誘變物質 的英文怎麼說
中文拼音 [yòubiànwùzhí]
誘變物質
英文
mutagen matter-
Diet acrimony, sootiness, salt bloats, mildew changes, cankered food : hot food stimulates gastric mucous membrane, as time passes injures gastric mucous membrane ; carcinogenic substance of fumigated food generation can be caused and aggravating illness ; nitric acid salt is contained in souse food, very powerful carcinogen can be formed after with food medium nitrite is united in wedlock - - inferior saltpetre amine ; mildew changes element of very strong carcinogen yellow aspergillus is contained in food ; cankered material can produce effluvial carcinogen aldehyde. 2
忌食辛辣、煙熏、鹽腌、霉變、腐爛食品：辛辣食物刺激胃粘膜，久而久之損傷胃粘膜；熏制食物產生致癌物可誘發和加重病情；腌制食物中含有硝酸鹽，和食物中的亞硝酸鹽結合后可以形成很強的致癌物質? ?亞硝胺；霉變食物中含有很強的致癌物質黃麴黴素；腐爛的物質可以產生惡臭的致癌物質乙醛。Section two the evaluation of biocompatibility of the acellular dermal matrix by the method of cell culture. the new born rat ' s epdermic cells were cultured with the acellular dermal matrix together as experiment group, while the epdermic cell were cultured simply as control. 24 hours later, under the invert microscope, the epidermic cells anchored well and transparent flat cells were observed in both groups. 7 days later, both cultured cells were taked out and fixed in 95 % ethanol, stained with hematoxylin and were observed under light microscope. many cleaved cells were observed in both groups. during cell culture, no pathogenic microganism was observed. so we considered the acellular dermal matrix was aseptic and had good biocompatibility. section three subdermal implantation of the acellular dermal matrix. 24 rats were used in the experiments. a piece of acellular dermal matrix ( 1. 5 x 1. 5cm2 ) was implanted beneath the dorsum skin flaps of each rat, 1 week, 2 weeks, 3 weeks and 4 weeks after implantation, 6 pieces of acellular dermal matrix were harvested and the size of implanted acellular dermal matrix were measured, the sections were used for he staining and observed under light microscope. the result were as folio wing : 1 - 2 weeks after implantation, the acellular dermal matrix began to adhere to the tissue around and turned red gradually ; 3 - 4weeks after implantation, the acellular dermal matrix adhered closely to the tissue around and could be recognized easily, 1 - 3 weeks after implantation, the size of implanted acellular dermal matrix had no statistical difference ( p > 0. 05 ). 4 weeks after implantation implanted acellular dermal matrix contracted ( p < 0. 05 ). under light microscope, l - 2weeks after implantation, the fibroblast cells infiltrated the acellular dermal matrix and a small amount endothelial cells of vessel and lympho - histiocytic cells infiltrated the acellular dermal matrix. 3 - 4 weeks after implantation, infiltrating blood vessels were evident. so we think that the acellular dermal matrix had low immunological reactions and could induce the infiltration of fibroblast macrophage cell and the endothelial cells of vessel
結果如下：皮下包埋卜周者，無細胞真皮基質漸與周圍組織粘附，顏色由蒼白轉紅；皮下包埋3周者，無細胞真皮基質與周圍組織緊密枯附，盾晰葉辯；術后卜周，包埋的基質面積變化較包埋前無統計學差異o川0引，術后4周包埋的無細胞真皮基質面積較包埋前縮小j刃刀5 ） 。光鏡下術后卜周，宿主的淋巳組織細胞、成纖維細胞浸入生長，釉附在膠原纖維上，少量血管內皮細胞浸入基質；術后34周，無細胞真皮基質內較多的血管形成，故可認為無細胞真皮基質免疫原性低，能誘導宿主的成纖維細胞、巨噬細胞浸入生長，為一種新型的真皮替代物。第四部分無細胞真皮基質與自體斷層皮片復合移棺的研究， sd大鼠10隻，在其背部卜方造成全厚皮膚缺損的創面Monofunctional alkylating agent n - methyl - n ' - nitro - n - nitrosoguanidine ( mnng ) is a widely spread environmental mutagen and carcinogen that targets dna and proteins to generate adducts. among the adducts, o6 - alkyl guanine is the predominant mutagenic lesion because of its mispairing properties, which can eventually lead to chromosomal aberrations, point mutations, and cell death. this lesion also appears to be involved in tumor initiation, particularly in gastric carcinogenesis
