chimera mouse 中文意思是什麼
chimera mouse
解釋
嵌合體鼠-
Mass spectrometry of synthetic hw - ma and rgd - hw are in full agreement with those speculated theoretically, which proves the success of peptide synthesis and refold. on isolated mouse phrenic nerve - diaphragm preparations, hw - ma can block the neuromuscular transmission in 35 minutes or so ( l 10 - 5 g / ml ), its biological activity shows 73 % decrease comparing with biological activity of native hwtx - i. it proves t hat the protein engineering of synthetic chimera hwtx - i has gained success to some extent, although it did not achieve our expectations. thus it proved that hwtx - i can be using as natural scaffold for protein engineering. and also emphasized the importance of " local stereo circumstances " of activity site when the foreign activity site was transferred into a natural scaffold
濃度為1 / 1059 / ml的hw一ma突變體能可逆阻斷小白鼠隔神經書高肌的接頭傳遞，阻斷時一間為35min左右，與天然hwtx一i比較，生物學活性下降3一4倍，說明合成的突變體改造獲得了一定的成功，盡管與我們預期的目標有一定的差距，從而證明hwtx一i可以作為蛋白質工程研究的天然分子骨架，同時也強調了往天然分子骨架中轉移外源活性位點時維持活性位點「局部立體環境」的重要性。 -
This study did microinjection to kunming white mouse inbred embryos to test its in vitro developmental ability, then pluripotency of porcine eg cells was tested with production of chimera by blastocyst injection. finally, first chimeric pig in china was delivered, and by chimera analysis, chimerism is present in some tissues
本研究首先利用近交系昆明白小鼠進行胚胎顯微注射觀察發育效果，然後利用所獲五指山豬eg細胞製作嵌合體檢驗eg細胞多能性，最終獲得國內首例胚胎幹細胞（ eg細胞）嵌合體豬，經dna分析確認在多種組織中存在嵌合狀態。
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