細胞激活抗原 的英文怎麼說

中文拼音 [xìbāojīhuókàngyuán]
細胞激活抗原 英文
t-cell activation antigen
  • 細 : 形容詞1 （條狀物橫剖面小） thin; slender 2 （顆粒小） in small particles; fine 3 （音量小） thin ...
  • 胞 : Ⅰ名詞1 （胞衣） afterbirth2 （同一個國家或民族的人） fellow countryman; compatriot Ⅱ形容詞（同胞...
  • 激 : Ⅰ動詞1 （水因受到阻礙或震蕩而向上涌） swash; surge; dash 2 （冷水突然刺激身體使得病） fall ill fr...
  • 活 : Ⅰ動詞1 （生存; 有生命） live 2 [書面語]（救活） save （the life of a person）:活人無算 （of a goo...
  • 抗 : Ⅰ動詞1 （抵抗; 抵擋） resist; combat; fight 2 （拒絕; 抗拒） refuse; defy 3 （對等） contend with...
  • 原 : Ⅰ形容詞1 （最初的; 原來的） primary; original; former 2 （沒有加工的） unprocessed; raw Ⅱ動詞（原...
  • 細胞 : cell; sytes; bioplast; cella; [口語] gene; [生物學] cellule; cellule cellulli cellulo ; cello ; k...
  • 激活 : activation; sensitization; activate; sensitize; active激活材料 active material; 激活劑 activating...
  1. Dendritic cells are characterized by their ability to efficiently present antigen, and are uniquely equipped to stimulate naive t cell responses. immature dendritic cells acquire antigens from throughout the peripheral body, then migrate to t - lymphocyte - dependent areas of lymph nodes. thus, dendritic cells act as bridges, operating at the interface of innate and acquired immunity

    作為機體免疫系統中功能最強的專職性抗原提呈細胞（ antigen - presentingcells ， apc ） ，樹突狀細胞（ dendriticcells ， dc ）能高效地攝取、加工處理和提呈抗原，具有較強的遷移能力，並能顯著地激活初始型t細胞以啟動t細胞免疫應答反應，此外， dc與b細胞以及nk細胞等也存在著相互作用，可見， dc在連接天然免疫和獲得性免疫之間起著非常重要的作用。
  2. Activation of the complement may lead to killing of the microorganisms by direct lysis effect of complement system or the phagocytosis by the enhancement of the attachment of microbes to the phagocyte ( opsonization ). low serun concentrations of mbl in man is the basis for a common opsonic defect associated with recurrent infection

    它可選擇性識別多種病原體表面的糖結構，以不依賴抗體和c1q的方式激活補體，發揮溶破和間接調理功能，還能與吞噬細胞膠凝素受體結合而起直接調理作用。
  3. The characteristics of this method are : a, directly counting cell number without the influence of the metabolic state of the cells ; b, discrimination of target cells from effector cells in cell - mediated cytotoxicity assay ; c, less treatment step, and free - radioactivity ; d, high sensitivity and reliability. 2, using the above assay, immunofluorescent labeled technique, and flow cytometry, the pbmc proliferation, apoptosis, necrosis, cell cycle, activation, cytokines and membrane marker were detected. the results showed that the number of pbmc reduced, but the activity of pbmc increased dose - dependently ; the reduction of cell number resulted from necrosis and apoptosis ; the supernatant of k562 cell lines were not able to block the cell cycle, but to promote it ; the ratio of t cell subset and the expression of thl and th2 cytokines increased

    結合以上創建的方法和免疫熒光流式細胞術，用k562細胞株可溶性分泌物（上清）對外周血單個核細胞（ pbmc ）進行培養以模擬體內微環境，然後分別從細胞增殖、凋亡、壞死、細胞周期、活性、細胞因子和表面抗原表達等方面進行研究，結果發現用腫瘤上清培養的pbmc細胞數量下降明顯，但同時對其有激活作用，且呈劑量依賴性；細胞數的下降主要是由細胞壞死和凋亡引起的，腫瘤上清對細胞周期沒有阻斷作用，反而略有促進作用； t細胞亞群比例增加，並促進表達th1 、 th2細胞因子。
  4. Dendritic cells ( dc ) is the most powerful apc, which can markedly increase the antigen - presentation capacity by maximizing the pepitide - mhc complexes on the cell surface and upregulating the co - stimulatory ligands b7 - 1 and b7 - 2, adhesion moleculees such as il - 12 that promote full activation of lymphocytes. full activation of antigen - specific t cells requires two signals - one signal coming via the tcr and the other signal through engagment of co - stimulatary molecules. t cells receiving one signal via their tcr are turned off by mhc ( major histocompatibility complex ), via t cell cd28 binding to b7 on the dc induce tlymphokine and t cell proliferatiion

