b cell proliferation 中文意思是什麼

b cell proliferation 解釋
b細胞增殖
  • b :
  • cell : n 1 小室，單室；隔間，艙；〈詩〉茅舍；（單個的）蜂窩，蜂房。2 〈詩〉墓穴，墓。3 （大修道院附屬的...
  • proliferation : 繁茂
  1. The b lymphocyte stim lator ( blys ) also known as baff, tall - 1, thank, ztnf4, is the most recent addition to the tumor necrosis factor family ( tnf ) ligands. blys induces both in vivo and in vitro b cell proliferation, differentiation and immunoglob lin secretion. meanwhile, it also strongly suppresses the growth of tumor cell lines. the over - production of blys is associated with the development of certain autoimmune disease, such as systemic lupus erythaematosus ( sle ), rheumatoid arthritis, myasthenia gravis, sj greh ' s syndrome

    人b淋巴細胞刺激因子（ hblys ）是1999年發現的腫瘤壞死因子超家族成員。最早發現其可誘導腫瘤細胞凋亡，之後發現它是一個強有力的b細胞共刺激因子，它在體外及轉基因動物體內可明顯刺激b細胞的生長，免疫球蛋白分泌，並導致動物自身免疫性改變。
  2. Released by t helper cells, it facilitates t cell proliferation and differentiation, accelerates the growth of b cells, and activates monocyte and natural killer cells

    淋巴細胞分裂外，亦可促進b淋巴細胞的生長，活化單核球和自然殺手細胞
  3. The characteristics of this method are : a, directly counting cell number without the influence of the metabolic state of the cells ; b, discrimination of target cells from effector cells in cell - mediated cytotoxicity assay ; c, less treatment step, and free - radioactivity ; d, high sensitivity and reliability. 2, using the above assay, immunofluorescent labeled technique, and flow cytometry, the pbmc proliferation, apoptosis, necrosis, cell cycle, activation, cytokines and membrane marker were detected. the results showed that the number of pbmc reduced, but the activity of pbmc increased dose - dependently ; the reduction of cell number resulted from necrosis and apoptosis ; the supernatant of k562 cell lines were not able to block the cell cycle, but to promote it ; the ratio of t cell subset and the expression of thl and th2 cytokines increased

    結合以上創建的方法和免疫熒光流式細胞術，用k562細胞株可溶性分泌物（上清）對外周血單個核細胞（ pbmc ）進行培養以模擬體內微環境，然後分別從細胞增殖、凋亡、壞死、細胞周期、活性、細胞因子和表面抗原表達等方面進行研究，結果發現用腫瘤上清培養的pbmc細胞數量下降明顯，但同時對其有激活作用，且呈劑量依賴性；細胞數的下降主要是由細胞壞死和凋亡引起的，腫瘤上清對細胞周期沒有阻斷作用，反而略有促進作用； t細胞亞群比例增加，並促進表達th1 、 th2細胞因子。
  4. The recombinant was identified by dual enzyme digestion and the direction of cd40 / pcdna3 was analysed with t7 primer. after being packed by lipofectaminetm2000, the recombinant was transfected into b lymphocytes. cd40 expression on membrane, cell proliferation and antibodies concentration were detected with flowcytometry, mtt colorimety assay and el1sa, respectively

    以脂質體為介質瞬時轉染健康人及sle患者b細胞系，利用流式細胞技術檢測膜cd40的表達情況，並利用mtt比色法檢測細胞的增殖能力， elisa法檢測培養液的ig濃度，以研究b細胞在cd40被抑制以後增殖能力、抗體分泌的改變。
  5. The supernatant containing hsblys co - stimulated b cell proliferation highly with anti - igm by mtt analysis. flow cytometry results showed only in the function of costim lation, can b cell entered the s phase of cell cycle

    Mtt法知hsblys表達上清對b淋巴細胞具有共刺激作用；流式細胞儀分析顯示只有在共刺激作用下， b細胞才進入s期。
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