血型嵌合體 的英文怎麼說
中文拼音 [xiěxíngqiàngětǐ]
血型嵌合體
英文
blood group chimera-
Part 1 : the culture and identification of es - d3 cells and the study of the efficiency of eb formation from es cells when grown on mef feeder layer in es culture medium or cultured in es culture medium supplemented with lif 1000u / ml, es - d3 cells being used in our experiments formed normal clones, expressed akp and kept their normal karyotype over many passages. the in vitro and in vivo differentiation experiments showed that es - d3 cells could differentiate into variety of cell types derived from three primary germ layers
結果顯示: eso3細胞在小鼠胚胎成纖維細胞上和或含白血病抑制因於億f )的es細胞培養液中形成典型的胚胎幹細胞克隆,堿性磷酸酶染色結果為強陽性,具有正常二倍體核型以及具有在體內外分化為三個胚層來源的組織細胞的潛能,而且具有形成種系嵌合動物的能力。In contrast to murine studies, studies of human hscs have relied on a number of in vitro assays that identify cells with the capacity to generate hematopoietic progenitors in long - term culture and to differentiation into multiple hematopoietic lineages. recently, two elegant animal models that enable the in vivo measurement of human hscs marrow repopulating potential have been developed. one is the sheep in utero transplantation system in which human hematopoietic progenitor cells are transferred into the sheep fetus in utero before the development of the ovine immune system
早在80年代中期, zanjani等就利用胚胎期免疫系統發育不完善,將人的造血幹細胞移植到妊娠中期胚羊腹腔內,成功地建立了人胎羊造血幹細胞嵌合體移植模型,並以此實驗模型作為體內檢測人造血幹細胞和人骨髓間充質幹細胞多向分化潛能的方法。
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