    T細胞介導的細胞免疫在控制腫瘤生長方面發揮著重要作用， t細胞在發揮抗瘤效應（分泌細胞因子和直接殺傷）之前必須先經過活化，體內專職抗原提呈細胞（ apc ）細胞並使其活化，樹突狀細胞（ dendriticcell ， dc ）為t細胞的激活提供雙重信號， t細胞藉助tcr識別由dcmhc分子遞交的抗原肽后，通過tcr - cd3復合體傳遞抗原特異性識別信號（第一信號） ，以cd28為主的t細胞表面輔佐分子識別dc表面b7分子，傳遞非特異性協同刺激信號（第二信號） ，在機體抗腫瘤免疫應答中處于核心地位。
  5. Dendritic cells ( dc ), the initiator and modulator of immune response, are the most powerful professional antigen - presenting cells ( apc ). recent studies indicated that dc have the most power to activate tumor specific ctl, therefore, dc are applied in the therapy of tumors, e

    機體的抗腫瘤免疫主要為t淋巴細胞所介導， t細胞的致敏、激活、擴增和對腫瘤細胞的殺傷作用均有賴于抗原遞呈細胞腫瘤遞呈相應的抗原肽及相關因子的參與。
  6. It contains dha known for increase the resistibility against stimulate and pollution of environment

    深海魚油能增強肌膚對外界刺激和污染的抵抗力，為肌膚提供膠原蛋白之餘，補充細胞的活力。
  7. Effective activation of antigen - specific t cells not only requires the first signal transduction through t - cell receptor ( tcr ) binding with peptide - mhc complex on the antigen presenting cell ( apc ), but also needs the second signal, termed costimulation. costimulation critical to the degree and consequence of t cell activation is provided by interaction between soluble factors or cell - surface molecules on the t cell and on the apc

    而t細胞的活化除需要t細胞受體（ tcr ）與抗原呈遞細胞（ antigenpresentingcell ， apc ）表面的抗原肽- mhc復合物結合所形成的第一信號外，還需要t細胞和apc表面的其它膜分子結合所提供的共刺激信號（亦稱第二信號或輔助刺激信號， costimulatorysignal ）的參與。
  8. To circumvent these deficits, novel antigen - delivery systems utilizing cytokine gene - modified tumor cells and dc or fusion of dc with tumor cells have resulted in induction of antitumor immunity. however, this u approach is difficult in some cases ( for example in breast cancer ) because only rarely has it been possible to isolate enough viable tumor cells from an individual to prepare the vaccine

    為了克服上述缺陷，有學者採用滅活的腫瘤細胞、腫瘤抗原提取物（包括腫瘤細胞裂解物、 it na和洗脫肽等）沖擊致敏dc或將腫瘤細胞與dc融合后再回輸體內以激發機體的抗腫瘤免疫應答，也取得了較好的療效。
  9. When an infectious pathogen ( a disease - causing agent ) enters the body, b cells are activated and release antibodies into the bloodstream to combat the pathogen

    當一個感染性病原體（致病源）進入體內， b細胞就能被激活並釋放抗體進入血液抵抗病原體。
  10. Activated dc cells promote the antigen to repress tumor metastasis, the breakdown product of cancer cellular necrosis also exciting immunologic system

    活化dc細胞促進抗原呈抑制腫瘤轉移，壞死癌細胞分解產物刺激增強免役系統
  11. Macrophage is a kind of immune cell as well as accessory cell. it can function as antiinfection, anticancer, immune response and immunoregulation by phagocytosis, antigen presentation, cytokines secretion, lymphocyte activation, reactive oxygen and no production. it ' s an important part of body immune system

    巨噬細胞（ macrophage ）既是免疫細胞，又是輔佐免疫應答細胞，可通過吞噬、抗原呈遞、分泌細胞因子、激活淋巴細胞和產生活性氧、 no等作用而行使抗感染、抗腫瘤、免疫應答和免疫調節作用，是機體免疫系統的重要組成部分。
  12. Rapl belongs to ras superfamily of small gtp - binding proteins, which is considered to control cell growth, differentiation and survival. rapl was regarded as an antagonist of ras because it can revert the phenotype of oncogene ras transformed cells. recent researches show that rapl has its ras - independent functions in a variety of cellular systems besides its effect as an antagonist of ras

    Rap1除具有逆轉原癌基因ras激活突變體所導致的細胞形態改變而被認為是ras的拮抗物外，最近的研究還發現rap1在一系列的細胞系統中有獨立於ras之外的功能，如控制與細胞粘附有關的事件等，因而成為研究的熱點。
  13. Changes of hemofat in activation of red blood cell innate immune reaction main road by antigen

    抗原激活紅細胞天然免疫反應主幹道血脂含量變化實驗研究
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