transmembrane signaling 中文意思是什麼

transmembrane signaling 解釋
跨膜信號傳遞
  1. The two single - pass transmembrane proteins, delta and serrate, have been identified as notch ligands. the transcription factor suppressor of hairless [ su ( h ) ] is the major downstream effector of notch signaling pathway. rbp - j, the mammalian homolog of su ( h ), recognizes the core sequence ( c / tgtgggaa ) of dna

    Rbp - j是果蠅促神經發生基因su ( h ) ( suppressorofhairless )在哺乳動物的同源物,它通過其識別序列( c tgtgggaa )結合於受調控基因的啟動子區,在轉錄激活因子的驅動下調節細胞分化和個體發育相關基因的表達。
  2. Our previous work verified that heterotrimeric g protein was involved in regulation of pollen germination, tube growth and in the transmembrane mechanism of extracellular cam signal. in the present study, we provide further evidence that plc signaling pathway was presented in lily pollen and involved in extracellular cam signal transduction mechanism in pollen by molecular, biochemical and physiological approaches. these evidence included : the pip _ ( 2 ) - dependent plc activity was also detected in purified lily pollen protoplasts

    為了給上述信號轉導過程提供進一步的證據,本文以百合花粉為材料,從plc活性的測定、 plc基因的克隆及其與花粉萌發的關系、以及plc活性被g蛋白和cam調控等方面,為肌醇磷脂系統參與花粉萌發和細胞外鈣調素的信號轉導過程進一步提供了分子生物學和生物化學的證據。
  3. Catenin binds to the cytoplasmic tail of a transmembrane cell adhesion molecule - epithelial cadherin ( e - cadherin ) in epithelial cells and forms an adhesion complex [ e - cadherin - p - catenin ( or y - catenin ) - cc - catenin ] ( cadherin - catenin - complex, ccc ), this complex play an important role in maintaining epithelial cell adhesion. some catenins such as -, - and p120ctn catenins are also crucial in cell signaling, they play an important role in cell proliferation and cell apoptosis

    在上皮細胞內,連環蛋白均能與跨膜細胞粘附分子?上皮鈣粘蛋白( e - cadherin )的胞內肽段結合而形成了由上皮鈣粘蛋白- -連環蛋白( -連環蛋白) - -連環蛋白組成的粘附連接體( adherensjunctions , ajs ) ,這種復合體對維持細胞正常的粘附功能是必需的。
  4. There are still many questions remain unanswered, including the mechanisms that specify oligochitosan recognition, the participation of additional molecules in transmembrane signaling, and the repertoire of downstream pathways activated by oligochitosan. it was also observed that pdtc did not totally block no production, which gave us another evidence that there must be some other signal transduction pathways ( perhaps mapk, pkc, ca2 + dependent signaling ) involved in the activation, so further investigation is necessary to clarify molecular mechanism of oligochitosan inducing immunological en

    Westemblot結果顯示100林歲ml劑量的殼寡糖作用於raw264 . 7細胞( 4x105個細胞/ ml ) 4h ,胞核內p65的含量明顯增加, 6h時達到高峰, 10h時恢復到基礎表達量,這就提示在殼寡糖對巨噬細胞的激活過程中nf一kb活化狀態可以持續6個小時。
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