酶特異電極 的英文怎麼說
中文拼音 [tèyìdiànjí]
酶特異電極
英文
enzyme-specific elecrode- 酶 : 名詞[生物化學] （生物體的細胞產生的有機膠狀物質） enzyme; ferment
- 特 : Ⅰ形容詞（特殊; 超出一般） particular; special; exceptional; unusual Ⅱ副詞1 （特別） especially; v...
- 異 : 形容詞1 （有分別; 不相同） different 2 （奇異; 特別） strange; unusual; extraordinary 3 （另外的;...
- 電 : Ⅰ名詞1 （有電荷存在和電荷變化的現象） electricity 2 （電報） telegram; cable Ⅱ動詞1 （觸電） give...
- 極 : i 名詞1 （頂點; 盡頭） the utmost point; extreme 2 （地球的南北兩端; 磁體的兩端; 電源或電器上電流...
- 特異 : 1 （特別優異） exceptionally good; excellent; superfine2 （特殊） peculiar; distinctive特異功能 s...
- 電極 : electrode; pole
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A c a2 + / calmo dul in - dep endent pro te in kinas e i i ( c amkii ) antagoni st kn - 6 2 ( 5x l0 - ' mol / l ) presented in the intemal solution had no significan effect on the current peaks induced by extracellular nmda ( l0 # mol / l ), but prevented the inhibitory effect of b on inmda " these results indicate that gcs have rapid, reversible idebitory effects on lnmda intracellular application of b thiough microelectrode had no effect on inmda, howevet, extracellular application of b or b - bsa suppressed peaks of inmda : all these denote b exerts its influence on nmda receptor by cytoplasm membrane mechansms, which is naxnely rapid, nongenomic mechhasms
加有快速、可逆的。非濃度依賴性抑制作用。通過微電極將b直接導入細胞內， inmda不受影響，而胞外給予b或besa ， inmda減小，提示b對nmda受體的調控通過膜機制產生，這種作用與經典的基因組機制不同；因為廣譜激酶抑制劑和特異的pka抑制劑均可翻轉b的抑制效應， camk11抑制劑也可阻斷b的效應，而這些激酶抑制劑本身對inmda即有強烈的抑制作用： pka激動劑本身對inmda無明顯作用，也不影響b對l 。In order to get some functional clues from their structures, the upstream regulation region of ndrgl gene and second structure of ndrg2 protein are performed bioinformatics analysis ; we found that there are several binding sequences of some diffirent transcription factors, their functions include regulating tissue - specific gene expression, regulating expression of genes related to growth and early development of cells, besides this, regulating expression of genes under some stimulated conditions, and so on. predict in protein fold classification shows that ndrg2 belongs to alpha / beta hydrolase fold family, and there are high similarity between ndrg2 and epoxide hydrolase from bacteria, this suggests that ndrg2 protein may has enzymatic functions associated with resisting the oxidative stress, maintaining the balance of cell redox potential, involving in the metabolism process of xenobiotics or intracellular toxic molecules
研究發現呷基因的調控區存在多種轉錄因子結合位點，功能主要涉及組織特異性表達調控，細胞生長發育相關基因的表達調控，刺激反應基因的表達調控等； ndrgz蛋白在結構上屬于a小水解酶類折疊，折疊分類預測表明ndrg2與其中的的細菌環氧化物水解酶的二級結構極為相似，提示ndrgz蛋白具有一定酶活性，可能參與細胞抗氧化應激反應，維持細， an ） armtbffiofbfochmilsyn ） mdafblechmrbfobo4第四軍醫大學碩士學位論文胞內氧還電勢平衡，參與內外源有毒物質的代謝等。
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