add - on other nucleoside drugs for combination therapy, or switch another nucleoside drugs
《國際肝病》 ：乙肝用核苷類似物出現耐藥后，是加用其他核苷類藥物，還是轉換另外一種核苷類藥物？《 hepatology digest 》 ： now the interferon therapy is definite therapy, do you think our patients with chronic hepatitis b must accept the peginterferon therapy before they accept the nucleotides analogues treatment
《國際肝病》 ：目前干擾素治療慢乙肝具有肯定的療效，你認為慢性乙型肝炎患者在接受核苷類似物之前是否必須接受長效干擾素治療？Prognosis of chronic hepatitis b has been improved significantly because of the clinical application of nucleoside / nucleotide analogues, such as lamivudine, adefovir dipivoxil, entecavir
拉米夫定、阿德福韋酯和恩替卡韋等核苷/核苷酸類似物的臨床應用，大大改善了慢性乙型肝炎的預后。分享友人