生殖細胞定子 的英文怎麼說
中文拼音 [shēngzhíxìbāodìngzi]
生殖細胞定子
英文
germ cell determinant- 生 : Ⅰ動詞1 (生育; 生殖) give birth to; bear 2 (出生) be born 3 (生長) grow 4 (生存; 活) live;...
- 殖 : 殖Ⅰ動詞(生息; 孳生) breed; grow; multiply Ⅱ名詞(姓氏) a surname
- 細 : 形容詞1 (條狀物橫剖面小) thin; slender 2 (顆粒小) in small particles; fine 3 (音量小) thin ...
- 胞 : Ⅰ名詞1 (胞衣) afterbirth2 (同一個國家或民族的人) fellow countryman; compatriot Ⅱ形容詞(同胞...
- 定 : Ⅰ形容詞1 (平靜; 穩定) calm; stable 2 (已經確定的; 不改變的) fixed; settled; established Ⅱ動詞...
- 子 : 子Ⅰ名詞1 (兒子) son 2 (人的通稱) person 3 (古代特指有學問的男人) ancient title of respect f...
- 生殖 : reproduction; engender
- 細胞 : cell; sytes; bioplast; cella; [口語] gene; [生物學] cellule; cellule cellulli cellulo ; cello ; k...
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This modification includes : ( 1 ) selecting two important molecules as candidates, ( 2 ) choosing a promiscuous t - cell epitope, and two b - cell epitopes or conserved amino acid sequences from the two important molecules, ( 3 ) connecting them adequately through analysis by the molecule designing software. therefore, the synthetic new antigen may interfere with the process of fertilization by multiple ways and its contraceptive effects may be enhancing. based on the molecule designing methods, the b - lymphocyte cell epitope of sperm / testis specific protein sp17 and cyritestin which interfere with fertilization in mouse, as well as the promiscuous th cell epitope of the ribonuclease ( rnase ) in bovine were selected
本研究以蛋白質分子設計的理論和方法研究避孕疫苗,將sp17和cyritestin關鍵表位和牛核糖核酸酶非選擇性th細胞表位合理組合,獲得新抗原- 35肽序列;並在合成、純化後分別與弗氏佐劑、免疫刺激復合物( iscoms )混合后免疫不同遺傳背景的雌性小鼠,觀察血清和生殖道內的特異性抗體滴度的動態變化、生育力的改變以及免疫后小鼠重要臟器的組織病理學改變:以及在ivf下,新抗原的特異性抗血清對精卵相互作用的影響及抗原在精子表面的特異性定位。Biological activity was determined by egf dependent balb / c 3t3 cell line and with mtt colorimetric assay. extracts of the recombinant virus - infected and mock - infected cells, haemolymph of the recombinant virus infected and mock - infected silkworm larvae could all support the proliferation of balb / c 3t3 cell. this phenomena implied that there were some egf - like growth factors in the haemolymph of normal silkworm larvae, which could enhance the proliferation of the cell line
用小鼠balb c3t3成纖維細胞和mtt法測定表達產物的促細胞增殖作用,發現重組病毒感染家蠶細胞72小時的胞內樣品與正常家蠶細胞裂解物,以及重組病毒感染4天的蠶血淋巴與正常蠶血淋巴均具有相似的促細胞增殖作用,甚至野生型病毒感染的細胞裂解物和蠶血淋巴也有一定的細胞促生長作用,提示家蠶系統本身可能含有能促進細胞生長、類似於egf的細胞因子。In young chickens aev induces paralysis, ataxia and muscular dystrophy, while in older chickens, infection is usually subclinical, resulting in a decline in egg production and hatchability. infectivity was shown to remain unaffected by chloroform, low ph, pepsin, trypsin and deoxyribonuclease. magnesium cations were shown to stabilise preparations of the virus against heat inactivation. the buoyant density of virions are 1. 31g / ml. the diameter of the virion was estimated to be 22 to 30nm. the aev can be adapted to grow in chicken embryo. the inability of aev to grow effeciently in most cell cultures
幼雞感染該病毒后,引起麻痹、頭頸震顫甚至共濟失調,而成雞常呈亞臨床感染或導致產蛋量和孵化率下降。病毒的感染性不受氯仿、低ph 、胃蛋白酶、胰酶和脫氧核糖核酸酶的影響,鎂離子可增強病毒對熱的穩定性,病毒的浮密度為1 . 31g ml ,直徑為22 - 30nm ,該病毒主要在雞胚中增殖,在大多數細胞培養物中不生長。Cell adhesion to surface of the substrate is essential to development of the anchorage - dependent cells. only after adhering to surface followed by spreading can cells develop and proliferate. most synthetic polymers used as orthopaedic matrix substitute present hydrophobicity, which may correlates to the low degree of cell attachment. modification with cell adhesion protein / peptides can be benificial to the cell adhesion on polymers and then affect the cell proliferation and differentiation. cell attachment to substrate is primarily mediated by integrins, a widely expressed family of heterodimeric surface receptors. most extrcellular matrix proteins such as fibronectin, osteopontin, collagen type i, bone sialoprotein and vitronectin contain an arg - gly - asp ( rgd ) sequence which is specific to the fixation of cell membrane receptors like integrin. the main aim of this research is to measure, assess adhesion, proliferation of rabbit marrow stromal cells ( mscs ) on the polymers coated by fibronectin, collagen type i or biotie gen, which includes : ( 1 ) biologic characteristics of rabbit mscs were observed by two types of separating method in primary culture. ( 2 ) adhesion, proliferation and differentiation of mscs cultured on polymers coated with biotiegen were assessed. ( 3 ) also, adhesion, proliferation and differentiation of mscs were assessed on plga film or porous plga substrates coated with fibronectin, or collagen type i respectively. ( 4 ) bone formation was observed on the porous plga substrates coated with collagen type i in vivo. this research aims to give new way to make novel synthetic bone with cell adhesion and high bone induction capabilities
因此將這些蛋白包被、固定到材料表面,觀察骨組織工程種子細胞mscs細胞的粘附、生長特性是本研究的中心環節,並從以下方面進行探討: ( 1 )採用不同原代細胞分離方法,研究其對mscs細胞的生物學特性影響。 ( 2 )檢測基因勝肽膠對mscs細胞粘附、增殖及分化的影響。 ( 3 )分別採用型膠原及纖維粘連蛋白( fibronectin , fn )包被聚乙醇酸-乳酸共聚物( poly ( 1actide - co - glycolide ) , plga )膜及多孔塊型plga材料,觀察細胞在單層或三維培養狀態下,型膠原及fn對mscs細胞粘附、增殖及向成骨細胞分化效應及能力。Objective platelet - derived growth factor ( pdgf ) and thyroid hormone ( t _ 3 ) have important effects on regulating the proliferation and destined differation of the neural stem cell ( nsc ). there is an interaction between them. the thyroid hormone receptors ( thr ) is the hinge of the interaction
目的:甲狀腺激素( t _ 3 ) 、血小板衍生生長因子( pdgf )在調控神經幹細胞( nsc )的增殖與定向分化方面有著很重要的作用,它們之間存在著交互作用,甲狀腺激素受體( thr )則可能是這種交互作用的樞紐,兩者通過thr各亞型共同調控著cns的正常發育。分享友人