單功能烷化劑n -甲基- n -硝基- n -亞硝基胍（ mnng ）是一種在環境中廣泛存在的化學誘變劑和致癌劑，它能和dna及蛋白質等生物大分子形成加合物（ adduct ） ，其引起的與突變有關的主要dna損傷類型是o ~ 6 -甲基鳥嘌呤，這種損傷與腫瘤尤其是胃癌的發生密切相關。Induction of metamorphosis of the southern bay scallop argopecten irradians concentricus larvae by chemical cues
化學物質對墨西哥灣扇貝幼蟲變態的誘導In our laboratory, a unique mutation detection system using a shuttle vector plasmid has been established to demonstrate that a low concentration of mnng ( 0. 2 m ) can induce nontargeted mutation in mammalian cells : the mammalian cells were exposed to 0. 2m mnng for 2. 5h, then a shuttle plasmid pz189 carrying supf trna gene was transfected into cells after 24h culture. we found a 5 - fold higher mutation frequency of the plasmid replicated in pretreated cells than the spontaneous mutation frequency of the plasmid replicated in control cells. this kind of mutation did not occur immediately after mnng exposure
我們實驗室曾用一特殊的突變檢測系統，直接證明dna損傷劑可在哺乳動物細胞誘發非定標性突變：首先用低濃度（ 0 . 2 m ）的短壽烷化劑mnng （半壽期為1 . 1hr ）處理細胞2 . 5h后，繼續培養24h ，將重組有用作突變檢測的靶基因supftrna基因的穿梭質粒pz189轉入細胞復制，發現在未受致癌物直接攻擊的穿梭質粒中有較自發突變率高5倍以上的靶基因突變。Lovrin 10 and cv. 5389. by using this system, following questions were investigated : the change of the pattern of microtubules when treated with iwf ; the change of cytosolic calcium levels in the protoplasts when treated with iwf and the influence of microtubule depolymerization prior to iwf treatment on the levels of cytosolic calcium
試驗的目的是以激發子?原生質體簡化試驗系統來模擬葉銹菌侵染小麥葉片的互作體系，探討激發子刺激后寄主植物微管骨架的動態變化及胞內ca ~ （ 2 + ）水平的變化規律，為進一步探討激發子誘導防衛反應的信號轉導途徑奠定基礎。One is about of temperature - dependence of luminescence of eu3 + and tb3 + doped in oxide glass and nanocrystalline y2o3 ; the other is about of light - induced luminescent and structural change in nanocrystalline y2o3 : tb. the creative works are as follows : ( 1 ) euand tb doped nanocrystalline y2o3 with different sizes were prepared by combustion synthesis. dependences of particle size, crystallinity and fluorescence characteristic on ratio of gly / y ( no3 ) 3 and annealing temperature were studied
本文以變溫與光輻照為實驗方法研究了eu與tb摻雜y _ 2o _ 3納米晶及氧化物玻璃中發光性質隨溫度的變化關系和光誘導y _ 2o _ 3 ： tb納米晶發光性質及結構的改變過程，得到如下創新性研究成果： （ 1 ）用燃燒法制備了稀土摻雜y _ 2o _ 3納米晶，研究了甘氨酸與硝酸釔的反應比例（ g n ） 、退火條件對稀土摻雜y _ 2o _ 3納米晶顆粒尺寸、結晶狀況及發光特性的影響。The emphasis of the paper is the influence of the shifts of metabolic process induced by environmental factors such as dissolved oxygen, temperature, aerial pre - exposure and pre - exposure to chemicals on the accumulation and transport of dissolved metals
綜述溶解氧、溫度、空氣預暴露、化學物質預暴露等環境因子，誘導的機體代謝過程的改變，對溶解態重金屬的累積和轉運過程的影響。The results were as follows : ( l ) the pre - incubation of pmr induced the exocytosis of the cortical granules ( cgs ) in the oocytes and reduced the quantity of the microvillus on the surface of oocytes ; ( 2 ) the matrix of cg might migrate to the surface of plasma membrane of oocytes after pmr pre - treatment. ( 3 ) incubation of zona - free hamster eggs with spermatozoa pretreated with pmr a ntiserum was associated with a dose - dependent significant reduction in the number of spermatozoa binding to the oolemma, compared with a contraband with a dose - dependent reduction of the fertilization rate and the penetration index. the results indicate that mr of human sperm plays an important role in sperm - oocyte fusion and oocyte activation
結果顯示： （ 1 ）人精子mr能夠誘發去透明帶金黃地鼠卵母細胞中皮質顆粒的胞吐，並引起卵母細胞膜表面微絨毛形態和數量發生改變； （ 2 ）皮質顆粒胞吐后，其內容物可結合到卵膜表面； （ 3 ）抗mr抗血清預處理精子可抑制精子與卵子的結合與融合，使受精率、穿透指數和結合指數下降，並均有劑量依賴性。以上結果提示，人精子mr在受精過程中起重要作用，其主要作用可能是介導精-卵膜融合併促進卵母細胞的活化。It distributes widely and survives easily. smears of blood samples were prepared conveniently ; and there is no restriction on seasons. for these reasons, mcn and ona test in erythrocytes of loach is rather useful index for detecting mutagenetic compounds in the aquatic environment
