腫瘤特異抗原 的英文怎麼說
中文拼音 [zhǒngliútèyìkàngyuán]
腫瘤特異抗原
英文
tsa- 腫 : Ⅰ名詞(隆起處) swelling Ⅱ動詞(突起) swell; be swollen
- 瘤 : 名詞(瘤子) tumour
- 特 : Ⅰ形容詞(特殊; 超出一般) particular; special; exceptional; unusual Ⅱ副詞1 (特別) especially; v...
- 異 : 形容詞1 (有分別; 不相同) different 2 (奇異; 特別) strange; unusual; extraordinary 3 (另外的;...
- 抗 : Ⅰ動詞1 (抵抗; 抵擋) resist; combat; fight 2 (拒絕; 抗拒) refuse; defy 3 (對等) contend with...
- 原 : Ⅰ形容詞1 (最初的; 原來的) primary; original; former 2 (沒有加工的) unprocessed; raw Ⅱ動詞(原...
- 腫瘤 : tumour; core (綿羊體內的); neoplasm; phyma
- 特異 : 1 (特別優異) exceptionally good; excellent; superfine2 (特殊) peculiar; distinctive特異功能 s...
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These findings of the specific ctls epitopes in irbp and pedf may lead to improved understanding of the pathogenesis of uveitis. our study also provides a strategy to identify specific ctls epitopes within tumour antigen, which is helpful to make tumour vaccine for the patients
本研究也為尋找腫瘤抗原中具有誘導特異性ctls能力的肽片段提供了一種策略,為制備肽片段腫瘤疫苗提供了理論基礎。Dendritic cells ( dc ) is the most powerful apc, which can markedly increase the antigen - presentation capacity by maximizing the pepitide - mhc complexes on the cell surface and upregulating the co - stimulatory ligands b7 - 1 and b7 - 2, adhesion moleculees such as il - 12 that promote full activation of lymphocytes. full activation of antigen - specific t cells requires two signals - one signal coming via the tcr and the other signal through engagment of co - stimulatary molecules. t cells receiving one signal via their tcr are turned off by mhc ( major histocompatibility complex ), via t cell cd28 binding to b7 on the dc induce tlymphokine and t cell proliferatiion
T細胞介導的細胞免疫在控制腫瘤生長方面發揮著重要作用, t細胞在發揮抗瘤效應(分泌細胞因子和直接殺傷)之前必須先經過活化,體內專職抗原提呈細胞( apc )細胞並使其活化,樹突狀細胞( dendriticcell , dc )為t細胞的激活提供雙重信號, t細胞藉助tcr識別由dcmhc分子遞交的抗原肽后,通過tcr - cd3復合體傳遞抗原特異性識別信號(第一信號) ,以cd28為主的t細胞表面輔佐分子識別dc表面b7分子,傳遞非特異性協同刺激信號(第二信號) ,在機體抗腫瘤免疫應答中處于核心地位。Focus on research work and clinical studies in musculoskeletal oncology, especially about mechanism and biological therapy of osteosarcoma, such as proteomics studies of osteosarcoma, prospective control study of osteosarcoma, registration system of musculoskeletal oncology and genic tests about the familial inheritance osteoenchondroma, etc
擬開展《骨肉瘤特異性相關抗原的蛋白質組學研究》 、 《骨肉瘤多中心前瞻性隨機對照研究》 、 《骨與軟組織腫瘤注冊-會診-隨訪登記系統》 、 《多發性骨軟骨瘤家族遺傳性基因的檢測》等課題的相關研究工作,承擔國家、省級和市級重大項目等課題的申報。Tumor antigens of hepatocellular carcinoma and its specific cellular immunity
肝癌的腫瘤抗原與特異性細胞免疫It delivers the false ? folding peptides for presentation to proteasomes in normal cells, while in tumor cells it acts as main tumor - resistant antigen, inducing specific immune response. recent research found that grp94 also relates with cell cycles, differentiation and apoptosis
此外發現它還具有抗原提呈作用,在正常細胞中參與折疊錯誤蛋白到蛋白酶體的提呈;在腫瘤細胞中作為主要的腫瘤排斥抗原,引發針對該腫瘤細胞的特異性免疫反應。Objective : in most t eel ] malignancies, there are t cell receptors ( tcr ) expressed on the surface of the tumor cells
目的:大多數t細胞腫瘤表面有tcr獨特型抗原,可作為腫瘤特異性抗原用於免疫治療。Ascribed to the discoveries of many tumor specific / associated antigens ( tsas / taas ) and the unique / excellent properties of antibody, the antibody - mediated targeting therapy of tumor persistently attracts worldwide attentions
由於許多腫瘤特異性抗原或相關抗原被發現以及抗體具有獨特而優越的性能,抗體介導的腫瘤靶向治療一直受到廣泛關注。Filamentous bacteriophage displayed tumor - specific antigen epitope mage - a1 induced cellular immune in mice
展示腫瘤特異性抗原表位的噬菌體在小鼠體內引起的細胞免疫變化On the other hand, the expression is repressed by the proto - oncogenes n - myc and c - myc, and in some cases the expression is also repressed by testosterone or dihydrotestosterone ( androgen ) at mrna level infering from all the references that can be obtained, the functions of ndrg family may be involved in cellular differentiation events > maintaining the balance of cell redox potential ( in oxidative stress condition or biological conversion process ), or counteracting cell malignant transformation, and so on
綜合己有的文獻,推測ndrg家族可能參與細胞生長分化、維持細胞氧化還原電勢平衡(氧化應激或生物轉化) 、阻止腫瘤細胞惡化等。因此,研究其在細胞中的具體功能以及可能的信號通路將具有非常重要的意義。深人研究ndrgz在體內的組織細胞和亞細胞水平分佈特點及其功能,需要高效價和高特異性的ndrgz抗體。The ability to target psma on blood essels would proide a way to directly attack a tumor ' s blood supply without affecting normal blood essels
因此特異針對血管的psma抗原可以在腫瘤治療時直接阻斷腫瘤的血液供應,而不影響正常血管的功能。分享友人