還原酶類 的英文怎麼說
中文拼音 [háiyuánlèi]
還原酶類
英文
phmg coa reductases- 還 : 還副詞1 (表示現象繼續存在或動作繼續進行; 仍舊) still; yet 2 (表示在某種程度之上有所增加) even...
- 原 : Ⅰ形容詞1 (最初的; 原來的) primary; original; former 2 (沒有加工的) unprocessed; raw Ⅱ動詞(原...
- 酶 : 名詞[生物化學] (生物體的細胞產生的有機膠狀物質) enzyme; ferment
- 類 : Ⅰ名1 (許多相似或相同的事物的綜合; 種類) class; category; kind; type 2 (姓氏) a surname Ⅱ動詞...
- 還原 : 1 (恢復原狀) return to the original condition or shape; restore2 [化學] (還原作用) reduction;...
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Three - dimensional quantitative structure activity relationship of flavones as aldose reductase inhibitors
黃酮類醛糖還原酶抑制劑的三維定量構效關系研究Thioredoxins, an ubiquitous small proteins with a redox active disulfide bridge in its conserved motif - cp ( g ) pc -, are universally distributed in eucaryote and procaryote and have a molecular mass of approximately 12kda. by its disulfide / dithiol interchange reaction, this protein can transmit the regulatory signals to seleted targets ( enzymes, transcription factors etc ) and plays an important role in many plant physiological processes that includes photosynthesis, dna synthesis, transcription, protein disulfide reduction, protein repair, filamentous phage assembly, cell apoptosis and seeds germinating and so on
該蛋白質中含有保守的- cp ( g ) pc -氨基酸活性基序,該基序中的兩個半胱氨酸殘基可通過巰基二硫鍵的轉換實現其氧化還原狀態的變化和電子氫的傳遞,對細胞中與氧化還原相關的多種生理過程的調節起重要作用。通過同許多酶類、蛋白類、細胞內活性因子相藕連, trx能對光合作用、 dna復制、基因轉錄、細胞凋亡和生長、噬菌體組裝、蛋白質的還原和修復信號傳導等生理過程產生影響和調節。They discovered that existing anti - fungal treatments based on azoles already target p450s, for instance in the treatment for candida albicans ( the causative agent of thrush )
他們還發現現有的存在於抗真菌治療藥物中的氮雜茂已經具有針對p450酶類的靶點,比如用於白色念珠菌(鵝口瘡的病原體)治療時。The sequences of intron, however, had only 74 % of homology with those of a. thaliana ban. in addition, amino acid sequence of oilseed rape ban had 78 % of homology and 87 % of similarity with those of a. thaliana and had various homologies ( 55 - 64 % ) with many nadph - dependent reductases of other plants
將甘藍型油菜ban氨基酸序列進行同源比較,發現甘藍型油菜ban片段的181個氨基酸與擬南芥有78的氨基酸序列相同,相似性達87 ;與80多種植物的nadph還原酶類也有不同程度的同源性( 55 - 64 ) 。This approach includes lifestyle modifications, such as dietary changes and smoking cessation and the use of hmg - coa reductase inhibitors ( statins ), which are able to correct the lipid status and to prevent major cardiovascular events independently of the baseline lipidaemic or cardiovascular status
這些方法包括生活方式的改變,如飲食改變,戒煙以及運用-羥- -甲基戊二酸單酰輔酶a還原酶抑制劑(他汀類藥物) ,從而糾正脂類情況和預防非依賴性膽固醇血癥的主要心血管事件或心血管狀態。The rat 20a - hydroxysteroid dehydrogenase ( 20ahsd ) belongs to a family member of aldo - ketoreductases used nadph as a cofactor and principally converts progesterone to 20a - hydroxyprogesterone as a lower or non - active hormone. thus 20ohsd acts as a molecular switch and makes the potent progesterone hormone into an inactive potent metabolite
大鼠20 -羥類固醇脫氫酶( 20 - hydroxysteroiddehydrogenase , 20 hsd )屬于醛酮氧化還原酶系成員,在大鼠卵巢中以nadph為輔酶將孕酮轉變為低或無活性的20 -羥孕酮。L l6 - hsd2 is localized to the sppytiotrophoblast of the placenty providing a fimctional barrier protecting the fetus from matemal glucocorticoids. a sequence resembling glucocorticoid response element ( gre ) has been identified in the promoter region of the human l l0 - hsdl gene. glucocorticoids have been shown to induce the expression of 11p - hsdl in the hippomus in vitro " whereas controversial results were obtained in the hepatocyte
體內至少存在兩型11 - hsd ,在細胞完整的狀態下, 11 - hsd1主要為還原酶,它活化gc的代謝產物17 -羥- 11 -脫氫皮質酮(嚙齒類為脫氫皮質酮)為有活性的皮質醇(嚙齒類為皮質酮) ,而11 - hsd2為氧化酶,它催化皮質醇為無活性的17 -羥- 11 -脫氫皮質酮,因此11 - hsd1加強gc的作用,而11 - hsd2減弱gc的作用。Nitric oxide can be produced in plant cells via animal no synthase ( nos ) or nitrate reductases and through nonenzymatic reactions
摘要植物體可以通過依賴于類似哺乳動物的一氧化氮合成酶或硝酸還原酶的酶促合成途徑和非酶促合成途徑產生一氧化氮。More intriguingly, in hippocampus, 11 - hsd1 and gr were found to co - exist in the same neuron ; and 11 - hsd1 can convert biologically inert 11 - keto gc metabolites into biologically active gc. gc regeneration by 11 - hsd1 will concentrate gc locally to enable its interaction with the low - affinity gr
而11 - hsd1具有氧化還原酶的雙重催化作用,廣泛存在於糖皮質激素的靶器官,如肝臟、神經系統、胎盤和胎膜,其催化方向取決于組織類型和功能狀態。分享友人