癌抑制基因 的英文怎麼說
中文拼音 [áiyìzhìjīyīn]
癌抑制基因
英文
suppressor oncogene- 癌 : 名詞[醫學] (惡性腫瘤) cancer; carcinoma
- 抑 : Ⅰ動詞(向下按; 壓制) restrain; repress; curb Ⅱ連詞[書面語]1 (表示抉擇) or 2 (表示轉折) but3 ...
- 制 : Ⅰ動詞1 (製造) make; manufacture 2 (擬訂; 規定) draw up; establish 3 (用強力約束; 限定; 管束...
- 因 : Ⅰ動詞[書面語] (沿襲) follow; carry on Ⅱ介詞1 [書面語] (憑借; 根據) on the basis of; in accord...
- 抑制 : 1 (控制) restrain; control; check; hold up; curb; stop; repress; bridle; choke; prehension; sup...
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In 2005, researchers at sloan - kettering reported that the gene could stop massie tumor growth in prostate cancer een when another tumor suppressor, known as p53, was turned off
早在2005年,斯隆-凱特琳中心的研究人員就曾報道了在另一種叫做p53的腫瘤抑制基因關閉時,該基因甚至仍然可以阻止前列腺癌大腫瘤生長。Curcumin has been shown to induce a wide variety of tumor cells by several mechanisms, mainly including modulation of the expression of oncogenes and cancer suppressor genes, down - regulation the activation of transcription factors, via many signal transduction pathways, and the modulation of cell cycle. provides an overview of domestic and international apoptosis mechanisms of malign tumor cells induced by curcumin in order to better explore and open up new avenues of cancer treatment
姜黃素能夠誘導多種腫瘤細胞系凋亡,其機制主要是調控癌基因和抑癌基因,下調多個轉錄因子活性,通過多種信號轉導途徑,誘發細胞周期停滯而誘導細胞凋亡.對近年來姜黃素誘導細胞凋亡的機制進行綜述,以便更好地探求和開辟治療惡性腫瘤的新途徑。Since evidence shows anti - estrogen drugs will fail in a many patients with estrogen - receptor - positive breast cancer, says knudsen, our research suggests that physicians should examine both estrogen receptor status and rb tumor suppressor status during the initial diagnosis, in order to prescribe the most effective therapy for that specific patient ' s cancer.
證據表明,抗雌激素藥物對雌激素受體陽性乳癌將失效,我們的研究提示,為了給那些特殊癌癥患者制定最有效的治療方法,醫生應該在開始診斷時檢測雌激素受體和rb抑癌基因狀況。Since eidence shows anti - estrogen drugs will fail in a many patients with estrogen - receptor - positie breast cancer, says knudsen, our research suggests that physicians should examine both estrogen receptor status and rb tumor suppressor status during the initial diagnosis, in order to prescribe the most effectie therapy for that specific patient ' s cancer.
證據表明,抗雌激素* *物對雌激素受體陽性乳癌將失效,我們的研究提示,為了給那些特殊癌癥患者制定最有效的治療方法,醫生應該在開始診斷時檢測雌激素受體和rb抑癌基因狀況。Germline mutations in the brca1 or brca2 tumour - suppressor genes are strong predictors of breast and / or ovarian cancer development
在brca1或brca2腫瘤抑制基因的種系突變是乳腺癌和/或卵巢癌進展的強烈預測指標。Neoplasia, or uncontrolled cellular proliferation, can result either from mutations that " turn on " the oncogenes that stimulate growth, or from mutations that result in loss of tumor suppressor genes and their products that inhibit growth
腫瘤或失去控制的細胞增生是由於突變使癌基因啟動從而促使增生,或者由於腫瘤抑制基因和腫瘤抑制基因產物的缺失。For example, as a direct toxic effect, periodontal iruses and bacteria and their products ( endotoxins or enzymes, for example ) are toxic to surrounding cells and may directly induce mutations in tumor suppressor genes and proto - oncogenes or alter signaling pathways that affect cell proliferation or surial of epithelial cells
例如,作為直接毒性作用,牙周病毒和細菌及在細胞周圍其產生的毒性物質(例如,類毒素或酶類)可直接誘導腫瘤抑制基因和原癌基因突變或者改變細胞信號傳導通路從而影響上皮細胞增殖或存活。For example, as a direct toxic effect, periodontal viruses and bacteria and their products ( endotoxins or enzymes, for example ) are toxic to surrounding cells and may directly induce mutations in tumor suppressor genes and proto - oncogenes or alter signaling pathways that affect cell proliferation or survival of epithelial cells
例如,作為直接毒性作用,牙周病毒和細菌及在細胞周圍其產生的毒性物質(例如,類毒素或酶類)可直接誘導腫瘤抑制基因和原癌基因突變或者改變細胞信號傳導通路從而影響上皮細胞增殖或存活。This silencing also affects the function of many tumor suppressor genes, which, in their unmethylated state, put the brakes on uncontrolled cell growth
這種沉默也影響許多抑癌基因的功能,這些基因在非甲基化狀態下可以阻止不受控制的細胞生長。Doc - 1r gene is an candidate tumor suppressor gene which was discovered by zhangxue. it can interact with cdk2 specifically and restrain cdk2 transportation into the nucleus, which will block the formation of cdk2 and cyclin complex and hinder the process of cell cycle
Doc - 1r基因是張學等發現的一個候選抑癌基因,它可與cdk2特異性結合,抑制cdk2的入核轉運,使cdk2不能與cyclin形成復合物,從而阻抑細胞周期的進程。Many cancers arise due to defects in genes that normally suppress tumor growth
眾多癌癥的發生是因抑制腫瘤生長的基因缺乏。Dong z, bonfil rd, chinni s, et al. matrix metglloproteinase activity and osteoclasts in experimental prostate cancer bone metastasis tissue [ j ]. am j pathol, 2005, 166 ( 4 ) : 1173
王醫術,周洪瀾,李亞娟,等.基質金屬蛋白酶及其抑制因子在前列腺癌侵襲和轉移中的作用[ j ] .吉林大學學報, 2006 , 32 ( 5 ) : 847Experimental study on silencing bcl - 2 expression by inducible sirna inhibits gastric cancer cells
2基因抑制胃癌細胞生長的研究Svde gene was also amplified from spinach by rt - pcr. the plant expression vector pcb - antisvde was constructed, in which svde gene was controlled by camv35s promoter and nos terminator. antisense transgenic tobacco plants v. ere obtained from leave explants via agrobacterium tumefaciens - medialed transformation
從菠菜中克隆了svde基因,並構建了該基因的反義抑制植物表達載體pcb - antisvde ,用根癌農桿菌介導法轉化煙草,獲得了大量的轉基因植株。Recombinant adenovirus vectors carrying antisense matrix metalloproteinase - 2 inhibits hepatocellular carcinoma growth in vivo
2基因抑制肝癌生長的實驗研究分享友人