endocrine obesity 中文意思是什麼
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Based on the results of the pilot programme, the cuhk diabetes and endocrine centre, under the auspices of the hong kong foundation for research and development in diabetes, and the cuhk centre for nutritional studies of the school of public health will jointly launch a self - funded 6 - month obesity management programme combining pharmacological therapy and behaviour modification to facilitate high risk obese subjects to achieve realistic weight reduction and improvement of their risk profiles
香港中文大學糖尿及內分泌中心獲香港糖尿病研究發展基金會的資助，將與中大公共衛生學院轄下的營養研究中心合辦六個月自費的體重管理計劃（ obesitymanagementprogramme ） ，根據上述研究的結果，利用藥物治療及跟進行為的方法，幫助高危的肥胖人士減輕體重及改善其健康情況。 -
Because osteocalcin is produced only by osteoblasts yet acts on cells far away in the pancreas, the researchers concluded that bone is part of the endocrine system, and that it may hold a key to both obesity and diabetes
因為骨鈣素僅由造骨細胞產生但是卻對遠在胰腺的細胞起作用，研究人員得出得出結論：骨骼是內分泌系統的一部分，而且是肥胖和糖尿病的關鍵。 -
Adipokines, the bioactive factors derived mainly from adipocytes, regulate pancreatic - cell function including insulin secretion, gene expression and apoptosis. in this review, we propose that adipokines influence - cell function through three interdependent pathways. the first is through regulating lipid and glucose metabolism in - cells. the second implicates the change of ion channel opening and closing in - cells. the third pathway is via the modification of insulin sensitivity of - cells. the endocrine function of adipocytes is dynamic, and the secretion of various adipokines changes under different metabolic conditions. during the progression from the normal state to obesity and to type 2 diabetes, adipokines contribute to the occurrence and development of - cell dysfunction in type 2 diabetes
脂肪因子包括脂肪細胞分泌的多種活性因子，它們通過內分泌方式調節胰島細胞的胰島素分泌、基因表達以及細胞凋亡等多方面的功能.本文提出脂肪因子影響胰島細胞功能主要通過三條相互聯系的途徑而實現.第一是調節細胞內葡萄糖和脂肪的代謝;第二是影響細胞離子通道的活性;第三是改變細胞本身的胰島素敏感性.脂肪細胞的內分泌功能是一個動態過程，在不同的代謝狀態下，各脂肪因子的分泌發生不同變化.從正常代謝狀態發展到肥胖以及2型糖尿病的過程中，脂肪因子參與了胰島細胞功能障礙的發生與發展 -
Abstract : adipokines, the bioactive factors derived mainly from adipocytes, regulate pancreatic - cell function including insulin secretion, gene expression and apoptosis. in this review, we propose that adipokines influence - cell function through three interdependent pathways. the first is through regulating lipid and glucose metabolism in - cells. the second implicates the change of ion channel opening and closing in - cells. the third pathway is via the modification of insulin sensitivity of - cells. the endocrine function of adipocytes is dynamic, and the secretion of various adipokines changes under different metabolic conditions. during the progression from the normal state to obesity and to type 2 diabetes, adipokines contribute to the occurrence and development of - cell dysfunction in type 2 diabetes
文摘:脂肪因子包括脂肪細胞分泌的多種活性因子，它們通過內分泌方式調節胰島細胞的胰島素分泌、基因表達以及細胞凋亡等多方面的功能.本文提出脂肪因子影響胰島細胞功能主要通過三條相互聯系的途徑而實現.第一是調節細胞內葡萄糖和脂肪的代謝;第二是影響細胞離子通道的活性;第三是改變細胞本身的胰島素敏感性.脂肪細胞的內分泌功能是一個動態過程，在不同的代謝狀態下，各脂肪因子的分泌發生不同變化.從正常代謝狀態發展到肥胖以及2型糖尿病的過程中，脂肪因子參與了胰島細胞功能障礙的發生與發展
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