研究結果表明，泥鰍對于核變異的誘發具有較高的敏感性，且泥鰍分佈較廣，易存活，且血量也較搬料多，並能在不同季節評測水質狀況，因此，泥鰍紅細胞微核和核異常測試法可作為監測水環境中致變化合物的一個較為實用的指標。For example, as a direct toxic effect, periodontal iruses and bacteria and their products ( endotoxins or enzymes, for example ) are toxic to surrounding cells and may directly induce mutations in tumor suppressor genes and proto - oncogenes or alter signaling pathways that affect cell proliferation or surial of epithelial cells
例如，作為直接毒性作用，牙周病毒和細菌及在細胞周圍其產生的毒性物質（例如，類毒素或酶類）可直接誘導腫瘤抑制基因和原癌基因突變或者改變細胞信號傳導通路從而影響上皮細胞增殖或存活。For example, as a direct toxic effect, periodontal viruses and bacteria and their products ( endotoxins or enzymes, for example ) are toxic to surrounding cells and may directly induce mutations in tumor suppressor genes and proto - oncogenes or alter signaling pathways that affect cell proliferation or survival of epithelial cells
例如，作為直接毒性作用，牙周病毒和細菌及在細胞周圍其產生的毒性物質（例如，類毒素或酶類）可直接誘導腫瘤抑制基因和原癌基因突變或者改變細胞信號傳導通路從而影響上皮細胞增殖或存活。It has been proved that hereditary basis can be improved to create new varieties by different ways or methods such as introducing overseas germplasm resources to transduce into wild species, mutagenic breeding, space breeding, biotechnology breeding, etc., it is possible to improve mightily sugar beet breeding
實踐證明，通過引進國外種質資源並導入野生種質、誘變育種、航天育種、生物技術育種等途徑方法，能拓寬遺傳基礎，創造不同類型新品種，使甜菜育種工作上一新臺階。The results demonstrated that the expression of high - temperature resistance resulted in the marked changes both in ultrastructures of fungus and that of host mesophyll cells, forming infection - induced defense structure and materials
結果表明，高溫抗銹性的表達使病菌和寄主葉肉細胞超微結構都發生明顯的變化，形成了侵染誘導的防衛結構和物質。2 ) measured the survival curves for the cells overexpressing mutant alleles of gpil7p and chosed the proper cu2 + concentration in the medium for inducing
2 ）測定過表達了突變gpi17p細胞的存活曲線，並確定了培養介質中誘導物銅離子的適宜濃度。The transition matrix elements are obtained by analytical method and the cross section is given by monte - carlo simulation
用解析方法給出不變矩陣元，採用monte carlo模擬計算了強子物質中重子誘導。The experimental results show that : solution, nucleation and crystal growth are a continuous process. the induction effect is not apparent in the ethylene hydrate formation. the kinetic curves of ethylene in gaseous condition are very smooth with second nucleation happened in lower temperature and higher pressure
實驗結果表明：乙烯水合物生成的溶解、成核、生長的進行是一連續的過程，誘導過程不明顯甚至消失；常規條件下的乙烯動力學為一光滑連續的曲線，在較低溫度和較高壓力下會有二次成核現象；近臨界條件下乙烯生成水合物頻繁出現二次成核現象；超臨界條件下的乙烯由於其特殊的性質而使生成動力學行為變得更加復雜。The mutant pel - d92l was expressed in pichia pastoris gs115, sds - page detection showed that the expression product pel - d92l - gs is different from pel - gs, and its " yield decreased dramatically, the themostability of pel - d92l - gs is also different from the pel - gs, but their optimum temperatures are same. 3. directed evolution of pel through random mutagenesis mutagenesis pcr carried out in error - prone conditions was used on the vector psk - pel, using the oligos " beginning " and " end ", homologous to the 5 ' and to the 3 " ends of the gene of pel respectively
三、 pel基因的隨機誘變用易錯pcr方法對pel基因進行隨機誘變， pcr產物與ppic3 . 5k連接，轉化大腸桿菌，獲得的混合質粒電轉化畢赤酵母gs115 ， omm平板篩選適于低溫或對熱穩定的重組子，篩選獲得一株最活反應溫度、熱穩定性、發酵酶活均有提高的突變體pel - ep5 - gs ，其最活反應溫度為45 ，比野生型高出5 ； 40處理30min殘留活性為56 ，大大高於野生型的6 ；初始ph7 . 3528條件下培養72h ，發酵上清酶活為325u / ml 。Many researches were carried through in mammal animals showed that mitochondrial an er might have changed much after apoptosis induced by a variety of stimuli, including cytokines, anti - cancer drugs, growth factor deprivation and so on. however, few researches were gone on the apoptosis in the insect cells
在哺乳動物中的許多研究表明，各種誘導因素，如：抗癌藥物、除去生長因子和細胞因子等引起凋亡時，線粒體和內質網中都會經歷一系列的變化，而在昆蟲細胞中這個方面的研究比較少。分享友人